Search filters

List of works by Joachim Morschhäuser

A Global Analysis of Kinase Function in Candida albicans Hyphal Morphogenesis Reveals a Role for the Endocytosis Regulator Akl1.

scientific article published on 8 February 2018

A Hyperactive Form of the Zinc Cluster Transcription Factor Stb5 Causes YOR1 Overexpression and Beauvericin Resistance in Candida albicans.

scientific article published on 26 November 2018

A Suppressor Mutation in the β-Subunit Kis1 Restores Functionality of the SNF1 Complex in <i>Candida albicans snf4</i>Δ Mutants

scientific article published on 15 December 2021

A Zinc Cluster Transcription Factor Contributes to the Intrinsic Fluconazole Resistance of Candida auris

scientific article published on 22 April 2020

A family of oligopeptide transporters is required for growth of Candida albicans on proteins

scientific article published in May 2006

A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.

scientific article published on 16 May 2008

A human-curated annotation of the Candida albicans genome

scientific article

A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

scientific article

A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases

article by Harald Kusch et al published April 2008 in International Journal of Medical Microbiology

A role for antibodies in the generation of memory antifungal immunity

scientific article published in May 2003

A transcription factor regulatory cascade controls secreted aspartic protease expression in Candida albicans

scientific article published on 28 June 2008

Activation of the Cph1-dependent MAP kinase signaling pathway induces white-opaque switching in Candida albicans

scientific article

Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in Candida albicans

scientific article published on 28 April 2020

An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans

scientific article

An Intragenic Recombination Event Generates a Snf4-Independent Form of the Essential Protein Kinase Snf1 in Candida albicans.

scientific article published on 19 June 2019

An acquired mechanism of antifungal drug resistance simultaneously enables Candida albicans to escape from intrinsic host defenses.

scientific article published on 27 September 2017

Analysis of a fungus‐specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation ⬇️

scientific article published on July 25, 2013

Baculiferins A-O, O-sulfated pyrrole alkaloids with anti-HIV-1 activity, from the Chinese marine sponge Iotrochota baculifera

scientific article published on 23 June 2010

CARE-2 fingerprinting of Candida albicans isolates

scientific article published in January 2005

Calcineurin is essential for virulence in Candida albicans

scientific article published on September 2003

Candida albicans MTLalpha tup1Delta mutants can reversibly switch to mating-competent, filamentous growth forms

scientific article

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers.

scientific article

Candida parapsilosis Mdr1B and Cdr1B Are Drivers of Mrr1-Mediated Clinical Fluconazole Resistance

scientific article published in 2022

Cerulenin analogues as inhibitors of efflux pumps in drug-resistant Candida albicans

scientific article published in March 2009

Characterization of biofilm formation and the role of BCR1 in clinical isolates of Candida parapsilosis

scientific article

Chlamydospore formation in Candida albicans and Candida dubliniensis--an enigmatic developmental programme

scientific article

Cis-Configured aziridines are new pseudo-irreversible dual-mode inhibitors of Candida albicans secreted aspartic protease 2.

scientific article published in February 2008

Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains

scientific article published on May 2017

Contribution of Clinically Derived Mutations in the Gene Encoding the Zinc Cluster Transcription Factor Mrr2 to Fluconazole Antifungal Resistance and CDR1 Expression in Candida albicans

scientific article published on 25 April 2019

Control of ammonium permease expression and filamentous growth by the GATA transcription factors GLN3 and GAT1 in Candida albicans

scientific article published on 16 March 2007

Control of morphogenesis, protease secretion and gene expression in Candida albicans by the preferred nitrogen source ammonium

scientific article

Differential expression of the NRG1 repressor controls species-specific regulation of chlamydospore development in Candida albicans and Candida dubliniensis

scientific article

Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1.

scientific article

Disruption of homocitrate synthase genes in Candida albicans affects growth but not virulence

scientific article published on 23 June 2010

Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2

scientific article

Environmental induction of white-opaque switching in Candida albicans

scientific article

Evolution of Fluconazole-Resistant Candida albicans Strains by Drug-Induced Mating Competence and Parasexual Recombination

scientific article published in 2019

Expression of the CDR1 efflux pump in clinical Candida albicans isolates is controlled by a negative regulatory element.

