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List of works by Steven A Lubitz

2020 APHRS/HRS Expert Consensus Statement on the Investigation of Decedents with Sudden Unexplained Death and Patients with Sudden Cardiac Arrest, and of Their Families

scientific article published on 13 October 2020

50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study

scientific article

A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a

scientific article published on 16 November 2016

A Genetic Risk Score for Atrial Fibrillation Predicts the Response to Catheter Ablation

scientific article published on 17 December 2018

A Simple and Portable Algorithm for Identifying Atrial Fibrillation in the Electronic Medical Record

scientific article

A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation

scientific article

A common connexion between gap junctions, single nucleotide polymorphisms, and atrial fibrillation?

scientific article

A comparison of the CHARGE-AF and the CHA2DS2-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study

scientific article published on 17 May 2016

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A polygenic risk score predicts atrial fibrillation in cardiovascular disease

scientific article published in 2022

Accuracy and Usability of a Novel Algorithm for Detection of Irregular Pulse Using a Smartwatch Among Older Adults: Observational Study

scientific article published on 15 May 2019

Actionable exomic incidental findings in 6503 participants: challenges of variant classification

scientific article

Age of natural menopause and atrial fibrillation: the Framingham Heart Study

scientific article published on 29 March 2012

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

scientific article published on 07 May 2020

Aspirin Instead of Oral Anticoagulant Prescription in Atrial Fibrillation Patients at Risk for Stroke

scientific article published on June 2016

Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study

article published in 2019

Association Between Frailty and Atrial Fibrillation in Older Adults: The Framingham Heart Study Offspring Cohort

scientific article published on 29 December 2020

Association Between Leukocyte Telomere Length and the Risk of Incident Atrial Fibrillation: The Framingham Heart Study

scientific article published on 14 November 2017

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Association between familial atrial fibrillation and risk of new-onset atrial fibrillation

scientific article

Association of insurance type with receipt of oral anticoagulation in insured patients with atrial fibrillation: A report from the American College of Cardiology NCDR PINNACLE registry.

scientific article published on 31 August 2017

Associations Between Alcohol Intake and Genetic Predisposition with Atrial Fibrillation Risk in a National Biobank

scientific article published on 06 November 2020

Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation

scientific article published on 17 March 2016

Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction

scientific article published on 8 January 2016

Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms

scientific article published on 3 May 2017

Atrial Fibrillation Genetics: Is There a Practical Clinical Value Now or in the Future?

scientific article published on 12 February 2016

Atrial Fibrillation Risk and Discrimination of Cardioembolic From Noncardioembolic Stroke

scientific article published on 07 April 2020

Atrial fibrillation and death after myocardial infarction: risk marker or causal mediator?

scientific article published on 2 May 2011

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

Atrial fibrillation in congestive heart failure

scientific article

Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community

scientific article published on 03 September 2013

Atrial fibrillation: current knowledge and future directions in epidemiology and genomics

scientific article published on November 2011

Atrial flutter: Clinical risk factors and adverse outcomes in the Framingham Heart Study

scientific article

Automated Electronic Phenotyping of Cardioembolic Stroke

scientific article published on 10 December 2020

B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies

scientific article published on 18 July 2014

Biventricular pacing: more is better!

scientific article published on 8 October 2014

Blood lipids and the incidence of atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis and the Framingham Heart Study

scientific article

CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing

scientific article

Catheter ablation for atrial fibrillation

scientific article published in the British Medical Journal

Challenges in the classification of atrial fibrillation

scientific article

Changes in Use of Anticoagulation in Patients With Atrial Fibrillation Within a Primary Care Network Associated With the Introduction of Direct Oral Anticoagulants

scientific article published on 15 June 2017

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease

scientific article published on 13 November 2020

Clinical and genetic evaluation after sudden cardiac arrest

scientific article published on 15 January 2020

Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction

scientific article published on 01 May 2018

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common genetic variants and response to atrial fibrillation ablation

scientific article published on 14 February 2015

Common variants in KCNN3 are associated with lone atrial fibrillation

scientific article

Copy Number Variation and Warfarin Dosing: Evaluation of CYP2C9 , VKORC1 , CYP4F2 , GGCX and CALU ⬇️

scientific article published on December 21, 2011

Deep learning enables genetic analysis of the human thoracic aorta

scientific article published on 26 November 2021

Design and rationale of a pragmatic trial integrating routine screening for atrial fibrillation at primary care visits: The VITAL-AF trial

scientific article published on 22 June 2019

Development and Validation of a Prediction Model for Atrial Fibrillation Using Electronic Health Records

scientific article published on 02 October 2019

Development of a clinical polygenic risk score assay and reporting workflow

scientific article published on 18 April 2022

Dietary factors and incident atrial fibrillation: the Framingham Heart Study

scientific article

Diminished PRRX1 Expression Is Associated With Increased Risk of Atrial Fibrillation and Shortening of the Cardiac Action Potential

scientific article

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals

scientific article published on 17 February 2019

Effect of a Multidisciplinary Approach for the Management of Patients With Atrial Fibrillation in the Emergency Department on Hospital Admission Rate and Length of Stay

scientific article

Effectiveness of cardiac resynchronization therapy in mild congestive heart failure: systematic review and meta-analysis of randomized trials

scientific article

Electronic physician notifications to improve guideline-based anticoagulation in atrial fibrillation: a randomized controlled trial

scientific article published on 03 August 2018

Elevation of parathyroid hormone levels in atrial fibrillation.

scientific article published on June 2011

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

scientific article published on 7 September 2020

Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation

scientific article published on 06 November 2020

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article published on 2 August 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

scientific article published in July 2017

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: What is the best practice?

scientific article published on 23 March 2018

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: what is the best practice?

scientific article published on 01 September 2018

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: what is the best practice?

scientific article published on 18 March 2018

European ancestry as a risk factor for atrial fibrillation in African Americans

scientific article

Evaluation of non-synonymous NPPA single nucleotide polymorphisms in atrial fibrillation

scientific article

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Factors Associated with Anticoagulation Delay Following New-Onset Atrial Fibrillation.

scientific article

Fifteen Genetic Loci Associated With the Electrocardiographic P Wave

scientific article

Frequency of Cardiac Rhythm Abnormalities in a Half Million Adults

scientific article published on 01 July 2018

Galectin 3 and incident atrial fibrillation in the community

scientific article

Gene-gene Interaction Analyses for Atrial Fibrillation

scientific article

Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

scientific article published on 21 August 2020

Genetic Factors Influencing Warfarin Dose in Black-African Patients: A Systematic Review and Meta-Analysis

scientific article published on 23 December 2019

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

scientific article published on 12 September 2017

Genetic Link Between Arterial Stiffness and Atrial Fibrillation

scientific article published on 18 June 2019

Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization

scientific article published on 14 December 2016

Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation.

scientific article published on 12 November 2017

Genetic Risk Prediction of Atrial Fibrillation

scientific article published on 28 October 2016

Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation

scientific article published on 14 February 2020

Genetic etiology and evaluation of sudden cardiac death

scientific article published on August 2013

Genetic loci associated with atrial fibrillation: relation to left atrial structure in the Framingham Heart Study

scientific article

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article

Genetic susceptibility to atrial fibrillation: does heart failure change our perspective?

scientific article published on 12 January 2013

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

scientific article published on 05 June 2013

Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy.

scientific article

Genetically Determined Birthweight Associates with Atrial Fibrillation: A Mendelian Randomization Study

scientific article published on 27 April 2020

Genetics of Atrial Fibrillation: State of the Art in 2017.

