List of works - Matthias Sendler

A Syngeneic Orthotopic Murine Model of Pancreatic Adenocarcinoma in the C57/BL6 Mouse Using the Panc02 and 6606PDA Cell Lines ⬇️

scientific article published on June 30, 2011

Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis

scientific article published on 14 November 2019

Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis.

scientific article

Animal models for investigating chronic pancreatitis.

scientific article published on December 2011

Breaking down haem attenuates acute pancreatitis: a new treatment option?

scientific article published on 11 February 2011

Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis.

scientific article published on 12 May 2016

Cathepsin B-mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.

scientific article published on 24 October 2017

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.

scientific article published on 11 December 2017

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

scientific article published on 10 November 2009

Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade.

scientific article published on 23 March 2016

Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin

scientific article published on 19 November 2018

Development of Pancreatic Cancer: Targets for Early Detection and Treatment.

scientific article published on 22 June 2016

Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.

scientific article

Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice

scientific article published on 30 July 2019

Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis

scientific article published on 14 July 2016

Genetics, Cell Biology, and Pathophysiology of Pancreatitis

scientific article published on 18 January 2019

Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma

scientific article published on 06 August 2018

Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity

article

In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model

scientific article

Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function

scientific article published on 09 November 2020

Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.

scientific article published on 18 July 2014

Necrosis, Apoptosis, Necroptosis, Pyroptosis: It Matters How Acinar Cells Die During Pancreatitis.

scientific article published on 31 May 2016

Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer

scientific article published on 05 December 2011

Role of endoplasmic reticulum stress and protein misfolding in disorders of the liver and pancreas

scientific article published on 09 April 2019

Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges

scientific article published on 13 July 2017

Subdiaphragmatic vagotomy promotes tumor growth and reduces survival via TNFα in a murine pancreatic cancer model.

scientific article

TRAIL Promotes Tumor Growth in a Syngeneic Murine Orthotopic Pancreatic Cancer Model and Affects the Host Immune Response

scientific article published on 18 September 2015

The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl Channel

scientific article published on 12 July 2018

Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer.

scientific article published on 12 May 2016

List of works by Matthias Sendler

A Syngeneic Orthotopic Murine Model of Pancreatic Adenocarcinoma in the C57/BL6 Mouse Using the Panc02 and 6606PDA Cell Lines ⬇️

Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis

Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis.

Animal models for investigating chronic pancreatitis.

Breaking down haem attenuates acute pancreatitis: a new treatment option?

Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis.

Cathepsin B-mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade.

Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin

Development of Pancreatic Cancer: Targets for Early Detection and Treatment.

Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.

Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice

Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis

Genetics, Cell Biology, and Pathophysiology of Pancreatitis

Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma

Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity

In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model

Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function

Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.

Necrosis, Apoptosis, Necroptosis, Pyroptosis: It Matters How Acinar Cells Die During Pancreatitis.

Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer

Role of endoplasmic reticulum stress and protein misfolding in disorders of the liver and pancreas

Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges

Subdiaphragmatic vagotomy promotes tumor growth and reduces survival via TNFα in a murine pancreatic cancer model.

TRAIL Promotes Tumor Growth in a Syngeneic Murine Orthotopic Pancreatic Cancer Model and Affects the Host Immune Response

The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl Channel

Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer.