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List of works by Julia E Rager

17β-estradiol and tamoxifen prevent gastric cancer by modulating leukocyte recruitment and oncogenic pathways in Helicobacter pylori-infected INS-GAS male mice

scientific article

A Framework for Systematic Evaluation and Quantitative Integration of Mechanistic Data in Assessments of Potential Human Carcinogens

scientific article published on 01 February 2019

A high dose mode of action for tetrabromobisphenol A-induced uterine adenocarcinomas in Wistar Han rats: A critical evaluation of key events in an adverse outcome pathway framework

scientific article published on 28 January 2016

A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid

scientific article published on 18 September 2018

A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates

scientific article published on 21 April 2018

A role for microRNAs in the epigenetic control of sexually dimorphic gene expression in the human placenta

scientific article published on 09 September 2020

A toxicogenomic comparison of primary and photochemically altered air pollutant mixtures

scientific article published on 14 July 2011

Air toxics and epigenetic effects: ozone altered microRNAs in the sputum of human subjects

scientific article

Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile.

scientific article published on January 2012

Arsenic and the epigenome: interindividual differences in arsenic metabolism related to distinct patterns of DNA methylation

scientific article published on 11 January 2013

Bayesian matrix completion for hypothesis testing

scientific article published in 2023

Benchmark Dose Modeling Estimates of the Concentrations of Inorganic Arsenic That Induce Changes to the Neonatal Transcriptome, Proteome, and Epigenome in a Pregnancy Cohort.

scientific article

Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs.

scientific article published on 28 October 2013

Comparative genomic analyses identify common molecular pathways modulated upon exposure to low doses of arsenic and cadmium

scientific article

Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway

scientific article published on 26 September 2019

Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium.

scientific article published on 6 March 2016

DNA methylation in nasal epithelial cells from smokers: identification of ULBP3-related effects

scientific article published on 05 July 2013

Developing novel in vitro methods for the risk assessment of developmental and placental toxicants in the environment

scientific article published on 22 June 2019

Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research

scientific article published in 2022

Epigenetic changes in individuals with arsenicosis

scientific article

Epigenetic changes induced by air toxics: formaldehyde exposure alters miRNA expression profiles in human lung cells

scientific article

Formaldehyde and epigenetic alterations: microRNA changes in the nasal epithelium of nonhuman primates.

scientific article published on 15 January 2013

Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment

scientific article

Formaldehyde-associated changes in microRNAs: tissue and temporal specificity in the rat nose, white blood cells, and bone marrow

scientific article published on 04 December 2013

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure

scientific article

Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer

scientific article published on 3 June 2015

Identifying Attributes That Influence In Vitro-to-In Vivo Concordance by Comparing In Vitro Tox21 Bioactivity Versus In Vivo DrugMatrix Transcriptomic Responses Across 130 Chemicals.

scientific article published in January 2019

Identifying the Transcriptional Response of Cancer and Inflammation-Related Genes in Lung Cells in Relation to Ambient Air Chemical Mixtures in Houston, Texas

scientific article published on 16 October 2020

Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways

scientific article published on 3 October 2012

Influenza enhances caspase-1 in bronchial epithelial cells from asthmatic volunteers and is associated with pathogenesis.

scientific article

Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA.

scientific article published on 29 December 2017

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium.

scientific article published on 24 October 2017

Integrative exposomic, transcriptomic, epigenomic analyses of human placental samples links understudied chemicals to preeclampsia

scientific article published in 2022

Linking Coregulated Gene Modules with Polycyclic Aromatic Hydrocarbon-Related Cancer Risk in the 3D Human Bronchial Epithelium

scientific article published on 28 May 2021

Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring

scientific article

Metabolomic characteristics of arsenic-associated diabetes in a prospective cohort in Chihuahua, Mexico

scientific article

Mixtures modeling identifies chemical inducers versus repressors of toxicity associated with wildfire smoke

scientific article published in 2021

New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing

scientific article published on 23 March 2020

Placental Genomic and Epigenomic Signatures Associated with Infant Birth Weight Highlight Mechanisms Involved in Collagen and Growth Factor Signaling

scientific article published on 25 July 2020

Prenatal arsenic exposure and shifts in the newborn proteome: interindividual differences in tumor necrosis factor (TNF)-responsive signaling

scientific article

Prenatal arsenic exposure and the epigenome: altered microRNAs associated with innate and adaptive immune signaling in newborn cord blood.

scientific article

Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes

scientific article

Prenatal exposure to arsenic and cadmium impacts infectious disease-related genes within the glucocorticoid receptor signal transduction pathway

journal article published in 2014

Review of the environmental prenatal exposome and its relationship to maternal and fetal health

scientific article published on 22 February 2020

Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis

scientific article published on 25 January 2019

Strengthening Causal Inference in Exposomics Research: Application of Genetic Data and Methods

scientific article published in 2022

Systems biology and birth defects prevention: blockade of the glucocorticoid receptor prevents arsenic-induced birth defects

scientific article published on 3 January 2013

T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX.

scientific article published on 28 September 2015

The aryl hydrocarbon receptor pathway: a key component of the microRNA-mediated AML signalisome

scientific article

The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic

scientific article

The placenta epigenome-brain axis: placental epigenomic and transcriptomic responses that preprogram cognitive impairment

journal article published in 2022

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.

scientific article

Two distinct trophectoderm lineage stem cells from human pluripotent stem cells

scientific article published on 01 January 2021

Use of Genome Editing Tools in Environmental Health Research

scientific article published on 02 March 2019

Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings through Transcriptomic Similarity Scoring

scientific article published in 2022

Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke

scientific article published in 2022

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