List of works - Emma Gostick

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

scientific article published on 18 September 2007

A human memory T cell subset with stem cell-like properties

scientific article

A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells

scientific article

AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape

scientific article

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation, function and EBV immunity.

scientific article

Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus

scientific article published on 19 June 2013

Allogeneic HLA-A*02-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuity

scientific article published on 05 August 2011

Analysis of the functional WT1-specific T-cell repertoire in healthy donors reveals a discrepancy between CD4(+) and CD8(+) memory formation

scientific article published on 19 June 2015

Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers

scientific article published on July 2006

Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling

scientific article

Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective antileukemia reactivity

scientific article

Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope

scientific article published on June 2007

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses

scientific article

Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells

scientific article

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

scientific article

CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation

scientific article published on 14 November 2007

CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold

scientific article published on 27 September 2016

CMV driven CD8(+) T-cell activation is associated with acute rejection in lung transplantation.

scientific article published on 29 March 2013

Cellular-level versus receptor-level response threshold hierarchies in T-cell activation

scientific article published on 05 September 2013

Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency

scientific article published on 23 December 2016

Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization

scientific article published on 6 February 2013

Conditional CD8+ T cell escape during acute simian immunodeficiency virus infection

scientific article published on 19 October 2011

Critical role of TLR7 signaling in the priming of cross-protective cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine

scientific article

Crystallization and preliminary X-ray structural studies of a Melan-A pMHC-TCR complex

scientific article

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses.

scientific article published on 21 April 2017

Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells.

scientific article

Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

scientific article published on 22 August 2017

Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.

scientific article

Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers

scientific article published on 31 July 2008

Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

scientific article published in Journal of Biological Chemistry

Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions

scientific article published on 7 February 2018

ERAP1 allotypes shape the epitope repertoire of virus-specific CD8+ T cell responses in acute hepatitis C virus infection.

scientific article published on 13 February 2019

Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers

scientific article

Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells

scientific article published on 01 December 2019

Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy

scientific article

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

scientific article published on May 2007

Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations

scientific article

Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

scientific article published on July 2015

Escape from highly effective public CD8+ T-cell clonotypes by HIV

scientific article published on 6 July 2011

Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer

scientific article published on 15 July 2015

Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency

scientific article published on 30 June 2020

Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239{Delta}nef-vaccinated macaques suppress SIVmac239 replication ex vivo

scientific article published on 20 January 2010

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

scientific article

Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor

scientific article

Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.

scientific article published on 26 June 2003

GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo

scientific article published in 2011

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

scientific article

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

scientific article

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response

scientific article published on 25 September 2017

Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia

scientific article

HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue

scientific article published in December 2017

Heterosubtypic cross-protection induced by whole inactivated influenza virus vaccine in mice: influence of the route of vaccine administration

scientific article

High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow

scientific article

High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance

scientific article published on 03 July 2013

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

scientific article

Holoendemic malaria exposure is associated with altered Epstein-Barr virus-specific CD8(+) T-cell differentiation

scientific article published on 21 November 2012

Human TCR-binding affinity is governed by MHC class restriction

scientific article

IL-10 restricts memory T cell inflation during cytomegalovirus infection

scientific article published on 16 August 2010

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine ⬇️

scientific article published on 01 February 2019

Identification and In Vitro Expansion of Functional Antigen-Specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection

scientific article (publication date: May 2008)

Identification and characterization of HIV-specific resident memory CD8 + T cells in human lymphoid tissue

article

Identification and in vitro expansion of CD4+ and CD8+ T cells specific for human neutrophil elastase

scientific article published on 4 December 2003

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

scientific article

Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma

scientific article

Immunodominance of HLA-A2-restricted hepatitis C virus-specific CD8+ T cell responses is linked to naive-precursor frequency

scientific article published on 2 March 2011

Immunodominance of HLA-B27-restricted HIV KK10-specific CD8(+) T-cells is not related to naïve precursor frequency

scientific article published on 13 October 2012

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

scientific article

Induction of heterosubtypic cross-protection against influenza by a whole inactivated virus vaccine: the role of viral membrane fusion activity

scientific article

Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface

scientific article published on 18 April 2005

Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression

scientific article

Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.

scientific article published on 20 February 2018

Loss of Viral Control in Early HIV‐1 Infection Is Temporally Associated with Sequential Escape from CD8+T Cell Responses and Decrease in HIV–1–Specific CD4+and CD8+T Cell Frequencies

article

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

scientific article published on 26 February 2010

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

scientific article published on 06 October 2008

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

scientific article published on 19 June 2009

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

scientific article

Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4⁺ T-cell repertoire selection

scientific article published on 7 February 2012

Monoclonal TCR-redirected tumor cell killing.

scientific article

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

scientific article

Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8 T Cells and Evolve at the Population Level

scientific article published on 12 February 2019

Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

scientific article

Naïve CD8 T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8 T-Cells

Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice

scientific article published on December 2011

Novel recombinant Mycobacterium bovis BCG, ovine atadenovirus, and modified vaccinia virus Ankara vaccines combine to induce robust human immunodeficiency virus-specific CD4 and CD8 T-cell responses in rhesus macaques

scientific article

Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural Control of SIV: ANRS SIC Study

scientific article published on 01 September 2020

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

scientific article

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

scientific article published on 4 March 2015

Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response

scientific article published on 04 January 2017

Priming of Qualitatively Superior Human Effector CD8+ T Cells Using TLR8 Ligand Combined with FLT3 Ligand

scientific article published on 25 November 2015

Profound inhibition of antigen-specific T-cell effector functions by dasatinib

scientific article published in April 2008

Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers

scientific article

Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection

scientific article published on 06 April 2009

Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry

scientific article published on 23 July 2006

Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope

scientific article

Reduced naïve CD8(+) T-cell priming efficacy in elderly adults

scientific article

Role of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation.

scientific article published on 5 March 2015

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

scientific article published on 17 April 2007

Simian immunodeficiency virus SIVmac239Deltanef vaccination elicits different Tat28-35SL8-specific CD8+ T-cell clonotypes compared to a DNA prime/adenovirus type 5 boost regimen in rhesus macaques

scientific article published on 26 January 2011

Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques

scientific article published on 9 May 2012

Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

scientific article published on 09 December 2019

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

scientific article

Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus

scientific article

Superior T memory stem cell persistence supports long-lived T cell memory

scientific article published on 2 January 2013

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

scientific article

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

scientific article (publication date: February 2009)

T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

scientific article

T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy

scientific article

T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization

scientific article published on December 2005

TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection

scientific article published on 23 October 2020

TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells

scientific article published on 01 July 2020

Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies.

scientific article published on 17 October 2016

Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers

scientific article published on November 2008

Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+ T cells in chronic infection

scientific article

The HLA A*0201-restricted hTERT(540-548) peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor

scientific article

The Identity of Human Tissue-Emigrant CD8<sup>+</sup> T Cells

scientific article published on 04 December 2020

The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8+ T cells

scientific article published on 04 April 2019

The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro

scientific article published on 15 July 2020

The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression

scientific article published on 10 October 2008

The link between CD8⁺ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate

scientific article published on February 2014

Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire

scientific article published on 12 March 2013

Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans

scientific article published on 12 October 2020

Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity

scientific article

Ultradeep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in simian immunodeficiency virus-infected macaques

scientific article published on 10 June 2009

β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure

scientific article

List of works by Emma Gostick

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

A human memory T cell subset with stem cell-like properties

A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells

AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation, function and EBV immunity.

Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus

Allogeneic HLA-A*02-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuity

Analysis of the functional WT1-specific T-cell repertoire in healthy donors reveals a discrepancy between CD4(+) and CD8(+) memory formation

Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers

Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling

Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective antileukemia reactivity

Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses

Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation

CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold

CMV driven CD8(+) T-cell activation is associated with acute rejection in lung transplantation.

Cellular-level versus receptor-level response threshold hierarchies in T-cell activation

Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency

Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization

Conditional CD8+ T cell escape during acute simian immunodeficiency virus infection

Critical role of TLR7 signaling in the priming of cross-protective cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine

Crystallization and preliminary X-ray structural studies of a Melan-A pMHC-TCR complex

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses.

Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells.

Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.

Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers

Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions

ERAP1 allotypes shape the epitope repertoire of virus-specific CD8+ T cell responses in acute hepatitis C virus infection.

Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers

Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells

Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations

Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

Escape from highly effective public CD8+ T-cell clonotypes by HIV

Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer

Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency

Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239{Delta}nef-vaccinated macaques suppress SIVmac239 replication ex vivo

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor

Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.

GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo

Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response

Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia

HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue

Heterosubtypic cross-protection induced by whole inactivated influenza virus vaccine in mice: influence of the route of vaccine administration

High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow

High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

Holoendemic malaria exposure is associated with altered Epstein-Barr virus-specific CD8(+) T-cell differentiation

Human TCR-binding affinity is governed by MHC class restriction

IL-10 restricts memory T cell inflation during cytomegalovirus infection

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine ⬇️

Identification and In Vitro Expansion of Functional Antigen-Specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection

Identification and characterization of HIV-specific resident memory CD8 + T cells in human lymphoid tissue

Identification and in vitro expansion of CD4+ and CD8+ T cells specific for human neutrophil elastase

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma

Immunodominance of HLA-A2-restricted hepatitis C virus-specific CD8+ T cell responses is linked to naive-precursor frequency

Immunodominance of HLA-B27-restricted HIV KK10-specific CD8(+) T-cells is not related to naïve precursor frequency

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

Induction of heterosubtypic cross-protection against influenza by a whole inactivated virus vaccine: the role of viral membrane fusion activity

Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface

Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression

Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.

Loss of Viral Control in Early HIV‐1 Infection Is Temporally Associated with Sequential Escape from CD8+T Cell Responses and Decrease in HIV–1–Specific CD4+and CD8+T Cell Frequencies

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4⁺ T-cell repertoire selection

Monoclonal TCR-redirected tumor cell killing.

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity