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List of works by Margaret A Shipp

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma

scientific article published on 10 August 2020

A possible immunoregulatory function for [Met]-enkephalin-Arg6-Phe7 involving human and invertebrate granulocytes

scientific article published on 01 February 1991

A roadmap for discovery and translation in lymphoma.

scientific article published on March 2015

A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease.

scientific article

AP1-dependent galectin-1 expression delineates classical hodgkin and anaplastic large cell lymphomas from other lymphoid malignancies with shared molecular features

scientific article published on 01 June 2008

Aberrant expression of the dendritic cell marker TNFAIP2 by the malignant cells of Hodgkin lymphoma and primary mediastinal large B-cell lymphoma distinguishes these tumor types from morphologically and phenotypically similar lymphomas.

scientific article published on October 2011

Abstract A38: <i>Cd70</i> genetic perturbation limits the development of an effective CD8+ T-cell immune response to <i>Bcl6</i>-driven diffuse large B-cell lymphoma

scientific article published in 2022

Advances in the biology and therapy of diffuse large B-cell lymphoma: moving toward a molecularly targeted approach

scientific article

Alternatively spliced CD44 transcripts in diffuse large-cell lymphomas: characterization and comparison with normal activated B cells and epithelial malignancies

scientific article published on 01 December 1993

An open-label, multicohort Phase Ib trial of pembrolizumab (MK-3475) for advanced hematologic malignancies: KEYNOTE-013.

scientific article published on 4 November 2015

Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity

scientific article

BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate

scientific article

BAL1 and Its Partner E3 Ligase, BBAP, Link Poly(ADP-Ribose) Activation, Ubiquitylation, and Double-Strand DNA Repair Independent of ATM, MDC1, and RNF8 ⬇️

scientific article published on December 10, 2012

BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response

scientific article

BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt.

scientific article published on 23 October 2009

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms

scientific article

BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

scientific article

CD10 (CALLA)/neutral endopeptidase 24.11 modulates inflammatory peptide-induced changes in neutrophil morphology, migration, and adhesion proteins and is itself regulated by neutrophil activation

scientific article published on 01 October 1991

CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas

scientific article published on 30 August 2019

Case records of the Massachusetts General Hospital. Case 12-2005. A 30-year-old woman with a mediastinal mass

scientific article published in April 2005

Classical Hodgkin Lymphoma with Reduced β2M/MHC Class I Expression Is Associated with Inferior Outcome Independent of 9p24.1 Status

scientific article published on 13 October 2016

Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib

scientific article published on 7 August 2003

Combined Anti-VEGF and Anti-CTLA-4 Therapy Elicits Humoral Immunity to Galectin-1 Which Is Associated with Favorable Clinical Outcomes.

scientific article published on 4 May 2017

Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): direct evidence by cDNA transfection analysis

scientific article

Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy

scientific article published on 23 January 2012

Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets.

scientific article published on 21 October 2016

Differential expression of nuclear proto-oncogenes in T cells triggered with mitogenic and nonmitogenic T3 and T11 activation signals

scientific article published on 01 October 1987

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning ⬇️

scientific article published on January 1, 2002

Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease

scientific article published on 15 January 2016

Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.

scientific article

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

scientific article

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

scientific article

Downregulation of enkephalin-mediated inflammatory responses by CDl0/neutral endopeptidase 24.11

scientific article published in Nature

Early restaging gallium scans predict outcome in poor-prognosis patients with aggressive non-Hodgkin's lymphoma treated with high-dose CHOP chemotherapy

scientific article published on 01 April 1997

Expression of TRAF1 and nuclear c-Rel distinguishes primary mediastinal large cell lymphoma from other types of diffuse large B-cell lymphoma

scientific article published on 01 January 2007

Expression of programmed cell death 1 ligand 2 (PD-L2) is a distinguishing feature of primary mediastinal (thymic) large B-cell lymphoma and associated with PDCD1LG2 copy gain

scientific article published on December 2014

FAS Death Domain Deletions and Cellular FADD-like Interleukin 1 Converting Enzyme Inhibitory Protein (Long) Overexpression: Alternative Mechanisms for Deregulating the Extrinsic Apoptotic Pathway in Diffuse Large B-Cell Lymphoma Subtypes

