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List of works by Keith A Houck

Acidic fibroblast growth factor (HBGF-1) stimulates DNA synthesis in primary rat hepatocyte cultures ⬇️

scientific article published on 01 April 1990

An "EAR" on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure-Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters.

scientific article

An evaluation of 25 selected ToxCast chemicals in medium-throughput assays to detect genotoxicity

scientific article published on 23 December 2014

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

scientific article

Characterization of physicochemical properties of nanomaterials and their immediate environments in high‐throughput screening of nanomaterial biological activity ⬇️

scientific article published on May 9, 2013

Computational toxicology--a state of the science mini review

scientific article published on 07 December 2007

Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays.

scientific article

Control of hepatocyte replication by two serum factors ⬇️

scientific article published on 01 October 1984

Development of a quantitative morphological assessment of toxicant-treated zebrafish larvae using brightfield imaging and high-content analysis

scientific article published on 29 February 2016

Dosimetric anchoring of in vivo and in vitro studies for perfluorooctanoate and perfluorooctanesulfonate

scientific article published on 17 September 2013

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms ⬇️

scientific article published on December 25, 1992

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

scientific article

Environmental surveillance and monitoring--The next frontiers for high-throughput toxicology

scientific article

Evaluating biological activity of compounds by transcription factor activity profiling

scientific article published on 26 September 2018

Hepatopoietins A and B and hepatocyte growth ⬇️

scientific article published on 01 May 1991

High-Throughput Screening to Predict Chemical-Assay Interference

scientific article published on 04 March 2020

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme

scientific article published on 22 April 2014

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

scientific article

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

scientific article published on 16 July 2010

Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential ⬇️

scientific article published on July 25, 2011

Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment

scientific article

Molecular and biological properties of the vascular endothelial growth factor family of proteins

scientific article published on February 1, 1992

Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

scientific article

Potential Toxicity of Complex Mixtures in Surface Waters from a Nationwide Survey of United States Streams: Identifying in Vitro Bioactivities and Causative Chemicals

scientific article published on 21 December 2018

Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses

scientific article published on 10 July 2014

Primary Cell Phenotypic Screening Illuminates ADRs and AOPs

scientific article published in July 2017

Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor

scientific article published on 26 September 2014

Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates.

scientific article

The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them

scientific article published on 09 March 2020

The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency

scientific article published on 01 June 2019

The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology

scientific article published on 03 November 2020

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

scientific article published on February 21, 1992

The vascular endothelial growth factor family of polypeptides ⬇️

scientific article published on November 1, 1991

Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries

scientific article published on 15 February 2016

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

scientific article (publication date: 15 August 2016)

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure

scientific article

Using nuclear receptor activity to stratify hepatocarcinogens

scientific article

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