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List of works by Rolf Brekken

A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity

scientific article

APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice

scientific article published on 31 July 2019

Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer

scientific article published on 23 January 2018

Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer.

scientific article published on 2 April 2019

Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer

scientific article published in 2022

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

scientific article published on 23 July 2019

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

preprint posted on 4 February 2019

Concentration-dependent early anti-vascular and anti-tumor effects of itraconazole in non-small cell lung cancer

scientific article published on 26 August 2020

Diagnostic and Prognostic Markers for Pancreatitis and Pancreatic Ductal Adenocarcinoma

scientific article published on 16 June 2024

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.

scientific article published on 25 September 2017

Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition

scientific article published on 26 November 2019

GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer

scientific article

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

scientific article published on 28 May 2019

Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma

scientific article published on 03 October 2018

Immune Checkpoint Inhibition is Safe and Effective for Liver Cancer Prevention in a Mouse Model of Hepatocellular Carcinoma

scientific article published on 24 August 2020

Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues

scientific article published on 03 December 2018

Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction

scientific article published on 11 June 2018

MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting

scientific article

Matrix control of pancreatic cancer: New insights into fibronectin signaling

scientific article

Pancreatic cancer stroma: an update on therapeutic targeting strategies

scientific article published on 11 May 2020

Pleiotrophin drives a prometastatic immune niche in breast cancer

scientific article published in 2023

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

scientific article (publication date: 19 January 2017)

TIMs, TAMs, and PS- antibody targeting: implications for cancer immunotherapy

scientific article published on 22 February 2020

Targeting TGFβR2-mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer

scientific article published on 14 October 2019

Woodchuck VEGF (wVEGF) characteristics: Model for angiogenesis and human hepatocellular carcinoma directed therapies

scientific article published on 13 November 2018

ΔNp63 regulated epithelial-to-mesenchymal transition state heterogeneity confers a leader-follower relationship that drives collective invasion

scientific article published on 13 July 2020

β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis

scientific article published on 14 January 2019

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