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List of works by André Pèlegrin

A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions

scientific article published on 18 February 2019

An auristatin-based antibody-drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer

scientific article published on 01 April 2019

Antibody-drug conjugates: Design and development for therapy and imaging in and beyond cancer, LabEx MAbImprove industrial workshop, July 27-28, 2017, Tours, France

scientific article published on 14 December 2017

Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.

scientific article published on 4 May 2016

Combined radioimmunotherapy and chemotherapy of human colon carcinoma grafted in nude mice, advantages and limitations

scientific article published on July 1, 1992

Different behaviour of mouse-human chimeric antibody F(ab')2 fragments of IgG1, IgG2 and IgG4 sub-classin vivo ⬇️

scientific article published on 01 February 1992

Elimination of Free Radionuclide by a Chelating Agent Improves Tumor-to-Nontumor Ratios Following Radioimmunotargeting with Antibody Labeled with 67Ga ⬇️

scientific article published on April 1, 1998

Higher Anti-Tumor Efficacy of the Dual HER3-EGFR Antibody MEHD7945a Combined with Ionizing Irradiation in Cervical Cancer Cells

scientific article published on 17 January 2020

ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells

scientific article published on 23 August 2019

Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent

scientific article published on 26 July 2018

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

scientific article published on 04 February 2019

MAbImprove: a French "Laboratoire d'excellence" (LabEx) dedicated to therapeutic antibodies

scientific article published on 16 May 2014

Marked increase in the secretion of a fully antigenic recombinant carcinoembryonic antigen obtained by deletion of its hydrophobic tail ⬇️

scientific article published on July 1, 1993

Multimodal CEA-targeted image-guided colorectal cancer surgery using 111In-labeled SGM-101

scientific article published on 08 September 2020

Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3.

scientific article published on 15 May 2017

Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples

scientific article published on 03 December 2019

Quantitative proteomic analysis reveals AK2 as potential biomarker for late normal tissue radiotoxicity

scientific article published on 09 August 2019

Radiolabeled monoclonal antibodies as anti-tumor missiles, their diagnostic success and therapeutic potential

scientific article published on June 1, 1992

SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery

scientific article published on 09 March 2017

Safety and effectiveness of SGM-101, a fluorescent antibody targeting carcinoembryonic antigen, for intraoperative detection of colorectal cancer: a dose-escalation pilot study

scientific article published on 17 January 2018

T lymphocytes to predict radiation-induced late effects in normal tissues.

scientific article published on 11 December 2016

Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer

scientific article published in September 2018

Targets for MAbs: innovative approaches for their discovery & validation, LabEx MAbImprove 6th antibody industrial symposium, June 25-26, 2018, Montpellier, France

scientific article published on 16 May 2019

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

scientific article published on 18 May 2016

The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

scientific article

The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages.

scientific article published on 7 October 2017

Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis

scientific article

Toxicity and pharmacokinetic profile of SGM-101, a fluorescent anti-CEA chimeric antibody for fluorescence imaging of tumors in patients

article

[A word from the coordinators]

scientific article published on 01 December 2019

[Antibodies, tools of choice for fluorescence-guided surgery]

scientific article published on 01 December 2019

[Players from the program "Investments for the Future": MAbImprove MabEx]

scientific article published on 01 December 2019

[Radioimmunotherapy: the reasons for confidential clinical use and hope for development]

scientific article published on 01 December 2019

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