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List of works by Leah E Mechanic

A Review of NCI's Extramural Grant Portfolio: Identifying Opportunities for Future Research in Genes and Environment in Cancer ⬇️

scientific article published on March 5, 2013

Approaches to integrating germline and tumor genomic data in cancer research

scientific article

Association of MTHFR gene polymorphisms with breast cancer survival

scientific article published on 27 October 2006

Association of matrix metalloproteinase-1 polymorphisms with risk of COPD and lung cancer and survival in lung cancer ⬇️

scientific article published on September 1, 2012

Associations between anthropometry, cigarette smoking, alcohol consumption, and non-Hodgkin lymphoma in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

scientific article

Childhood exposure to secondhand smoke and functional mannose binding lectin polymorphisms are associated with increased lung cancer risk

scientific article

Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors

scientific article published in February 2007

Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases

scientific article

Differential Serum Cytokine Levels and Risk of Lung Cancer Between African and European Americans

scientific article published on 28 December 2015

EGFR Somatic Mutations in Lung Tumors: Radon Exposure and Passive Smoking in Former- and Never-Smoking U.S. Women ⬇️

scientific article published on April 20, 2012

Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study

scientific article

Exploring SNP-SNP interactions and colon cancer risk using polymorphism interaction analysis

scientific article

Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report

scientific article

Genetic Simulation Resources: a website for the registration and discovery of genetic data simulators ⬇️

scientific article published on February 23, 2013

Genetic data simulators and their applications: an overview

scientific article (publication date: 2015)

Genetic simulation tools for post-genome wide association studies of complex diseases

scientific article

Increased Levels of Circulating Interleukin 6, Interleukin 8, C-Reactive Protein, and Risk of Lung Cancer ⬇️

scientific article published on June 17, 2011

International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways

scientific article

Known glioma risk loci are associated with glioma with a family history of brain tumours--a case-control gene association study

journal article published in 2013

Lessons Learned From Past Gene-Environment Interaction Successes

scientific article published in October 2017

Leveraging biospecimen resources for discovery or validation of markers for early cancer detection

scientific article

Lung cancer survival and functional polymorphisms in MBL2, an innate-immunity gene.

scientific article

Manganese superoxide dismutase gene coding region polymorphisms lack clinical incidence in general population

scientific article published on June 2008

Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer

scientific article

NCI think tank concerning the identifiability of biospecimens and “omic” data ⬇️

scientific article published on April 11, 2013

Next generation analytic tools for large scale genetic epidemiology studies of complex diseases

scientific article

Nitric oxide is a key component in inflammation-accelerated tumorigenesis

scientific article

Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies

scientific article published on 14 July 2017

Pharmacogenomics in oncology care

scientific article published on 08 April 2014

Planned variation in preanalytical conditions to evaluate biospecimen stability in the National Children's Study (NCS).

scientific article

Polymorphism Interaction Analysis (PIA): a method for investigating complex gene-gene interactions

scientific article

Polymorphisms in XPD and TP53 and mutation in human lung cancer

scientific article

Quantitative detection of p53 mutations in plasma DNA from tobacco smokers

scientific article published on August 2006

Review of the Gene-Environment Interaction Literature in Cancer: What Do We Know?

scientific article

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

scientific article published on 29 July 2015

SERPINA1 and ELA2 polymorphisms are not associated with COPD or lung cancer ⬇️

scientific article published on September 1, 2012

Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians

scientific article published on January 2009

Serum estrogen and tumor-positive estrogen receptor-alpha are strong prognostic classifiers of non-small-cell lung cancer survival in both men and women ⬇️

scientific article published on August 20, 2010

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

scientific article

The mannose-binding lectin (MBL2) haplotype and breast cancer: an association study in African-American and Caucasian women

scientific article published on 27 October 2006

The use of biospecimens in population-based research: a review of the National Cancer Institute's Division of Cancer Control and Population Sciences grant portfolio

scientific article

Traceback: A Proposed Framework to Increase Identification and Genetic Counseling of BRCA1 and BRCA2 Mutation Carriers Through Family-Based Outreach

scientific article published on 11 April 2017

Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology

scientific article published on 28 September 2017

p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis.

scientific article published on April 2004

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