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List of works by Atsushi Hirao

A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells

scientific article published on 21 October 2005

Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence

scientific article published on March 18, 2013

Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.

scientific article published on 11 July 2003

Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas.

scientific article published on 26 July 2018

Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response

scientific article

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

scientific article

Combination therapy using Notch and Akt inhibitors is effective for suppressing invasion but not proliferation in glioma cells

scientific article published on December 20, 2012

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.

scholarly article

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

scientific article published on 30 January 2002

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

scientific article published in June 2007

Hematopoietic stem cell niche in bone marrow

scientific article

Hematopoietic stem cells and their niche.

scientific article

Identification of 2-fluoropalmitic acid as a potential therapeutic agent against glioblastoma

scientific article published on 28 April 2020

Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug

scientific article published on 4 December 2017

Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity

scientific article published on 18 September 2008

Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.

scientific article published on 17 September 2009

Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells

scientific article

JLP-JNK signaling protects cancer cells from reactive oxygen species-induced cell death.

scientific article

Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells

scientific article published on 24 February 2014

Maintenance of genomic integrity in hematopoietic stem cells

scientific article published on 09 March 2011

Mechanistic / mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia

scientific article published on 09 June 2013

Molecular pathology of tumor‐initiating cells: Lessons from Philadelphia chromosome‐positive leukemia

scientific article published on June 22, 2011

NKX2.2 suppresses self-renewal of glioma-initiating cells.

scientific article published on 17 December 2010

Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death

scientific article published on 2 October 2007

Novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells

scientific article published on 05 April 2010

Nucleostemin in injury-induced liver regeneration

scientific article published on 9 July 2012

Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis

scientific article published on 23 June 2014

Premeiotic germ cell defect in seminiferous tubules of Atm-null testis.

scientific article published on 3 November 2006

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

scientific article published on 26 March 2006

Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function

scientific article published on 25 January 2019

Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules

scientific article published on 13 February 2017

Regulation of cell cycle in hematopoietic stem cells by the niche

scientific article

Regulation of hematopoiesis and its interaction with stem cell niches.

scientific article

Regulation of hematopoietic stem cells by the niche.

scientific article

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

scientific article

Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells

scientific article published in November 2008

Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes

scientific article published in January 2007

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

scientific article

Regulation of the self-renewal ability of tissue stem cells by tumor-related genes

scientific article published on January 2007

Regulation of the self-renewal ability of tissue stem cells by tumor-related genes

article

Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest

scientific article

Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells

scientific article published on 8 October 2014

TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

scientific article

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

scientific journal article

Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells

scientific article published on 8 August 2011

[Regulation of self-renewal of hematopoietic stem cells in the niche].

scientific article published in June 2005