List of works - Christian Michel Zwaan

A Phase I study of inotuzumab ozogamicin in pediatric relapsed/refractory acute lymphoblastic leukemia (ITCC-059 study)

scientific article published on 16 October 2020

A phase 1/2, open-label, dose-escalation study of midostaurin in children with relapsed or refractory acute leukaemia

scientific article published on 11 September 2018

Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia

scientific article published on 28 November 2012

Acute leukemias in children with Down syndrome

scientific article published on February 2008

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

scientific article

Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).

scientific article

An effective modestly intensive re-induction regimen with bortezomib in relapsed or refractory paediatric acute lymphoblastic leukaemia

scientific article published on 20 April 2018

Aprepitant for paediatric chemotherapy-induced nausea and vomiting - Authors' reply

scientific article published on 27 May 2015

Aprepitant for the prevention of chemotherapy-induced nausea and vomiting in children: a randomised, double-blind, phase 3 trial

scientific article published on 12 March 2015

Aprepitant for the prevention of chemotherapy-induced nausea and vomiting in paediatric subjects: An analysis by age group

scientific article published on 12 June 2018

Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood

scientific article

CEBPA resembles Roman god Janus

Central nervous system disease in pediatric acute myeloid leukemia

scientific article

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

scientific article

Clinical implications of FLT3 mutations in pediatric AML.

scientific article published on 15 August 2006

Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

scientific article

Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia

scientific article

Cure trends in acute lymphoblastic leukemia: is it time for a revised concept of cure? ⬇️

scientific article published on May 1, 2013

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

scientific article published on 09 August 2012

Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?

scientific article published on 01 June 2006

Engagement of SIRPα inhibits growth and induces programmed cell death in acute myeloid leukemia cells

scientific article

Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia

scientific article published on 01 May 2019

Erratum: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

scholarly article published in Nature Medicine

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

scientific article

Gene expression profiles associated with pediatric relapsed AML.

scientific article

Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse

scientific article

High frequency of copy number alterations in myeloid leukaemia of Down syndrome.

scientific article

Improved survival for adolescents and young adults with Hodgkin lymphoma and continued high survival for children in the Netherlands: a population-based study during 1990-2015

scientific article published on 06 February 2020

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

scientific article

JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

scientific article published on 16 September 2017

Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening

scientific article

Low frequency of type-I and type-II aberrations in myeloid leukemia of Down syndrome, underscoring the unique entity of this disease

scientific article published in April 2012

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

scientific article published on 24 June 2016

Multimodal treatment, including interferon beta, of nasopharyngeal carcinoma in children and young adults: preliminary results from the prospective, multicenter study NPC-2003-GPOH/DCOG.

scientific article published on 22 February 2012

Neuroblastoma stage 4S: Tumor regression rate and risk factors of progressive disease

scientific article published on 17 November 2019

Neurotoxic side effects in children with refractory or relapsed T-cell malignancies treated with nelarabine based therapy

scientific article

Normal karyotype is a poor prognostic factor in myeloid leukemia of Down syndrome: a retrospective, international study.

scientific article published on 09 August 2013

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.

scientific article

PHF6 mutations in paediatric acute myeloid leukaemia

scientific article published on 21 December 2015

Patients with Chromosome 11q Deletions Are Characterized by Inborn Errors of Immunity Involving both B and T Lymphocytes

scientific article published in 2022

Pediatric Cancer Data Commons: Federating and Democratizing Data for Childhood Cancer Research

scientific article published on 18 October 2021

Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.