scientific article published on 01 June 2006

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas

scientific journal article

GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis

scientific article

Galectin-1 serum levels reflect tumor burden and adverse clinical features in classical Hodgkin lymphoma ⬇️

scientific article published on February 26, 2013

Genetic Basis for PD-L1 Expression in Squamous Cell Carcinomas of the Cervix and Vulva

scientific article

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

scientific article published on 01 December 2019

Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion

scientific article published on 01 December 2019

Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors

scientific article

Heterogeneous CD52 expression among hematologic neoplasms: implications for the use of alemtuzumab (CAMPATH-1H)

scientific article published on 01 December 2006

High dose CHOP: a phase II study of initial treatment in aggressive non-Hodgkin lymphoma. Cancer and Leukemia Group B 9351.

scientific article

High-dose CHOP as initial therapy for patients with poor-prognosis aggressive non-Hodgkin's lymphoma: a dose-finding pilot study

scientific article

Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas

scientific article

Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop

scientific article published on 19 May 2016

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

scientific article

Inhibition of CD10/neutral endopeptidase 24.11 promotes B-cell reconstitution and maturation in vivo

scientific article

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

scientific article

Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma.

scientific article published on September 2012

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.

scientific article

Interaction of immunoactive monokines (interleukin 1 and tumor necrosis factor) in the bivalve mollusc Mytilus edulis

scientific article

International Consensus Conference on high-dose therapy with hematopoietic stem-cell transplantation in aggressive non-Hodgkin's lymphomas: report of the jury.

scientific article

Lack of IKBA coding region mutations in primary mediastinal large B-cell lymphoma and the host response subtype of diffuse large B-cell lymphoma

article

Large-cell and immunoblastic lymphoma of the mediastinum: prognostic features and treatment outcome in 57 patients

scientific article published on 01 July 1993

MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.

scientific article

Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma

scientific article published on 2 February 2018

Mass cytometry of Hodgkin lymphoma reveals a CD4+ regulatory T-cell-rich and exhausted T-effector microenvironment

scientific article published on 07 June 2018

Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma ⬇️

scientific article published on October 16, 2012

Molecular classification of MYC-driven B-cell lymphomas by targeted gene expression profiling of fixed biopsy specimens.

scientific article published on 7 November 2014

Molecular cloning of the common acute lymphoblastic leukemia antigen (CALLA) identifies a type II integral membrane protein

scientific article

Molecular diagnostics

scientific article published on 01 January 2003

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

article

Molecular signatures define new rational treatment targets in large B-cell lymphomas

scientific article published on January 2007

Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

Murine common acute lymphoblastic leukemia antigen (CD10 neutral endopeptidase 24.11). Molecular characterization, chromosomal localization, and modeling of the active site ⬇️

scientific article published on May 1, 1992

NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes

scientific article

NLRC5/MHC class I transactivator is a target for immune evasion in cancer

scientific article published on 09 May 2016

New concepts in treatment approaches and prognostic factors in aggressive NHL

scientific article published on 01 February 2006

Nivolumab for Newly Diagnosed Advanced-Stage Classic Hodgkin Lymphoma: Safety and Efficacy in the Phase II CheckMate 205 Study

scientific article published on 21 May 2019

Nivolumab for Relapsed/Refractory Classic Hodgkin Lymphoma After Failure of Autologous Hematopoietic Cell Transplantation: Extended Follow-Up of the Multicohort Single-Arm Phase II CheckMate 205 Trial

article

Nivolumab for Relapsed/Refractory Diffuse Large B-Cell Lymphoma in Patients Ineligible for or Having Failed Autologous Transplantation: A Single-Arm, Phase II Study

scientific article published on 08 January 2019

Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial

scientific article

Nivolumab in Patients With Relapsed or Refractory Hematologic Malignancy: Preliminary Results of a Phase Ib Study

scientific article

No evidence for the JAK2 (V617F) or JAK2 exon 12 mutations in primary mediastinal large B-cell lymphoma

scientific article published on September 2009

Organization of the gene encoding common acute lymphoblastic leukemia antigen (neutral endopeptidase 24.11): multiple miniexons and separate 5' untranslated regions

scientific article

PD-1 blockade for diffuse large B-cell lymphoma after autologous stem cell transplantation

scientific article published on 01 January 2020

PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma

scientific article (publication date: 22 January 2015)