scientific article

Genetics of atrial fibrillation

scientific article published on 01 April 2010

Genetics of atrial fibrillation: implications for future research directions and personalized medicine

scientific article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association studies in cardiac electrophysiology: recent discoveries and implications for clinical practice

scientific article

Genome-wide association studies of the PR interval in African Americans

scientific article

Genome-wide association study of PR interval

scientific article

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

article by Amit V Khera et al published September 2018 in Nature Genetics

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

scientific article published on 16 October 2020

Genomic risk scores in atrial fibrillation: predicting the unpredictable?: Figure 1 ⬇️

scientific article published on April 12, 2013

Heritability of Atrial Fibrillation

scientific article published in December 2017

Impact of a Multidisciplinary Treatment Pathway for Atrial Fibrillation in the Emergency Department on Hospital Admissions and Length of Stay: Results of a Multi-Center Study

scientific article published on 12 September 2019

Increased perforation risk with an MRI-conditional pacing lead: a single-center study.

scientific article

Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

scientific article

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Initial Precipitants and Recurrence of Atrial Fibrillation

scientific article published on 12 February 2020

Insulin resistance and atrial fibrillation (from the Framingham Heart Study)

scientific article published on 12 October 2011

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

scientific article published on 14 August 2014

Integrative Omics Approach to Identifying Genes Associated With Atrial Fibrillation

scientific article published on 05 December 2019

Korean Atrial Fibrillation (AF) Network: Genetic Variants for AF Do Not Predict Ablation Success

scientific article

Lack of replication in polymorphisms reported to be associated with atrial fibrillation

scientific article

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project

scientific article published on 16 August 2011

Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study.

scientific article

Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease

scientific article published on 01 June 2020

Long-term outcomes of secondary atrial fibrillation in the community: the Framingham Heart Study

scientific article published on 13 March 2015

Low serum magnesium and the development of atrial fibrillation in the community: the Framingham Heart Study

scientific article published on 21 November 2012

Massachusetts general hospital Covid-19 registry reveals two distinct populations of hospitalized patients by race and ethnicity

scientific article published on 22 December 2020

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

scientific article published on 29 April 2012

Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study).

scientific article published on 24 August 2016

Methylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study

scientific article

Monogenic and Polygenic Contributions to Atrial Fibrillation Risk: Results From a National Biobank

scientific article published on 06 November 2019

Monogenic atrial fibrillation as pathophysiological paradigms

scientific article

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

New-onset atrial fibrillation during hospitalization

scientific article published on December 2014

Next-generation sequencing for the diagnosis of cardiac arrhythmia syndromes

scientific article published on 24 January 2015

Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy

scientific article published in December 2017

Novel Risk Modeling Approach of Atrial Fibrillation With Restricted Mean Survival Times: Application in the Framingham Heart Study Community-Based Cohort

scientific article published on 31 March 2020

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

scientific article published on 30 January 2014

Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts

scientific article

Oral Anticoagulant Therapy Prescription in Patients With Atrial Fibrillation Across the Spectrum of Stroke Risk: Insights From the NCDR PINNACLE Registry

scientific article published on April 2016

P wave duration and risk of longitudinal atrial fibrillation in persons ≥ 60 years old (from the Framingham Heart Study)

scientific article

P-wave indices: derivation of reference values from the Framingham Heart Study

scientific article

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

scientific article published in Nature Communications

Performance of Atrial Fibrillation Risk Prediction Models in Over Four Million Individuals

scientific article published on 09 December 2020

Personalized medicine and atrial fibrillation: will it ever happen?

scientific article

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

scientific article published on 11 November 2018

Plasma resistin, adiponectin, and risk of incident atrial fibrillation: the Framingham Offspring Study

scientific article

Population-Based Screening for Atrial Fibrillation

scientific article published on 18 June 2020

Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial

scientific article published on 11 November 2019

Predictive Accuracy of a Clinical and Genetic Risk Model for Atrial Fibrillation

scientific article

Predictors of oral anticoagulant non-prescription in patients with atrial fibrillation and elevated stroke risk

scientific article published on 10 March 2018

Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis

scientific article published on 21 January 2016

Protein Biomarkers and Risk of Atrial Fibrillation: The FHS

scientific article published on 15 January 2020

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Proteomics Profiling and Risk of New‐Onset Atrial Fibrillation: Framingham Heart Study

scientific article published on 01 March 2019

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rationale and design of a large population study to validate software for the assessment of atrial fibrillation from data acquired by a consumer tracker or smartwatch: The Fitbit heart study

scientific article published on 16 April 2021

Recent Trends in Oral Anticoagulant Use and Post-Discharge Complications Among Atrial Fibrillation Patients with Acute Myocardial Infarction.

scientific article published on 28 February 2018

Reciprocal relations between physical disability, subjective health, and atrial fibrillation: the Framingham Heart Study

scientific article published on 30 April 2013

Reduced appropriate implantable cardioverter-defibrillator therapy after cardiac resynchronization therapy-induced left ventricular function recovery: a meta-analysis and systematic review

scientific article

Refining the Association Between Body Mass Index and Atrial Fibrillation: G-Formula and Restricted Mean Survival Times

scientific article published on 08 August 2019

Relation of Orthostatic Hypotension With New-Onset Atrial Fibrillation (From the Framingham Heart Study).

scientific article published on 11 December 2017

Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study

scientific article published on 19 August 2020

Relations of Arterial Stiffness and Brachial Flow-Mediated Dilation With New-Onset Atrial Fibrillation: The Framingham Heart Study

scientific article published on 25 July 2016

Relations of Liver Fat With Prevalent and Incident Atrial Fibrillation in the Framingham Heart Study

scientific article published on 2 May 2017

Response by Aragam et al to Letter Regarding Article, "Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery"

scientific article published on 01 July 2019

Response by Lubitz et al to Letter Regarding Article, "Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study".

scientific article published on 17 April 2017

Response to Letter Regarding Article, "Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction"

scientific article published on June 2016

Response to Letter Regarding Article, “Symptoms and Functional Status of Patients With Atrial Fibrillation: State of the Art and Future Research Opportunities”

Risk assessment for incident heart failure in individuals with atrial fibrillation

scientific article

Risk of Stroke in Patients With Atrial Fibrillation Is Associated With Stroke in Siblings: A Nationwide Study

scientific article published on 03 February 2020

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

scientific article

Serum brain-derived neurotrophic factor and risk of atrial fibrillation.

scientific article

Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium

scientific article published on 18 March 2013

Somatic mutations and atrial fibrillation: the end or just the beginning?

scientific article published on February 2015

Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study

scientific article published on 12 January 2017

Stroke prevention in atrial fibrillation in older adults: existing knowledge gaps and areas for innovation: a summary of an American Federation for Aging research seminar

scientific article published on 19 September 2013

Stroke risk in AF: do AF patterns matter?

scientific article

Structural Abnormalities on Cardiac Magnetic Resonance Imaging in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

scientific article published on 01 June 2020

Symptoms and functional status of patients with atrial fibrillation: state of the art and future research opportunities

scientific article

Systemic Embolic Events (SEE) in Atrial Fibrillation: SEEing Embolic Risk More Clearly

scientific article

Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

scientific article (publication date: March 2014)

The Effect of PCSK9 Inhibition on the Risk of Venous Thromboembolism

scientific article published on 29 March 2020

Titin Truncating Variants in Adults Without Known Congestive Heart Failure

scientific article published on 01 March 2020

Trajectories of Risk Factors and Risk of New-Onset Atrial Fibrillation in the Framingham Heart Study

scientific article

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

scientific article published on 20 May 2020

Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke

scientific article

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article published on 23 December 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article

Validation of Polygenic Scores for QT Interval in Clinical Populations

scientific article published in October 2017

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry ⬇️

scientific article published on 13 July 2009

Vitamin D status is not related to development of atrial fibrillation in the community

scientific article

Warfarin pharmacogenetic trials: is there a future for pharmacogenetic-guided dosing?

scientific article

Warfarin pharmacogenetics: a controlled dose-response study in healthy subjects

scientific article published on 12 September 2013

Wearing Your Heart on Your Sleeve: the Future of Cardiac Rhythm Monitoring

scientific article published on 25 November 2019

White blood cell count and risk of incident atrial fibrillation (from the Framingham Heart Study)

scientific article published on 17 November 2011

Whole Exome Sequencing in Atrial Fibrillation

scientific article

Whole blood gene expression and atrial fibrillation: the Framingham Heart Study

scientific article

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