List of works - Gideon Grogan

A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases

article

A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening

scientific article published in 2024

An Aminocaprolactam Racemase from Ochrobactrum anthropi with Promiscuous Amino Acid Ester Racemase Activity

scientific article published on 13 June 2018

Artificial imine reductases: developments and future directions

scientific article published in December 2020

Asymmetric Synthesis of Primary and Secondary β‐Fluoro‐arylamines using Reductive Aminases from Fungi

scientific article published on 19 March 2020

Biocatalytic Aromaticity-Breaking Epoxidation of Naphthalene and Nucleophilic Ring-Opening Reactions

scientific article published on 12 February 2021

Biocatalytic Synthesis of Moclobemide Using the Amide Bond Synthetase McbA Coupled with an ATP Recycling System

scientific article published on 30 March 2020

Biocatalytic synthesis of ribonucleoside analogues using nucleoside transglycosylase-2

scientific article published on 15 January 2025

Broad Spectrum Enantioselective Amide Bond Synthetase from Streptoalloteichus hindustanus

scientific article published on 6 January 2024

Comparing the Catalytic and Structural Characteristics of a 'Short' Unspecific Peroxygenase (UPO) Expressed in Pichia pastoris and Escherichia coli

scientific article published on 3 January 2023

Complementary specificity of unspecific peroxygenases enables access to diverse products from terpene oxygenation

scholarly article published in February 2024

Correction to "Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions"

scientific article published on 25 February 2020

Cover Feature: Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering (ChemCatChem 22/2022)

scientific article published on 7 November 2022

Discovery and Synthetic Applications of a NAD(P)H-Dependent Reductive Aminase from

scientific article published on 3 January 2025

Divergent Oxidation Reactions of E ‐ and Z ‐Allylic Primary Alcohols by an Unspecific Peroxygenase

scientific article published on 18 December 2024

Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor

scientific article published on 18 July 2023

Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering

scientific article published in 2022

Gram-scale enzymatic synthesis of 2'-deoxyribonucleoside analogues using nucleoside transglycosylase-2

scientific article published on 27 August 2024

Hemoprotein Catalyzed Oxygenations: P450s, UPOs, and Progress toward Scalable Reactions

Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions

scientific article published on 07 January 2020

Inverting the Stereoselectivity of an NADH-Dependent Imine-Reductase Variant

Mutational Analysis of Linalool Dehydratase Isomerase Suggests That Alcohol and Alkene Transformations Are Catalyzed Using Noncovalent Mechanisms

NAD(P)H‐Dependent Enzymes for Reductive Amination: Active Site Description and Carbonyl‐Containing Compound Spectrum

Oxalate Oxidase for In Situ H 2 O 2 ‐Generation in Unspecific Peroxygenase‐Catalysed Drug Oxyfunctionalisations**

scientific article published on 25 August 2022

Oxidoreductase-Catalyzed Synthesis of Chiral Amines

scientific article published on 16 October 2018

Preparative scale Achmatowicz and aza-Achmatowicz rearrangements catalyzed by Agrocybe aegerita unspecific peroxygenase

scientific article published in 2024

Preparative-Scale Biocatalytic Oxygenation of N-Heterocycles with a Lyophilized Peroxygenase Catalyst

scientific article published on 26 January 2023

Preparative‐Scale Biocatalytic Oxygenation of N ‐Heterocycles with a Lyophilized Peroxygenase Catalyst

scientific article published on 22 December 2022

Redox-reversible siderophore-based catalyst anchoring within cross-linked artificial metalloenzyme aggregates enables enantioselectivity switching

scientific article published on 21 May 2024

Reductive aminations by imine reductases: from milligrams to tons

scientific article published on 4 May 2022

Selective Oxidations of Toluenes and Benzyl Alcohols by an Unspecific Peroxygenase (UPO)

scientific article published on 6 July 2024

Snapshots of the Catalytic Cycle of the Industrial Enzyme α-Amino-ε-Caprolactam Racemase (ACLR) Observed Using X-ray Crystallography

scientific article published on 3 January 2017

Structure and Mutation of the Native Amine Dehydrogenase MATOUAmDH2

scientific article published on 7 April 2022

Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms

scientific article published in September 2023

Substrate Anchoring and Flexibility Reduction in CYP153A M.aq Leads to Highly Improved Efficiency toward Octanoic Acid

The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

scientific article published on 07 August 2018

The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

scientific article published on 7 August 2018

The Reactivity of α‐Fluoroketones with PLP Dependent Enzymes: Transaminases as Hydrodefluorinases

Two Enantiocomplementary Ephedrine Dehydrogenases from Arthrobacter sp. TS-15 with Broad Substrate Specificity

scientific article published on 29 May 2019

Unspecific Peroxygenase (UPO) can be Tuned for Oxygenation or Halogenation Activity by Controlling the Reaction pH

scientific article published on 17 May 2024

List of works by Gideon Grogan

A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases

A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening

An Aminocaprolactam Racemase from Ochrobactrum anthropi with Promiscuous Amino Acid Ester Racemase Activity

Artificial imine reductases: developments and future directions

Asymmetric Synthesis of Primary and Secondary β‐Fluoro‐arylamines using Reductive Aminases from Fungi

Biocatalytic Aromaticity-Breaking Epoxidation of Naphthalene and Nucleophilic Ring-Opening Reactions

Biocatalytic Synthesis of Moclobemide Using the Amide Bond Synthetase McbA Coupled with an ATP Recycling System

Biocatalytic synthesis of ribonucleoside analogues using nucleoside transglycosylase-2

Broad Spectrum Enantioselective Amide Bond Synthetase from Streptoalloteichus hindustanus

Comparing the Catalytic and Structural Characteristics of a 'Short' Unspecific Peroxygenase (UPO) Expressed in Pichia pastoris and Escherichia coli

Complementary specificity of unspecific peroxygenases enables access to diverse products from terpene oxygenation

Correction to "Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions"

Cover Feature: Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering (ChemCatChem 22/2022)

Discovery and Synthetic Applications of a NAD(P)H-Dependent Reductive Aminase from

Divergent Oxidation Reactions of E ‐ and Z ‐Allylic Primary Alcohols by an Unspecific Peroxygenase

Divergent Oxidation Reactions of E ‐ and Z ‐Allylic Primary Alcohols by an Unspecific Peroxygenase

Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor

Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering

Gram-scale enzymatic synthesis of 2'-deoxyribonucleoside analogues using nucleoside transglycosylase-2

Hemoprotein Catalyzed Oxygenations: P450s, UPOs, and Progress toward Scalable Reactions

Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions

Inverting the Stereoselectivity of an NADH-Dependent Imine-Reductase Variant

Mutational Analysis of Linalool Dehydratase Isomerase Suggests That Alcohol and Alkene Transformations Are Catalyzed Using Noncovalent Mechanisms

NAD(P)H‐Dependent Enzymes for Reductive Amination: Active Site Description and Carbonyl‐Containing Compound Spectrum

Oxalate Oxidase for In Situ H 2 O 2 ‐Generation in Unspecific Peroxygenase‐Catalysed Drug Oxyfunctionalisations**

Oxalate Oxidase for In Situ H 2 O 2 ‐Generation in Unspecific Peroxygenase‐Catalysed Drug Oxyfunctionalisations**

Oxidoreductase-Catalyzed Synthesis of Chiral Amines

Preparative scale Achmatowicz and aza-Achmatowicz rearrangements catalyzed by Agrocybe aegerita unspecific peroxygenase

Preparative-Scale Biocatalytic Oxygenation of N-Heterocycles with a Lyophilized Peroxygenase Catalyst

Preparative‐Scale Biocatalytic Oxygenation of N ‐Heterocycles with a Lyophilized Peroxygenase Catalyst

Redox-reversible siderophore-based catalyst anchoring within cross-linked artificial metalloenzyme aggregates enables enantioselectivity switching

Reductive aminations by imine reductases: from milligrams to tons

Selective Oxidations of Toluenes and Benzyl Alcohols by an Unspecific Peroxygenase (UPO)

Snapshots of the Catalytic Cycle of the Industrial Enzyme α-Amino-ε-Caprolactam Racemase (ACLR) Observed Using X-ray Crystallography

Structure and Mutation of the Native Amine Dehydrogenase MATOUAmDH2

Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms

Substrate Anchoring and Flexibility Reduction in CYP153A M.aq Leads to Highly Improved Efficiency toward Octanoic Acid

The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

The Reactivity of α‐Fluoroketones with PLP Dependent Enzymes: Transaminases as Hydrodefluorinases

Two Enantiocomplementary Ephedrine Dehydrogenases from Arthrobacter sp. TS-15 with Broad Substrate Specificity

Unspecific Peroxygenase (UPO) can be Tuned for Oxygenation or Halogenation Activity by Controlling the Reaction pH