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List of works by Zhe-Sheng Chen

AST1306, a potent EGFR inhibitor, antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance

scientific article published on 18 April 2014

An Active Efflux System for Heavy Metals in Cisplatin-Resistant Human KB Carcinoma Cells ⬇️

scientific article published on 01 May 1998

BMS-599626, a Highly Selective Pan-HER Kinase Inhibitor, Antagonizes ABCG2-Mediated Drug Resistance

scientific article published on 03 September 2020

CDX2 Stimulates the Proliferation of Porcine Intestinal Epithelial Cells by Activating the mTORC1 and Wnt/β-Catenin Signaling Pathways.

scientific article published on 18 November 2017

Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer

scientific article published on 02 September 2020

Chemical molecular-based approach to overcome multidrug resistance in cancer by targeting P-glycoprotein (P-gp)

scientific article published on 12 October 2020

Chk1 Inhibitor MK-8776 Restores the Sensitivity of Chemotherapeutics in P-glycoprotein Overexpressing Cancer Cells ⬇️

scientific article published on 22 August 2019

Ciprofloxacin Enhances the Chemosensitivity of Cancer Cells to ABCB1 Substrates ⬇️

scientific article published on 11 January 2019

Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy

scientific article published on 01 May 2019

Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein

scientific article

Contribution of Abcc10 (Mrp7) to In Vivo Paclitaxel Resistance as Assessed in Abcc10−/− Mice ⬇️

scientific article published on May 15, 2011

Current Advances and Outlook in Gastric Cancer Chemoresistance: A Review

scientific article published in 2022

Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters

scientific article published on 10 January 2018

Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid

scientific article

Dual TTK/CLK2 inhibitor, CC-671, selectively antagonizes ABCG2-mediated multidrug resistance in lung cancer cells

scientific article published on 01 June 2020

Effect of Y6, an epigallocatechin gallate derivative, on reversing doxorubicin drug resistance in human hepatocellular carcinoma cells

scientific article published on 7 March 2017

Enhanced sorption of radiocobalt from water by Bi(III) modified montmorillonite: A novel adsorbent ⬇️

scientific article published on May 10, 2011

Epitranscriptomics and epiproteomics in cancer drug resistance: therapeutic implications

scientific article published on 08 September 2020

Establishment and characterization of arsenic trioxide resistant KB/ATO cells

scientific article published on 28 April 2017

Evodiamine Suppresses ABCG2 Mediated Drug Resistance by Inhibiting p50/p65 NF-κB Pathway in Colorectal Cancer.

scientific article published on 29 February 2016

Exploring naturally occurring ivy nanoparticles as an alternative biomaterial

scientific article published on 26 July 2015

GSK1904529A, a Potent IGF-IR Inhibitor, Reverses MRP1-Mediated Multidrug Resistance.

scientific article

Ganoderma lucidum derived ganoderenic acid B reverses ABCB1-mediated multidrug resistance in HepG2/ADM cells

scientific article

IKK inhibition increases bortezomib effectiveness in ovarian cancer

scientific article

Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2.

scientific article

Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing

scientific article published on 08 October 2020

Identification of new potent anticancer derivatives through simplifying the core structure and modification on their 14- hydroxyl group from oridonin

scientific article published in 2022

In vitro, in vivo and ex vivo characterization of ibrutinib: a potent inhibitor of the efflux function of the transporter MRP1.

scientific article

Increased sensitivity to vincristine of MDR cells by the leukotriene D4 receptor antagonist, ONO-1078 ⬇️

scientific article published on August 14, 1998

Lipid-Saporin Nanoparticles for the Intracellular Delivery of Cytotoxic Protein to Overcome ABC Transporter-Mediated Multidrug Resistance In Vitro and In Vivo

scientific article published on 21 February 2020

Long non-coding RNAs regulate drug resistance in cancer

scientific article published on 12 March 2020

Modulating the function of ABCB1: in vitro and in vivo characterization of sitravatinib, a tyrosine kinase inhibitor

scientific article published on 11 June 2020

Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1.

scientific article

Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases ⬇️

scientific article published on August 1, 2011

N6-methyladenosine regulated FGFR4 attenuates ferroptotic cell death in recalcitrant HER2-positive breast cancer

scientific article published on 13 May 2022

Novel hybrids of natural oridonin-bearing nitrogen mustards as potential anticancer drug candidates

scientific article

Oncosis-inducing cyclometalated iridium(iii) complexes

scientific article published on 03 May 2018

Overcoming multidrug resistance by knockout of ABCB1 gene using CRISPR/Cas9 system in SW620/Ad300 colorectal cancer cells

scientific article published in 2021

Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells

scientific article published on 19 February 2020

PBA2, a novel inhibitor of imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia

scientific article published on 05 October 2016

PIK3CA mutations-mediated downregulation of circLHFPL2 inhibits colorectal cancer progression via upregulating PTEN

scientific article published on 26 May 2022

Paclitaxel Through the Ages of Anticancer Therapy: Exploring Its Role in Chemoresistance and Radiation Therapy

scientific article

Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs

scientific article

Repositioning of Tyrosine Kinase Inhibitors as Antagonists of ATP-Binding Cassette Transporters in Anticancer Drug Resistance

scientific article

Reversal of Heavy Metal Resistance in Multidrug-Resistant Human KB Carcinoma Cells ⬇️

scientific article published on July 30, 1997

Reversal of MRP-mediated vincristine resistance in KB cells by buthionine sulfoximine in combination with PAK-104P ⬇️

scientific article published on July 3, 1998

Selective reversal of BCRP-mediated MDR by VEGFR-2 inhibitor ZM323881.

scientific article published on 24 February 2017

Special Issue: Natural Products: Anticancer and Beyond.

scientific article published on 23 May 2018

Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5-<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators

scientific article published on 05 December 2020

Suppression of ABCG2 mediated MDR in vitro and in vivo by a novel inhibitor of ABCG2 drug transport

scientific article published on 25 April 2017

Tea nanoparticle, a safe and biocompatible nanocarrier, greatly potentiates the anticancer activity of doxorubicin

scientific article published on 21 December 2015

Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression

scientific article published on 30 November 2019

The PI3K subunits, P110α and P110β are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer

scientific article published on 17 January 2020

The Phosphodiesterase-5 Inhibitor Vardenafil Is a Potent Inhibitor of ABCB1/P-Glycoprotein Transporter ⬇️

scientific article published on April 28, 2011

The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decade

scientific article published on 10 December 2014

Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance

scientific article published on 12 January 2020

Tyrosine kinase inhibitors as modulators of ABC transporter-mediated drug resistance ⬇️

scientific article published on February 9, 2012

miR200c attenuates P-gp-mediated MDR and metastasis by targeting JNK2/c-Jun signaling pathway in colorectal cancer

scientific article published on 9 September 2014

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