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List of works by Twan van den Beucken

A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases

scientific article published on 9 February 2018

Author Correction: Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression

scientific article published on 03 June 2020

Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity

scientific article

Control of the hypoxic response through regulation of mRNA translation.

scientific article

Deficient carbonic anhydrase 9 expression in UPR-impaired cells is associated with reduced survival in an acidic microenvironment

scientific article

Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

scientific article published on 12 June 2011

Dynamic Interplay between the Transcriptome and Methylome in Response to Oxidative and Alkylating Stress.

scientific article published on 10 August 2016

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

scientific article

Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T

scientific article published on 29 June 2011

Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3.

scientific article published on 26 October 2016

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

scientific article

Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response

scientific article published on 29 June 2009

Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression

scientific article

Identification of essential transcription factors for adequate DNA damage response after benzo(a)pyrene and aflatoxin B1 exposure by combining transcriptomics with functional genomics

scientific article

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.

scientific article published on 7 March 2013

Persistent transcriptional responses show the involvement of feed-forward control in a repeated dose toxicity study

scientific article published on 17 October 2016

Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia.

scientific article published on 24 May 2007

Phosphorylation of eIF2α promotes cell survival in response to benzo[a]pyrene exposure

scientific article published on 29 October 2018

Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress

article

Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia

scientific article (publication date: November 2016)

Regulation of Cited2 expression provides a functional link between translational and transcriptional responses during hypoxia

scientific article published on 17 May 2007

Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies

scientific article published on April 2009

Targeting hypoxia tolerance in cancer

scientific article published on February 2004

The hypoxic proteome is influenced by gene-specific changes in mRNA translation

scientific article published on August 2005

The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency

scientific article published in March 2008

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

scientific article

Translational control is a major contributor to hypoxia induced gene expression

scientific article published on 28 June 2011

Translational control of gene expression during hypoxia

scientific article published on July 2006

Translational regulation is a key determinant of the cellular response to benzo[a]pyrene

scientific article published on 12 June 2018

Valproic acid promotes mitochondrial dysfunction in primary human hepatocytes in vitro; impact of C/EBPα-controlled gene expression

scientific article published on 04 July 2020

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