PD-1 blockade with nivolumab in relapsed/refractory primary central nervous system and testicular lymphoma

scientific article published on 29 March 2017

PD-1 blockade with pembrolizumab for classical Hodgkin lymphoma after autologous stem cell transplantation

scientific article published on 05 April 2019

PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies ⬇️

scientific article published on May 14, 2013

PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome

scientific article

Patterns of relapse in large-cell lymphoma patients with bulk disease: implications for the use of adjuvant radiation therapy

scientific article published on 01 May 1989

Pembrolizumab in Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma

scientific article published on 14 October 2019

Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087

scientific article published on 13 August 2019

Pembrolizumab monotherapy in patients with primary refractory classical hodgkin lymphoma who relapsed after salvage autologous stem cell transplantation and/or brentuximab vedotin therapy: KEYNOTE-087 subgroup analysis

scientific article published on 06 January 2020

Phase I trial of the matrix metalloproteinase inhibitor marimastat combined with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer

scientific article published in May 2005

Phase II Study of the Efficacy and Safety of Pembrolizumab for Relapsed/Refractory Classic Hodgkin Lymphoma

scientific article

Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma

scientific article

Phase II study of pembrolizumab (MK-3475) for relapsed/refractory classical Hodgkin Lymphoma (r/r cHL): keynote-087.

scientific article published on 4 November 2015

Programmed Death-1 Blockade With Pembrolizumab in Patients With Classical Hodgkin Lymphoma After Brentuximab Vedotin Failure

scientific article published on 27 June 2016

Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation

scientific article

Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

Reply to Z. Wu et al

scientific article published on 30 May 2018

Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group

scientific article

Report of the first workshop on prognostic factors in large-cell lymphomas

scientific article published in February 1991

Report on a workshop convened to discuss the pathological and staging classifications of gastrointestinal tract lymphoma

scientific article

Rituximab and CHOP induction therapy for newly diagnosed mantle-cell lymphoma: molecular complete responses are not predictive of progression-free survival

scientific article published in March 2002

SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas

scientific article published on June 2013

SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

scientific article

Safety and tolerability of pembrolizumab in patients with relapsed/refractory primary mediastinal large B-cell lymphoma.

scientific article published on 10 May 2017

Selective JAK2 inhibition specifically decreases Hodgkin lymphoma and mediastinal large B-cell lymphoma growth in vitro and in vivo

scientific article published on 7 March 2014

Seventy-two hour continuous infusion flavopiridol in relapsed and refractory mantle cell lymphoma

scientific article published in April 2002

Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma

scientific article published on 22 November 2017

Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma.

scientific article published in December 2017

Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

scientific article

Spatial Signatures Identify Immune Escape via PD-1 as a Defining Feature of T-cell/Histiocyte-rich Large B-cell Lymphoma

scientific article published on 01 September 2020

TRAF1 expression and c-Rel activation are useful adjuncts in distinguishing classical Hodgkin lymphoma from a subset of morphologically or immunophenotypically similar lymphomas

scientific article published on 01 February 2005

Targetable genetic features of primary testicular and primary central nervous system lymphomas

scientific article published on 23 December 2015

Targeted inhibition of PI3Kα/δ is synergistic with BCL-2 blockade in genetically defined subtypes of DLBCL

scientific article published on 15 October 2018

The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphoma

scholarly article

The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity

scientific article (publication date: 13 June 2003)

The BRAF Pseudogene Is a Proto-Oncogenic Competitive Endogenous RNA ⬇️

scholarly article

The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.

scientific article

The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on April 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on 11 July 2016

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia

scientific article published on 20 December 2016

The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27).

scientific article

The heat shock protein 90 inhibitor IPI-504 induces apoptosis of AKT-dependent diffuse large B-cell lymphomas.

scientific article

The microenvironmental niche in classic Hodgkin lymphoma is enriched for CTLA-4-positive T cells that are PD-1-negative

scientific article published on 01 December 2019

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

scientific article

The phosphodiesterase PDE4B limits cAMP-associated PI3K/AKT-dependent apoptosis in diffuse large B-cell lymphoma

scientific article

The pre-B-cell receptor associated protein VpreB3 is a useful diagnostic marker for identifying c-MYC translocated lymphomas

scientific article

Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma.

scientific article published on 11 September 2017

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

scholarly article

Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders

scientific article published on 7 February 2011

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