List of works - Fabienne Grellepois

Anhydrodihydroartemisinin and its 10-trifluoromethyl analogue: access to novel d-ring-contracted artemisinin trifluoromethyl ketones

scientific article

Asymmetric decarboxylative Claisen rearrangement reactions of sulfoximine-substituted allylic tosylacetic esters

scientific article published in August 2005

Decarboxylative Claisen rearrangement reactions of allylic tosylmalonate esters

scientific article published on 01 February 2005

Design, synthesis and antimalarial activity of trifluoromethylartemisinin-mefloquine dual molecules

scientific article

Diastereoselective Ritter-like Reaction on Cyclic Trifluoromethylated N,O-Acetals Derived from l-Tartaric Acid.

scientific article

Enantiomerically pure 2-aryl(alkyl)-2-trifluoromethylaziridines: synthesis and ring opening with selected O- and N-nucleophiles

scientific article published on 15 December 2010

Enantiopure Trifluoromethylated β3,3-Amino Acids: Synthesis by Asymmetric Reformatsky Reaction with Stable Analogues of Trifluoromethyl N-tert-Butanesulfinylketoimines and Incorporation into α/β-Peptides ⬇️

scientific article published on January 8, 2013

Enantiopure quaternary alpha-trifluoromethyl-alpha-alkoxyaldehydes from L-tartaric acid derived ketoamides

scientific article published on 25 September 2008

First synthesis of 10 alpha-(trifluoromethyl)deoxoartemisinin

scientific article published on 01 March 2002

New fused dithiabicyclic compounds from the reaction of N,N-dialkyl perfluorothioamides with allylmagnesium halides

New three-step domino reaction, "thiophilic addition-beta-elimination of fluoride-[3,3] sigmatropic rearrangement": Synthesis of alpha-allylic and alpha,alpha-bis(allylic) alpha-trifluoromethyl dithioesters

scientific article published on 01 September 2006

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin

scientific article published in March 2004

Organocatalytic enantioselective allylic alkylation of α-aryl γ-lactones: an approach to densely functionalized quaternary stereocentres

scientific article published on 14 May 2020

Synthesis of new artemisinin-derived dimers by self-cross-metathesis reaction

scientific article published on November 2005

The Role of the Counterion and of Silicon Chelation in the Selective Mono(trifluoromethylation) of Tartaric Acid Derived 1,4‐Diketones ⬇️

scientific article published on August 11, 2011

cis-Dihydroxylated α-Trifluoromethylated N,O-Acetal from l-Tartaric Acid: Synthesis of Tetrasubstituted Stereocenter via Diastereoselective Pictet-Spengler Cyclization of N-Acyliminium Ions

scientific article published on 26 July 2020

α-Trifluoromethylated tertiary homoallylic amines: diastereoselective synthesis and conversion into β-aminoesters, γ- and δ-aminoalcohols, azetidines and pyrrolidines

scientific article published on 10 November 2017

List of works by Fabienne Grellepois

Anhydrodihydroartemisinin and its 10-trifluoromethyl analogue: access to novel d-ring-contracted artemisinin trifluoromethyl ketones

Asymmetric decarboxylative Claisen rearrangement reactions of sulfoximine-substituted allylic tosylacetic esters

Decarboxylative Claisen rearrangement reactions of allylic tosylmalonate esters

Design, synthesis and antimalarial activity of trifluoromethylartemisinin-mefloquine dual molecules

Diastereoselective Ritter-like Reaction on Cyclic Trifluoromethylated N,O-Acetals Derived from l-Tartaric Acid.

Enantiomerically pure 2-aryl(alkyl)-2-trifluoromethylaziridines: synthesis and ring opening with selected O- and N-nucleophiles

Enantiopure Trifluoromethylated β3,3-Amino Acids: Synthesis by Asymmetric Reformatsky Reaction with Stable Analogues of Trifluoromethyl N-tert-Butanesulfinylketoimines and Incorporation into α/β-Peptides ⬇️

Enantiopure quaternary alpha-trifluoromethyl-alpha-alkoxyaldehydes from L-tartaric acid derived ketoamides

First synthesis of 10 alpha-(trifluoromethyl)deoxoartemisinin

New fused dithiabicyclic compounds from the reaction of N,N-dialkyl perfluorothioamides with allylmagnesium halides

New three-step domino reaction, "thiophilic addition-beta-elimination of fluoride-[3,3] sigmatropic rearrangement": Synthesis of alpha-allylic and alpha,alpha-bis(allylic) alpha-trifluoromethyl dithioesters

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin

Organocatalytic enantioselective allylic alkylation of α-aryl γ-lactones: an approach to densely functionalized quaternary stereocentres

Synthesis of new artemisinin-derived dimers by self-cross-metathesis reaction

The Role of the Counterion and of Silicon Chelation in the Selective Mono(trifluoromethylation) of Tartaric Acid Derived 1,4‐Diketones ⬇️

cis-Dihydroxylated α-Trifluoromethylated N,O-Acetal from l-Tartaric Acid: Synthesis of Tetrasubstituted Stereocenter via Diastereoselective Pictet-Spengler Cyclization of N-Acyliminium Ions

α-Trifluoromethylated tertiary homoallylic amines: diastereoselective synthesis and conversion into β-aminoesters, γ- and δ-aminoalcohols, azetidines and pyrrolidines