scientific article

Factors supporting cysteine tolerance and sulfite production in Candida albicans

scientific article

Functional Dissection of a Candida albicans Zinc Cluster Transcription Factor, the Multidrug Resistance Regulator Mrr1 ⬇️

scientific article published on June 17, 2011

Functional analysis of CaRAP1 , encoding the Repressor/activator protein 1 of Candida albicans ⬇️

scientific article published on March 27, 2003

Functional characterization of CaCBF1, the Candida albicans homolog of centromere binding factor 1.

scientific article

Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans ⬇️

scientific article published on August 24, 2012

Gain-of-function mutations in the transcription factor MRR1 are responsible for overexpression of the MDR1 efflux pump in fluconazole-resistant Candida dubliniensis strains

scientific article published on 22 September 2008

Gene Deletion in Candida albicans Wild-Type Strains Using the SAT1-Flipping Strategy ⬇️

scientific article published on 01 January 2012

Generation of Viable Candida albicans Mutants Lacking the "Essential" Protein Kinase Snf1 by Inducible Gene Deletion

scientific article published on 19 August 2020

Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes

article

Genome-wide expression and location analyses of the Candida albicans Tac1p regulon.

scientific article

Global transcriptome sequencing identifies chlamydospore specific markers in Candida albicans and Candida dubliniensis

scientific article

Glutathione Utilization by Candida albicans Requires a Functional Glutathione Degradation (DUG) Pathway and OPT7, an Unusual Member of the Oligopeptide Transporter Family ⬇️

scientific article published on October 12, 2011

Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene

scientific article published in June 2002

How do fungal infections "escape" treatment? Resistance and resistance mechanisms

scientific article

Impact of manganese on biofilm formation and cell morphology of Candida parapsilosis clinical isolates with different biofilm forming abilities

scientific article published on 01 September 2019

In Vitro Activities of the Novel Investigational Tetrazoles VT-1161 and VT-1598 Compared to the Triazole Antifungals against Azole-Resistant Strains and Clinical Isolates of Candida albicans

scientific article published on 24 May 2019

Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice

scientific article published in February 2002

Inducible and Constitutive Activation of Two Polymorphic Promoter Alleles of the Candida albicans Multidrug Efflux Pump MDR1 ⬇️

scientific article published on May 21, 2012

Induction of Candida albicans drug resistance genes by hybrid zinc cluster transcription factors

scientific article published on 10 November 2014

Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis

scientific article published on 2 August 2010

Liquid growth conditions for abundant chlamydospore formation in Candida dubliniensis

scientific article published in January 2005

Loss of heterozygosity at an unlinked genomic locus is responsible for the phenotype of a Candida albicans sap4Δ sap5Δ sap6Δ mutant

scientific article published on 19 November 2010

Multiple cis-acting sequences mediate upregulation of the MDR1 efflux pump in a fluconazole-resistant clinical Candida albicans isolate

scientific article published on July 2006

Mutational analysis of the Candida albicans ammonium permease Mep2p reveals residues required for ammonium transport and signaling

scientific article published on 5 December 2008

Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains

scientific article published on 27 May 2008

New cis-Configured Aziridine-2-carboxylates as Aspartic Acid Protease Inhibitors

scientific article published on 01 January 2011

Nitrogen regulation of morphogenesis and protease secretion in Candida albicans ⬇️

scientific article published on 08 May 2011

Oligopeptide transport and regulation of extracellular proteolysis are required for growth of Aspergillus fumigatus on complex substrates but not for virulence.

scientific article

Overexpression of the MDR1 Gene Is Sufficient To Confer Increased Resistance to Toxic Compounds in Candida albicans.

scientific article published in July 2006

Overexpression of the MDR1 gene is sufficient to confer increased resistance to toxic compounds in Candida albicans

scientific article published in April 2006

Pathobiology of human-pathogenic fungi

scientific article published on 10 May 2011

Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells

scientific article (publication date: 22 November 2016)

