List of works - Karthik Venkatakrishnan

Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidine

scientific article published in March 2003

Drug Metabolism and Drug Interactions: Application and Clinical Value of In Vitro Models ⬇️

scientific article published on October 1, 2003

Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours

scientific article published on 17 May 2019

Evaluation of Supermix as an in vitro model of human liver microsomal drug metabolism

scientific article

Global population pharmacokinetics of the investigational Aurora A kinase inhibitor alisertib in cancer patients: rationale for lower dosage in Asia.

scientific article published on 11 September 2017

In vitro, pharmacokinetic, and pharmacodynamic interactions of ketoconazole and midazolam in the rat.

scientific article published in September 2002

Mechanism of cytochrome P450-3A inhibition by ketoconazole ⬇️

scientific article published on February 1, 2011

Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors

scientific article published in December 2002

Model‐based meta‐analysis using latent variable modeling to set benchmarks for new treatments of systemic lupus erythematosus

scientific article published in 2023

Physiologically-Based Pharmacokinetic Models as Enablers of Precision Dosing in Drug Development: Pivotal Role of the Human Mass Balance Study

scientific article published on 21 November 2020

Population Pharmacokinetics of Brentuximab Vedotin in Adult and Pediatric Patients With Relapsed/Refractory Hematologic Malignancies: Model-Informed Hypothesis Generation for Pediatric Dosing Regimens

scientific article published on 28 June 2020

Population Pharmacokinetics of Brigatinib in Healthy Volunteers and Patients With Cancer

scientific article published on 20 August 2020

Population pharmacokinetics of pevonedistat alone or in combination with standard of care in patients with solid tumours or haematological malignancies

scientific article published on 04 September 2019

Quantitative Translation in Immuno-Oncology Research and Development

scientific article published on 09 July 2020

Role of Physiologically Based Pharmacokinetic Modeling and Simulation in Enabling Model-Informed Development of Drugs and Biotherapeutics

scientific article published on 01 October 2020

Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro

scientific article published on October 2010

Staying Engaged in Your Career Without Burning Out: A Call for Action to Build Resilience

scientific article published on 08 July 2020

List of works by Karthik Venkatakrishnan