List of works by Daniel H van Raalte

About the gut microbiome as a pharmacological target in atherosclerosis

scientific article published on 18 June 2015

Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men.

scientific article published on 2 February 2010

Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial

scientific article published on April 2016

Biliary effects of liraglutide and sitagliptin, a 12-week randomized placebo-controlled trial in type 2 diabetes patients.

scientific article published on 23 July 2016

Cardiovascular, renal and gastrointestinal effects of incretin-based therapies: an acute and 12-week randomised, double-blind, placebo-controlled, mechanistic intervention trial in type 2 diabetes

scientific article

Causality of small and large intestinal microbiota in weight regulation and insulin resistance

scientific article

Comment on Thomsen et al. Incretin-Based Therapy and Risk of Acute Pancreatitis: A Nationwide Population-Based Case-Control Study. Diabetes Care 2015;38:1089-1098.

scientific article

Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study.

scientific article

Does dipeptidyl peptidase-4 inhibition prevent the diabetogenic effects of glucocorticoids in men with the metabolic syndrome? A randomized controlled trial

scientific article published on 4 February 2014

Does glucagon-like peptide-1 receptor agonist therapy add value in the treatment of type 2 diabetes? Focus on exenatide

scientific article published in December 2009

Ectopic Fat Storage in the Pancreas, Liver, and Abdominal Fat Depots: Impact on β-Cell Function in Individuals with Impaired Glucose Metabolism

scientific article published on November 17, 2010

Effect of 3 Years of Treatment With Exenatide on Postprandial Glucagon Levels

scientific article published on 30 December 2015

Effect of immediate and prolonged GLP-1 receptor agonist administration on uric acid and its kidney clearance: post-hoc analyses of four clinical trials

scientific article published on 17 January 2018

Effects of DPP-4 Inhibitor Linagliptin Versus Sulfonylurea Glimepiride as Add-on to Metformin on Renal Physiology in Overweight Patients With Type 2 Diabetes (RENALIS): A Randomized, Double-Blind Trial

scientific article published on 08 September 2020

Effects of DPP-4 inhibitor linagliptin versus sulfonylurea glimepiride on systemic haemodynamics in overweight patient with type 2 diabetes: a secondary analysis of an 8-week randomized controlled double-blind trial

scientific article published on 01 June 2020

Effects of dapagliflozin and gliclazide on the cardiorenal axis in people with type 2 diabetes

scientific article published on 06 June 2020

Erratum. SGLT2 Inhibitors in Combination Therapy: From Mechanisms to Clinical Considerations in Type 2 Diabetes Management. Diabetes Care 2018;41:1543-1556

scientific article published on 20 August 2019

Exenatide acutely increases heart rate in parallel with augmented sympathetic nervous system activation in healthy overweight males

scientific article

GLP-1 Receptor Agonist Exenatide Increases Capillary Perfusion Independent of Nitric Oxide in Healthy Overweight Men.

scientific article published on 23 April 2015

GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes

scientific article published on 4 September 2017

GLP-1 based therapies: clinical implications for gastroenterologists.

scientific article

GLP-1 receptor agonists, CKD, and eGFR trajectory

scientific article published on 01 October 2018

GLP-1-Based Therapies Have No Microvascular Effects in Type 2 Diabetes Mellitus: An Acute and 12-Week Randomized, Double-Blind, Placebo-Controlled Trial

scientific article

Glomerular Hyperfiltration in Diabetes: Mechanisms, Clinical Significance, and Treatment

scientific article published on 31 January 2017

Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?

scientific article published on 6 May 2016

Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans.

scientific article published on 7 January 2011

Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial

scientific article published on 11 August 2013

Glucolipotoxicity and beta cells in type 2 diabetes mellitus: target for durable therapy?

scientific article published on August 2011

Glucosuria Interferes With Measurement of Effective Renal Plasma Flow Using para-Aminohippuric Acid, With a Focus on SGLT2 Inhibitors

scientific article published on 06 September 2020

Heart rate acceleration with GLP-1 receptor agonists in type 2 diabetes patients: an acute and 12-week randomised, double-blind, placebo-controlled trial.

scientific article

High Prevalence of Intraductal Papillary Mucinous Neoplasms in Type 2 Diabetes Mellitus Patients

scientific article published on 01 January 2020

Iloprost infusion prevents the insulin-induced reduction in skeletal muscle microvascular blood volume but does not enhance peripheral glucose uptake in type 2 diabetic patients

scientific article published on 27 July 2018

Improving glycaemic control in type 2 diabetes: Stimulate insulin secretion or provide beta-cell rest?

scientific article published on 14 March 2017

Intestinal Ralstonia pickettii augments glucose intolerance in obesity

scientific article

Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?

scientific article published on 17 November 2012

Light therapy for better mood and insulin sensitivity in patients with major depression and type 2 diabetes: a randomised, double-blind, parallel-arm trial

scientific article published on 24 July 2015

Malignant cutaneous lesions

scientific article published on 13 August 2015

Metabolic changes in type 2 diabetes are reflected in peripheral blood cells, revealing aberrant cytotoxicity, a viral signature, and hypoxia inducible factor activity

scientific article published on 9 May 2015

Michaela Diamant, 11 April 1962-9 April 2014.

scientific article published on 6 May 2014

Pancreatic Effects of Liraglutide or Sitagliptin in Overweight Patients With Type 2 Diabetes: A 12-Week Randomized, Placebo-Controlled Trial.

scientific article

Pancreatic Steatosis Is Not Associated With Exocrine Pancreatic Function in Overweight Type 2 Diabetes Patients.

scientific article

Pancreatic steatosis in humans: cause or marker of lipotoxicity?

scientific article published on July 2010

Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future

scientific article

Plasma uric acid and renal haemodynamics in type 2 diabetes patients

scientific article published on 12 September 2019

Pleiotropic effects of type 2 diabetes management strategies on renal risk factors.

scientific article

Postprandial renal haemodynamic effect of lixisenatide vs once-daily insulin-glulisine in patients with type 2 diabetes on insulin-glargine: An 8-week, randomised, open-label trial

scientific article published on 27 April 2017

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

scientific article published on 13 June 2011

Renal Effects of DPP-4 Inhibitor Sitagliptin or GLP-1 Receptor Agonist Liraglutide in Overweight Patients With Type 2 Diabetes: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial

scientific article published on September 2016

Renal hemodynamic and protective effects of renoactive drugs in type 2 diabetes: interaction with SGLT2 inhibitors

scientific article published on 06 December 2020

Renal hemodynamic effects of sodium-glucose cotransporter 2 inhibitors in hyperfiltering people with type 1 diabetes and people with type 2 diabetes and normal kidney function

scientific article published on 01 April 2020

Renal outcomes in CVOTs: keep calm and carry on

scientific article published on 21 June 2018

Renal sinus fat and renal hemodynamics: a cross-sectional analysis

scientific article published on 31 August 2019

Renoprotection in LEADER and EMPA-REG OUTCOME

scientific article published on 01 October 2016

Renoprotection in diabetic kidney disease: can incretin-based therapies deliver?

scientific article published on 01 January 2020

Role of Insulin-Stimulated Adipose Tissue Perfusion in the Development of Whole-Body Insulin Resistance

scientific article published on 26 January 2017

Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction

scientific article published on 9 February 2017

SGLT2 Inhibition in the Diabetic Kidney-From Mechanisms to Clinical Outcome.

scientific article

SGLT2 inhibition versus sulfonylurea treatment effects on electrolyte and acid-base balance: secondary analysis of a clinical trial reaching glycemic equipoise

scientific article published on 18 November 2020

SGLT2 inhibition: a new era in renoprotective medicine?

scientific article published on 27 June 2017

SGLT2 inhibitors' interaction with other renoactive drugs in type 2 diabetes patients: still a lot to learn

scientific article published on 01 August 2019

Sarcoidosis-related hypercalcaemia due to production of parathyroid hormone-related peptide

scientific article published on 9 July 2015

Sodium glucose cotransporter (SGLT)-2 inhibitors: Do we need them for glucose-lowering, for cardiorenal protection or both?

scientific article published on 01 April 2019

The authors reply

scientific article published on 01 April 2020

The effect of alogliptin and pioglitazone combination therapy on various aspects of β-cell function in patients with recent-onset type 2 diabetes

scientific article published on 8 March 2014

The effects of GLP-1 based therapies on postprandial haemodynamics: Two randomised, placebo-controlled trials in overweight type 2 diabetes patients.

scientific article published on 27 December 2016

The effects of dapagliflozin on cardio-renal risk factors in patients with type 2 diabetes with or without renin-angiotensin system inhibitor treatment: a post hoc analysis

scientific article published on 14 December 2019

The osteoblast: Linking glucocorticoid-induced osteoporosis and hyperglycaemia? A post-hoc analysis of a randomised clinical trial

scientific article published on 03 May 2018

The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trial

scientific article published on 10 October 2019

Twelve week liraglutide or sitagliptin does not affect hepatic fat in type 2 diabetes: a randomised placebo-controlled trial.

scientific article published on 15 September 2016

Uncomplicated human type 2 diabetes is associated with meal-induced blood pressure lowering and cardiac output increase

scientific article published on 7 October 2014

Understanding EMPA-REG OUTCOME

scientific article published on 01 December 2015