Profile of Candida albicans-secreted aspartic proteinase elicited during vaginal infection

scientific article

Proteomic analysis of Mrr1p‐ and Tac1p‐associated differential protein expression in azole‐resistant clinical isolates of Candida albicans ⬇️

scientific article published on August 1, 2009

Proteomic analysis of azole resistance in Candida albicans clinical isolates

scientific article published on July 2004

Proteomic analysis of the oxidative stress response in Candida albicans

scientific article published in March 2007

Put3 Positively Regulates Proline Utilization in Candida albicans.

scientific article published in November 2017

Reduced PICD in Monocytes Mounts Altered Neonate Immune Response to Candida albicans

scientific article

Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans

scientific article

Regulation of multidrug resistance in pathogenic fungi

scientific article published on 07 August 2009

Regulation of white-opaque switching in Candida albicans

scientific article

Rewiring of the Ppr1 Zinc Cluster Transcription Factor from Purine Catabolism to Pyrimidine Biogenesis in the Saccharomycetaceae

scientific article published on 15 June 2016

Role of calcineurin in stress resistance, morphogenesis, and virulence of a Candida albicans wild-type strain

scientific article

Role of the Npr1 Kinase in Ammonium Transport and Signaling by the Ammonium Permease Mep2 in Candida albicans ⬇️

scientific article published on January 28, 2011

Roles of different peptide transporters in nutrient acquisition in Candida albicans

scientific article published on 2 February 2013

SAGA/ADA complex subunit Ada2 is required for Cap1- but not Mrr1-mediated upregulation of the Candida albicans multidrug efflux pump MDR1

scientific article

Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans

scientific article published in November 2008

Seminal plasma protects human spermatozoa and pathogenic yeasts from capture by dendritic cells

scientific article published on 23 February 2011

Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch

scientific article published on 8 June 2016

Targeted gene deletion in Candida albicans wild-type strains by MPAR flipping

scientific article

Tec1p-independent activation of a hypha-associated Candida albicans virulence gene during infection

scientific article published on April 2004

Tetracycline-Inducible Gene Expression and Gene Deletion in Candida albicans.

scientific article published in September 2005

Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening

scientific article published on 22 October 2007

Tetracycline-inducible gene expression and gene deletion in Candida albicans

scientific article published on August 2005

Tetracycline-inducible gene expression in Candida albicans

scientific article published on 01 January 2012

The Candida dubliniensis CdCDR1 gene is not essential for fluconazole resistance

scientific article

The Mep2p ammonium permease controls nitrogen starvation-induced filamentous growth in Candida albicans

scientific article published on 01 May 2005

The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

scientific article

The Snf1-activating kinase Sak1 is a key regulator of metabolic adaptation and in vivo fitness of Candida albicans

scientific article

The development of fluconazole resistance in Candida albicans - an example of microevolution of a fungal pathogen

scientific article published on 27 February 2016

The genetic basis of fluconazole resistance development in Candida albicans

scientific article

The protein kinase Ire1 has a Hac1-independent essential role in iron uptake and virulence of Candida albicans

scientific article published on 02 February 2022

The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans

scientific article published on 28 August 2012

The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans

scientific article

The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicans

scientific article

Transcriptional activation and increased mRNA stability contribute to overexpression of CDR1 in azole-resistant Candida albicans

scientific article published on 11 February 2008

Transcriptional analysis of the sfa determinant revealing mmRNA processing events in the biogenesis of S fimbriae in pathogenic Escherichia coli

scientific article published on January 2003

Transcriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infection

scientific article

Transport Deficiency Is the Molecular Basis of Candida albicans Resistance to Antifungal Oligopeptides.

scientific article published on 7 November 2017

Upc2p-associated differential protein expression in Candida albicans

scientific article published in October 2009

Validation of a self-excising marker in the human pathogen Aspergillus fumigatus by employing the beta-rec/six site-specific recombination system.

scientific article published on 23 July 2010

Voriconazole and multidrug resistance in Candida albicans

scientific article published on 01 March 2007

White-Opaque Switching of Candida albicans Allows Immune Evasion in an Environment-Dependent Fashion ⬇️

scientific article published on November 2, 2012

Paulina is supported by:

About Paulina

Help