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List of works by Yogen Saunthararajah

Clinical effectiveness of decitabine in severe sickle cell disease

scientific article published in April 2008

Clinical studies with fetal hemoglobin-enhancing agents in sickle cell disease

scientific article

Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia

scientific article published on 07 September 2020

Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis

scientific article published on 03 April 2019

Cytoplasmic dislocation of NPM1 and PU.1 in NPM1-mutated leukaemia is obscured by paraformaldehyde fixation

scientific article published on 29 February 2020

DNA hypo-methylating agents and sickle cell disease

scientific article published in September 2004

Decitabine- and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network

scientific article published on 07 August 2020

Effect of AGM and Fetal Liver-Derived Stromal Cell Lines on Globin Expression in Adult Baboon (P. anubis) Bone Marrow-Derived Erythroid Progenitors

scientific article published on May 31, 2012

Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease

scientific article published on 7 August 2003

Extended experience with a non-cytotoxic DNMT1-targeting regimen of decitabine to treat myeloid malignancies

scientific article published on 17 November 2019

Hemoglobinopathies

scientific article published on January 2003

Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A.

scientific article published on 19 February 2004

Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons

scientific article published on 17 August 2018

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.

scientific article published on 7 September 2017

S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)

scientific article published on 8 October 2010

Severe pyoderma gangrenosum caused by myelodysplastic syndrome successfully treated with decitabine administered by a noncytotoxic regimen

scientific article

Standard clinical practice underestimates the role and significance of erythropoietin deficiency in sickle cell disease

scientific article published on March 21, 2011

The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice

scientific article published in June 2015

The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis).

scientific article published on 8 February 2016