List of works by Dennis T. Villareal

2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial

scientific article published on 11 July 2019

A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity

scientific article published on 17 July 2015

Absence of left ventricular and arterial adaptations to exercise in octogenarians

scientific article published on 01 November 2004

Adipocytes Expression, Body Fat and Response to Testosterone Therapy in Hypogonadal Men Vary According to Estradiol Levels

scientific article published on 04 September 2018

Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss

scientific article published on 03 July 2019

Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults

scientific article published in May 2017

Aerobic power and insulin action improve in response to endurance exercise training in healthy 77-87 yr olds.

scientific article published in January 2005

Aromatase Inhibitors Plus Weight Loss Improves the Hormonal Profile of Obese Hypogonadal Men Without Causing Major Side Effects

scientific article published on 15 May 2020

Association between high-sensitivity troponin T and cardiovascular risk in individuals with and without metabolic syndrome: The ARIC study

scientific article published on 9 December 2016

Attenuation of cardiovascular adaptations to exercise in frail octogenarians.

scientific article published on 11 July 2003

Baseline Testosterone Predicts Body Composition and Metabolic Response to Testosterone Therapy

scientific article published in 2022

Body-composition changes in the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE)-2 study: a 2-y randomized controlled trial of calorie restriction in nonobese humans.

scientific article

Bone and body composition response to testosterone therapy vary according to polymorphisms in the CYP19A1 gene

scientific article published on 19 July 2019

Bone mineral density response to caloric restriction-induced weight loss or exercise-induced weight loss: a randomized controlled trial.

scientific article published in December 2006

Caloric restriction but not exercise-induced reductions in fat mass decrease plasma triiodothyronine concentrations: a randomized controlled trial

scientific article published on June 2008

Calorie Restriction and Matched Weight Loss From Exercise: Independent and Additive Effects on Glucoregulation and the Incretin System in Overweight Women and Men

scientific article published on 15 April 2015

Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile

scientific article published on 05 June 2013

Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial

scientific article published on 27 March 2007

Circulating cytokines as determinants of weight loss-induced improvements in insulin sensitivity

scientific article published on 7 September 2016

Clinical outcomes of possible versus probable Alzheimer's disease

scientific article published in September 2003

Cognitive and neural correlates of aerobic fitness in obese older adults

scientific article published in January 2012

Combination treatment to CONQUER obesity?

scientific article published on 01 April 2011

Comparison of methods for assessing abdominal adipose tissue from magnetic resonance images

scientific article published on 01 September 2007

DHEA enhances effects of weight training on muscle mass and strength in elderly women and men.

scientific article published on 20 June 2006

Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans

scientific article

Dehydroepiandrosterone replacement therapy in older adults improves indices of arterial stiffness

scientific article

Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone

scientific article published on 25 March 2009

Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults

scientific article published on 23 April 2009

Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women

scientific article

Effect of Aerobic or Resistance Exercise, or Both, on Bone Mineral Density and Bone Metabolism in Obese Older Adults While Dieting: A Randomized Controlled Trial

scientific article published on 04 December 2019

Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density

scientific article published on 16 November 2004

Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial

scientific article published in November 2004

Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial

scientific article published on 31 August 2015

Effect of Weight Loss, Exercise, or Both on Undercarboxylated Osteocalcin and Insulin Secretion in Frail, Obese Older Adults.

scientific article published on 23 August 2017

Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults

scientific article published on 01 December 2006

Effect of weight loss and exercise on frailty in obese older adults

scientific article published on April 2006

Effect of weight loss and exercise therapy on bone metabolism and mass in obese older adults: a one-year randomized controlled trial

scientific article published on 25 March 2008

Effect of weight loss on the rate of muscle protein synthesis during fasted and fed conditions in obese older adults

scientific article published on 22 September 2011

Effect of weight loss, exercise, or both on cognition and quality of life in obese older adults

scientific article

Effective SLOPE: EffectS of Lifestyle interventions in Older PEople with obesity: a systematic review and network meta-analysis protocol

scientific article published on 07 October 2020

Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial

scientific article

Effects of Two Years of Calorie Restriction on Aerobic Capacity and Muscle Strength

scientific article published on November 2017

Effects of Weight Loss on Lean Mass, Strength, Bone, and Aerobic Capacity

scientific article

Effects of dehydroepiandrosterone on bone mineral density: what implications for therapy?

scientific article

Effects of exercise training added to ongoing hormone replacement therapy on bone mineral density in frail elderly women

scientific article published in July 2003

Effects of exercise training on bone mineral density in frail older women and men: a randomised controlled trial

scientific article published on 01 May 2004

Effects of matched weight loss from calorie restriction, exercise, or both on cardiovascular disease risk factors: a randomized intervention trial

scientific article

Effects of polymorphisms of the sex hormone-binding globulin (SHBG) gene on free estradiol and bone mineral density

scientific article published on 11 August 2009

Effects of soy protein isolate and moderate exercise on bone turnover and bone mineral density in postmenopausal women.

scientific article published on May 2007

Endothelial function after high-sugar-food ingestion improves with endurance exercise performed on the previous day.

scientific article published on July 2008

Exercise attenuates the weight-loss-induced reduction in muscle mass in frail obese older adults

scientific article published on July 2008

Exercise but not diet-induced weight loss decreases skeletal muscle inflammatory gene expression in frail obese elderly persons

scientific article published on 5 June 2008

Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip bone mineral density induced by weight loss despite decline in bone-active hormones

scientific article published on December 2011

Fat Mass Follows a U-Shaped Distribution Based on Estradiol Levels in Postmenopausal Women

scientific article published on 02 July 2018

Fat, muscle, and bone interactions in obesity and the metabolic syndrome

scientific article

High aromatase activity in hypogonadal men is associated with higher spine bone mineral density, increased truncal fat and reduced lean mass.

scientific article

Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density.

scientific article

Hypogonadal men with type 2 diabetes mellitus have smaller bone size and lower bone turnover

scientific article

Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial

scientific article published in November 2006

Increasing adiposity is associated with higher adipokine levels and lower bone mineral density in obese older adults

scientific article

Inflammatory osteolysis in diabetic neuropathic (charcot) arthropathies of the foot

scientific article published on 18 September 2008

Influence of weekend lifestyle patterns on body weight

scientific article published on 12 June 2008

Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance

scientific article published on 02 June 2009

Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle.

scientific article

Long-term effects of caloric restriction or exercise on DNA and RNA oxidation levels in white blood cells and urine in humans

scientific article published on August 2008

Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans.

scientific article

Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans

scientific article published on 13 July 2016

Low bone mass in subjects on a long-term raw vegetarian diet

scientific article

Lower extremity muscle size and strength and aerobic capacity decrease with caloric restriction but not with exercise-induced weight loss.

scientific article

MON-094 Aromatase Inhibitors and Weight Loss in Severely Obese Male Veterans with Hypogonadism: A Randomized Clinical Trial

Measurement of human mixed muscle protein fractional synthesis rate depends on the choice of amino acid tracer

scientific article published on 29 May 2007

Muscle protein synthesis response to exercise training in obese, older men and women

scientific article

Obesity in Older Adults: Technical Review and Position Statement of the American Society for Nutrition and NAASO, The Obesity Society

scientific article published on 01 November 2005

Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society

scientific article

One year of caloric restriction in humans: feasibility and effects on body composition and abdominal adipose tissue

scientific article

PREVENTING FRAILTY IN OBESE OLDER ADULTS

scientific article

Peak exercise stroke volume: associations with cardiac structure and diastolic function

scientific article published on 08 November 2002

Physical Exercise as Therapy for Frailty

scientific article

Physical frailty and body composition in obese elderly men and women.

scientific article

Plasma dehydroepiandrosterone sulfate and cardiovascular disease risk in older men and women

scientific article published on 12 August 2020

Preferential reductions in intermuscular and visceral adipose tissue with exercise-induced weight loss compared with calorie restriction

scientific article published on 20 October 2011

Reduced bone mineral density is not associated with significantly reduced bone quality in men and women practicing long-term calorie restriction with adequate nutrition.

scientific article published on 15 November 2010

Regular multicomponent exercise increases physical fitness and muscle protein anabolism in frail, obese, older adults

scientific article

STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity

scientific article published on 29 September 2020

Safety of two-year caloric restriction in non-obese healthy individuals

scientific article published on 15 March 2016

Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

scientific article published on 01 September 2018

Sarcopenic obesity: how do we treat it?

scientific article

Sex-specific effects of dehydroepiandrosterone (DHEA) on bone mineral density and body composition: A pooled analysis of four clinical trials

scientific article published on 09 December 2018

Systemic acid load from the diet affects maximal-exercise RER.

scientific article published on April 2012

TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.

scientific article

Testosterone Replacement Therapy added to Intensive Lifestyle Intervention in Older Men with Obesity and Hypogonadism

scientific article published on 22 December 2020

Testosterone and Adipokines are Determinants of Physical Performance, Strength, and Aerobic Fitness in Frail, Obese, Older Adults

scientific article

The FTO gene is associated with a paradoxically favorable cardiometabolic risk profile in frail, obese older adults

scientific article published on 24 December 2015

The effects of caloric restriction- and exercise-induced weight loss on left ventricular diastolic function.

scientific article published on 27 December 2007

Therapeutic and lifestyle approaches to obesity in older persons

scientific article published on 01 January 2019

Timing of the initial muscle biopsy does not affect the measured muscle protein fractional synthesis rate during basal, postabsorptive conditions

scientific article

Vitamin K and bone health in older adults

scientific article published on January 2014

Weight Loss, Exercise, or Both and Physical Function in Obese Older Adults

Weight Loss-Induced Reduction of Bone Mineral Density in Older Adults with Obesity

scientific article published on 01 January 2019

Weight loss and improved fitness slow down the decline in mobility in obese adults with type 2 diabetes

scientific article published on 10 July 2012

Weight loss in obese adults 65years and older: a review of the controversy

scientific article

Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training

scientific article

Weight loss therapy improves pancreatic endocrine function in obese older adults

scientific article

Weight loss, exercise, or both and physical function in obese older adults

scientific article

Weight-loss therapy improves endurance capacity in obese older adults

scientific article published on June 2008

Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.

scientific article

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