List of works - Xianming Deng

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2.

scientific article published on 6 March 2011

Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein

scientific article published on September 14, 2010

GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor

scientific article

Brain Penetrant LRRK2 Inhibitor

scientific article

High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors

scientific article

Characterization of TAE684 as a potent LRRK2 kinase inhibitor

scientific article

Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

scientific article published on January 2014

Leucine-rich repeat kinase 2 inhibitors: a patent review (2006 – 2011)

scientific article published on November 6, 2012

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

scientific article published on 29 October 2013

Expanding the Diversity of Allosteric Bcr-Abl Inhibitors

scientific article published on October 14, 2010

Small-Molecule Inhibitors of the c-Fes Protein-Tyrosine Kinase

scientific article

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

scientific article

Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase

scientific article published on June 5, 2015

Aspertetranones A–D, Putative Meroterpenoids from the Marine Algal-Associated Fungus Aspergillus sp. ZL0-1b14

scientific article published on September 17, 2015

Discovery of 3,5-Diamino-1,2,4-triazole Ureas as Potent Anaplastic Lymphoma Kinase Inhibitors

scientific article published on March 15, 2011

Two new spirooxindole alkaloids from rhizosphere strain Streptomyces sp. xzqh-9

scientific article published on September 16, 2014

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

scientific article published on 31 August 2018

Heat shock protein 90 inhibitor mycoepoxydiene modulates kinase signaling in cervical cancer cells and inhibits in-vivo tumor growth

scientific article published on January 1, 2015

An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kit

scientific article published on June 6, 2012

Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities

scientific article published on 19 June 2018

Kribbella mirabilis sp. nov., isolated from rhizosphere soil of a herbaceous plant, Mirabilis jalapa L

scientific article published on June 25, 2015

A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant BtkC481S mutation in B-cell malignancies

scientific article published on 09 December 2019

Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

scientific article published on 23 August 2018

Kibdelosporangium lantanae sp. nov., isolated from the rhizosphere soil of an ornamental plant, Lantana camara L

scientific article published on May 7, 2015

Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis

scientific article published on 15 May 2020

Low-dose metformin targets the lysosomal AMPK pathway through PEN2

scientific article published on 23 February 2022

Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility

scientific article published on 27 May 2020

A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC

scientific article published on 30 November 2021

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression

scientific article published on 21 October 2020

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"

scientific article published on 13 August 2020

List of works by Xianming Deng

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2.

Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein

GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor

Brain Penetrant LRRK2 Inhibitor

High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors

Characterization of TAE684 as a potent LRRK2 kinase inhibitor

Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

Leucine-rich repeat kinase 2 inhibitors: a patent review (2006 – 2011)

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Expanding the Diversity of Allosteric Bcr-Abl Inhibitors

Small-Molecule Inhibitors of the c-Fes Protein-Tyrosine Kinase

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase

Aspertetranones A–D, Putative Meroterpenoids from the Marine Algal-Associated Fungus Aspergillus sp. ZL0-1b14

Discovery of 3,5-Diamino-1,2,4-triazole Ureas as Potent Anaplastic Lymphoma Kinase Inhibitors

Two new spirooxindole alkaloids from rhizosphere strain Streptomyces sp. xzqh-9

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

Heat shock protein 90 inhibitor mycoepoxydiene modulates kinase signaling in cervical cancer cells and inhibits in-vivo tumor growth

An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kit

Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities

Kribbella mirabilis sp. nov., isolated from rhizosphere soil of a herbaceous plant, Mirabilis jalapa L

A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant BtkC481S mutation in B-cell malignancies

Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

Kibdelosporangium lantanae sp. nov., isolated from the rhizosphere soil of an ornamental plant, Lantana camara L

Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis

Low-dose metformin targets the lysosomal AMPK pathway through PEN2

Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility

A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"