scientific article

Pediatric oncology as a Learning Health System: Ethical implications for best available treatment protocols

scientific article published on 16 April 2018

Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome-positive chronic myeloid leukemia

scientific article published on 01 December 2019

Phase II study of gemcitabine combined with oxaliplatin in relapsed or refractory paediatric solid malignancies: An innovative therapy for children with Cancer European Consortium Study

scientific article

Phase II study of temozolomide and topotecan (TOTEM) in children with relapsed or refractory extracranial and central nervous system tumors including medulloblastoma with post hoc Bayesian analysis: A European ITCC study

scientific article published on 08 October 2019

Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study

scientific article

Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

scientific article published on 01 March 2019

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

scientific article published on 11 June 2015

Safety and efficacy of nelarabine in children and young adults with relapsed or refractory T-lineage acute lymphoblastic leukaemia or T-lineage lymphoblastic lymphoma: results of a phase 4 study

scientific article

Subtype prediction in pediatric acute myeloid leukemia: classification using differential network rank conservation revisited

scientific article published on 23 September 2015

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions.

scientific article published on 11 December 2017

t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients

scientific article

List of works by Christian Michel Zwaan

A Phase I study of inotuzumab ozogamicin in pediatric relapsed/refractory acute lymphoblastic leukemia (ITCC-059 study)

A phase 1/2, open-label, dose-escalation study of midostaurin in children with relapsed or refractory acute leukaemia

Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia

Acute leukemias in children with Down syndrome

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).

An effective modestly intensive re-induction regimen with bortezomib in relapsed or refractory paediatric acute lymphoblastic leukaemia

Aprepitant for paediatric chemotherapy-induced nausea and vomiting - Authors' reply

Aprepitant for the prevention of chemotherapy-induced nausea and vomiting in children: a randomised, double-blind, phase 3 trial

Aprepitant for the prevention of chemotherapy-induced nausea and vomiting in paediatric subjects: An analysis by age group

Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood

CEBPA resembles Roman god Janus

Central nervous system disease in pediatric acute myeloid leukemia

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

Clinical implications of FLT3 mutations in pediatric AML.

Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia

Cure trends in acute lymphoblastic leukemia: is it time for a revised concept of cure? ⬇️

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?

Engagement of SIRPα inhibits growth and induces programmed cell death in acute myeloid leukemia cells

Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia

Erratum: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

Gene expression profiles associated with pediatric relapsed AML.

Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse

High frequency of copy number alterations in myeloid leukaemia of Down syndrome.

Improved survival for adolescents and young adults with Hodgkin lymphoma and continued high survival for children in the Netherlands: a population-based study during 1990-2015

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening

Low frequency of type-I and type-II aberrations in myeloid leukemia of Down syndrome, underscoring the unique entity of this disease

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

Multimodal treatment, including interferon beta, of nasopharyngeal carcinoma in children and young adults: preliminary results from the prospective, multicenter study NPC-2003-GPOH/DCOG.

Neuroblastoma stage 4S: Tumor regression rate and risk factors of progressive disease

Neurotoxic side effects in children with refractory or relapsed T-cell malignancies treated with nelarabine based therapy

Normal karyotype is a poor prognostic factor in myeloid leukemia of Down syndrome: a retrospective, international study.

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.

PHF6 mutations in paediatric acute myeloid leukaemia

Patients with Chromosome 11q Deletions Are Characterized by Inborn Errors of Immunity Involving both B and T Lymphocytes

Pediatric Cancer Data Commons: Federating and Democratizing Data for Childhood Cancer Research

Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.

Pediatric oncology as a Learning Health System: Ethical implications for best available treatment protocols

Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome-positive chronic myeloid leukemia

Phase II study of gemcitabine combined with oxaliplatin in relapsed or refractory paediatric solid malignancies: An innovative therapy for children with Cancer European Consortium Study

Phase II study of temozolomide and topotecan (TOTEM) in children with relapsed or refractory extracranial and central nervous system tumors including medulloblastoma with post hoc Bayesian analysis: A European ITCC study

Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study

Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

Safety and efficacy of nelarabine in children and young adults with relapsed or refractory T-lineage acute lymphoblastic leukaemia or T-lineage lymphoblastic lymphoma: results of a phase 4 study

Subtype prediction in pediatric acute myeloid leukemia: classification using differential network rank conservation revisited

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions.

t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients