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List of works by Yoshihisa Yamano

A case of post-transplant adult T-cell leukemia/lymphoma presenting myelopathy similar to but distinct from human T-cell leukemia virus type I (HTLV- I)-associated myelopathy

scientific article

A plasma diagnostic model of human T-cell leukemia virus-1 associated myelopathy

scientific article published on 16 January 2015

A three-factor plasma diagnostic model of human T -cell leukemia virus-1 associated myelopathy.

scientific article

Abnormally high levels of virus-infected IFN-gamma+ CCR4+ CD4+ CD25+ T cells in a retrovirus-associated neuroinflammatory disorder

scientific article

Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha

scientific article published on January 2009

Advantage of higher-avidity CTL specific for Tax against human T-lymphotropic virus-1 infected cells and tumors ⬇️

scientific article published on October 8, 2011

An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-protein

scientific journal article

CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis

scientific article (publication date: 2013)

CXCL10 and neopterin in CSF are candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis.

scientific article published on 7 January 2014

Characteristics of HAM/TSP after kidney transplantation from HTLV-1 positive living donors.

scientific article published on 28 August 2015

Clinical Pathophysiology of Human T-Lymphotropic Virus-Type 1-Associated Myelopathy/Tropical Spastic Paraparesis ⬇️

scientific article published on November 9, 2012

Clinical subtype of HAM/TSP based on clinical course and laboratory findings

scientific article published on 6 June 2011

Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8+ T cells, and disease severity in HTLV-1–associated myelopathy (HAM/TSP) ⬇️

scientific article published on January 1, 2002

Creation and validation of a bladder dysfunction symptom score for HTLV-1-associated myelopathy/tropical spastic paraparesis

scientific article published on 03 July 2020

Detection of virus-specific T cells and CD8+ T-cell epitopes by acquisition of peptide-HLA-GFP complexes: analysis of T-cell phenotype and function in chronic viral infections

scientific article published on 24 March 2003

Developing novel treatments for HTLV-1-associated myelopathy (HAM) by investigating molecular pathomechanisms

scientific article published on January 2016

Direct phenotypic analysis of human MHC class I antigen presentation: visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human recombinant antibodies

scientific article

Dysregulation of TGF-beta signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease

scientific article published on 7 March 2008

E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis ⬇️

scientific article (publication date: 25 October 2010)

Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study

scientific article published on 23 May 2017

Evaluation of clinical outcome measures for HAM/TSP.

scientific article

Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type-1-associated neurological disease

scientific article published on January 2011

Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers ⬇️

scientific article published on December 7, 2011

HAM-net national patient registration system reveals details of how Japanese patients with HTLV-1-associated myelopathy/tropical spastic paraparesis progress over time

scientific article published on 28 August 2015

HTLV-1 Tax induces Th1 master regulator T-bet and thus IFN-γ in CD4+CCR4+ T-cells of virus-associated myelopathy patients.

scientific article published on 28 August 2015

HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

scientific article

HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells that produces an inflammatory positive feedback loop via astrocytes in HAM/TSP.

scientific article published on 12 August 2016

HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors

scientific article published on 3 December 2015

HTLV-1-associated myelopathy(HAM)

scientific article published on September 2015

Human T-Lymphotropic Virus Type 1 (HTLV-1) and Regulatory T Cells in HTLV-1-Associated Neuroinflammatory Disease ⬇️

scientific article published on August 25, 2011

Humanized anti CCR4 antibody KW0761 targets HTLV-1 infected CD4+ CCR4+ and CD8+CCR4+ T cells to treat HAM/TSP.

scientific article published on 28 August 2015

IL-10-mediated signals act as a switch for lymphoproliferation in Human T-cell leukemia virus type-1 infection by activating the STAT3 and IRF4 pathways.

scientific article published on 14 September 2017

Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis

scientific article published on 9 February 2012

Increased expression of human T lymphocyte virus type I (HTLV-I) Tax11-19 peptide-human histocompatibility leukocyte antigen A*201 complexes on CD4+ CD25+ T Cells detected by peptide-specific, major histocompatibility complex-restricted antibodies i

scientific article

Increased prevalence of group A β-hemolytic streptococcus among an ethnic population in Kyrgyzstan detected by the rapid antigen detection test ⬇️

scientific article published on November 1, 2008

Inhibitory effects of ubiquitination of synoviolin by PADI4.

scientific article published on 11 October 2017

Interferon-beta1a therapy in human T-lymphotropic virus type I-associated neurologic disease

scientific article

Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy

scientific article published in February 2018

Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy

scientific article published on 7 August 2014

Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis

scientific article published on 11 May 2020

Nation-wide epidemiological study in Japan on HTLV-1 associated myelopathy/tropical spastic paraparesis using HAM-net, a novel patient registration system

scientific article published on 7 January 2014

Nation-wide epidemiological study of Japanese patients with rare viral myelopathy using novel registration system (HAM-net).

scientific article published on 25 May 2016

Neuroimmunity of HTLV-I Infection

scientific article published on 02 May 2010

Overexpression of SPACIA1/SAAL1, a newly identified gene that is involved in synoviocyte proliferation, accelerates the progression of synovitis in mice and humans ⬇️

scientific article published on December 1, 2011

Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy

scientific article published on 26 July 2013

Possibility of γδ T cell immunotherapy for HTLV-1-infected individuals

scientific article published on 6 June 2011

Potential Contribution of a Novel Tax Epitope–Specific CD4+ T Cells to Graft-versus-Tax Effect in Adult T Cell Leukemia Patients after Allogeneic Hematopoietic Stem Cell Transplantation ⬇️

scientific article published on March 8, 2013

Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia ⬇️

scientific article published on March 28, 2013

Prevalence of Group A b-Hemolytic Streptococcus Among Children with Tonsillopharyngitis in Kyrgyzstan: The Difficulty of Diagnostics and Therapy ⬇️

scientific article published on October 13, 2010

Proposal of Classification Criteria for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Disease Activity

scientific article published in 2018

Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes ⬇️

scientific article published on September 24, 2010

Proteomic profiling of HTLV-1 infected T-cells for the identification of potential biomarkers and therapeutic targets for HTLV-1 associated myelopathy/ tropical spastic paraparesis and adult T-cell leukemia

scientific article published on 6 June 2011

Proviral Features of Human T Cell Leukemia Virus Type 1 in Carriers with Indeterminate Western Blot Analysis Results.

scientific article published on 12 July 2017

Quantitative Computed Tomography Measurement of Tracheal Cross-Sectional Areas in Relapsing Polychondritis: Correlations with Spirometric Values

scientific article

RAISING is a high-performance method for identifying random transgene integration sites

scientific article published on 02 June 2022

RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis ⬇️

scientific article published on September 18, 2012

Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan

scientific article published on 21 October 2019

Reducing the global burden of HTLV-1 infection: An agenda for research and action

scientific article

Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase.

scientific article published on November 2009

SPACIA1/SAAL1: a newly identified gene associated with aberrant proliferation of synovial fibroblasts

article

Severe loss of invariant NKT cells exhibiting anti-HTLV-1 activity in patients with HTLV-1-associated disorders.

scientific article published on 07 August 2009

Standardization of Quantitative PCR for Human T-Cell Leukemia Virus Type 1 in Japan: a Collaborative Study.

scientific article

The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β

scientific article published on 19 February 2015

The Impact of a Humanized CCR4 Antibody (Mogamulizumab) on Patients with Aggressive-Type Adult T-Cell Leukemia-Lymphoma Treated with Allogeneic Hematopoietic Stem Cell Transplantation.

scientific article published on January 2017

The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale: reliability and validity ⬇️

scientific article published on May 10, 2011

The Japanese version of the modified ACR preliminary diagnostic criteria for fibromyalgia and the fibromyalgia symptom scale: reliability and validity

scientific article

The contribution of Asian researchers to the field of rheumatology

scientific article published on February 2010

The current and future approaches to the treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

scientific article published on April 1, 2012

The plasticity of HTLV-1 infected CD4+CD25+CCR4+ T-cells through HTLV-1 tax in HAM/TSP.

scientific article

Timed walk as primary outcome measure of treatment response in clinical trials for HTLV-1-associated myelopathy: a feasibility study

scientific article published on 23 October 2015

Treatment of rheumatoid arthritis with biologics may exacerbate HTLV-1-associated conditions: A case report

scientific article published on February 2017

Usefulness of proviral load measurement for monitoring of disease activity in individual patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis

scientific article published on February 2003

Utility of HTLV proviral load quantification in diagnosis of HTLV-1-associated myelopathy requires international standardization.

scientific article published on 13 September 2013

Virus-induced CXCL10-CXCR3 positive feedback loop via astrocytes is critical for maintaining chronic inflammatory lesions in HAM/TSP.

scientific article published on 7 January 2014

Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease

scientific article

Vulnerability to traumatic stress in fibromyalgia patients: 19 month follow-up after the great East Japan disaster

scientific article published on 23 September 2013

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