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List of works by Douglas J Winton

Apc deficiency predisposes to renal carcinoma in the mouse

Bcl-2 is a critical mediator of intestinal transformation

scientific article published on 9 March 2016

Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells

scientific journal article

Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas.

scientific article

Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine

scientific article published on 9 June 2005

Defining stem cell dynamics in models of intestinal tumor initiation

scientific article published in November 2013

Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation

scientific article

Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.

scientific article published on August 2010

Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing

scientific article published on 22 October 2020

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

scientific journal article

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

scientific article

Itraconazole targets cell cycle heterogeneity in colorectal cancer.

scientific article

Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine

scientific article

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

scientific journal article

PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine

scientific article published in November 2004

Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-Deficient Murine Epithelium

scientific article published on 24 May 2019

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