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List of works by Conchita Vens

Acute Hypoxia Profile is a Stronger Prognostic Factor than Chronic Hypoxia in Advanced Stage Head and Neck Cancer Patients.

scientific article

Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation

scientific article published on 01 January 2019

Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation

scientific article published on 30 January 2008

Comparative genomic analysis of oral versus laryngeal and pharyngeal cancer

scientific article published on 13 April 2018

Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy

scientific article published on 22 May 2020

Correction: Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy

scientific article published on 28 July 2020

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity

scientific article published on 03 August 2018

Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC

scientific article published on 12 September 2019

Epithelial-to-mesenchymal transition is a prognostic marker for patient outcome in advanced stage HNSCC patients treated with chemoradiotherapy

scientific article published on 12 May 2020

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells

scientific article published on 13 May 2015

Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma.

scientific article published on 6 April 2018

Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy.

scientific article

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

scientific article

Histopathology-derived modeling of prostate cancer tumor control probability: Implications for the dose to the tumor and the gland

scientific article published on 16 February 2016

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

scientific article published on 19 May 2017

Improved pharmacodynamic (PD) assessment of low dose PARP inhibitor PD activity for radiotherapy and chemotherapy combination trials

scientific article published on 14 November 2017

Involvement of DNA polymerase beta in repair of ionizing radiation damage as measured by in vitro plasmid assays

scientific article published on September 2007

Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells

scientific article published on December 2007

Mechanism of cell killing after ionizing radiation by a dominant negative DNA polymerase beta

scientific article

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study

scientific article published on 8 January 2014

New challenge of developing combined radio-drug therapy

scientific article published on 01 June 2014

Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective

scientific article published on 18 February 2010

Ovarian cancer-derived copy number alterations signatures are prognostic in chemoradiotherapy-treated head and neck squamous cell carcinoma

scientific article published on 13 March 2020

Phase 1 and pharmacological study of olaparib in combination with high-dose radiotherapy with and without concurrent cisplatin for non-small cell lung cancer

scientific article published on 01 December 2020

Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons ⬇️

scientific article published on August 6, 2012

Radiosensitization by a dominant negative to DNA polymerase beta is DNA polymerase beta-independent and XRCC1-dependent

scientific article published in August 2005

Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status

scientific article

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

scientific article published on 20 March 2015

Role for DNA polymerase beta in response to ionizing radiation

scientific article published on 28 November 2006

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association

scientific article published in PLoS ONE

Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2).

scientific article published on 7 January 2008

Strategies to improve radiotherapy with targeted drugs

scientific article published on April 2011

Targeted Radiosensitization of Cells Expressing Truncated DNA Polymerase β ⬇️

scientific article published on October 26, 2010

Targeting base excision repair as a sensitization strategy in radiotherapy

scientific article published on October 2010

The role of DNA polymerase beta in determining sensitivity to ionizing radiation in human tumor cells

scientific article published on July 2002

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.

scientific article

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