List of works - Daniela Parolaro

A molecular basis of analgesic tolerance to cannabinoids.

scientific article published on April 2007

AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.

scientific article

Adolescent THC exposure in female rats leads to cognitive deficits through a mechanism involving chromatin modifications in the prefrontal cortex.

scientific article

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

scientific article published on 2 October 2014

Adolescent exposure to cannabis as a risk factor for psychiatric disorders ⬇️

scientific article published on July 18, 2011

Adult Cellular Neuroadaptations Induced by Adolescent THC Exposure in Female Rats Are Rescued by Enhancing Anandamide Signaling

scientific article published on 01 November 2018

Alterations of prefrontal cortex GABAergic transmission in the complex psychotic-like phenotype induced by adolescent delta-9-tetrahydrocannabinol exposure in rats

scientific article

Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat

scientific article

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines

scientific article published on 14 November 2003

Assay of GTPγS Binding in Autoradiography.

scientific article

Bidirectional regulation of mu-opioid and CB1-cannabinoid receptor in rats self-administering heroin or WIN 55,212-2.

scientific article

Binding of δ9-tetrahydrocannabinol and diazepam to human serum albumin

scientific article published on 9 May 2011

Cannabidiol as potential anticancer drug

scientific article

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism.

scientific article published on April 2005

Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect

scientific article (publication date: 2013)

Cannabidivarin Treatment Ameliorates Autism-Like Behaviors and Restores Hippocampal Endocannabinoid System and Glia Alterations Induced by Prenatal Valproic Acid Exposure in Rats

scientific article published on 09 August 2019

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice

scientific article published on 14 May 2019

Cannabimimetic activity, binding, and degradation of stearoylethanolamide within the mouse central nervous system

scientific article published in September 2002

Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine

scientific article published on 3 March 2010

Cannabinoids and opioids share cAMP pathway in rat splenocytes

scientific article

Cannabinoids as potential new therapy for the treatment of gliomas

scientific article

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

scientific article

Cellular mechanisms underlying the anxiolytic effect of low doses of peripheral Delta9-tetrahydrocannabinol in rats

scientific article published on 7 February 2007

Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine

scientific article published in October 2004

Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood

scientific article published in August 2009

Changes in the expression of G protein-coupled receptor kinases and beta-arrestins in mouse brain during cannabinoid tolerance: a role for RAS-ERK cascade.

scientific article published in June 2006

Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates.

scientific article published on 2 January 2008

Chronic morphine modulates the contents of the endocannabinoid, 2-arachidonoyl glycerol, in rat brain.

scientific article published on 12 March 2003

Chronic nandrolone decanoate exposure during adolescence affects emotional behavior and monoaminergic neurotransmission in adulthood

scientific article

Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat: Part 1: Effects on somatic growth, growth hormone-axis activity and bone mass in the offspring

scientific journal article

Chronic treatment with the endocannabinoid anandamide increases cytochrome P450 metabolizing system in the rat.

scientific article published in August 2002

Comparative analysis of molecular strategies attenuating positional effects in lentiviral vectors carrying multiple genes.

scientific article published on 11 May 2006

Cortical neuroinflammation contributes to long-term cognitive dysfunctions following adolescent delta-9-tetrahydrocannabinol treatment in female rats

scientific article

ERK-dependent modulation of cerebellar synaptic plasticity after chronic Delta9-tetrahydrocannabinol exposure.

scientific article published in May 2006

Endocannabinoids and Mental Disorders

scientific article published on January 2015

Endocannabinoids and drug dependence

scientific article published in December 2005

Endocannabinoids in the immune system and cancer.

scientific article published in February 2002

Estrogenic effect of procymidone through activation of MAPK in MCF-7 breast carcinoma cell line.

scientific article published on 28 November 2005

Expression and function of the endocannabinoid system in glial cells

scientific article published on January 2008

Intrauterine position has long-term influence on brain mu-opioid receptor density and behaviour in mice

scientific article

Involvement of kappa-opioid and endocannabinoid system on Salvinorin A-induced reward

scientific article

Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia

scientific article

Is cannabinoid transmission involved in rewarding properties of drugs of abuse?

scientific article published in August 2002

Lifelong imbalanced LA/ALA intake impairs emotional and cognitive behavior via changes in brain endocannabinoid system

scientific article

Long-lasting recovery of psychotic-like symptoms in isolation-reared rats after chronic but not acute treatment with the cannabinoid antagonist AM251

scientific article published on 06 October 2010

Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas

scientific article published on 24 December 2008

Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats.

scientific article

MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.

scientific article

Modulation of extracellular signal-regulated kinases cascade by chronic delta 9-tetrahydrocannabinol treatment

scientific article published in March 2004

Molecular and cellular basis of cannabinoid and opioid interactions.

scientific article

Molecular mechanisms involved in the antitumor activity of cannabinoids on gliomas: role for oxidative stress

scientific article

Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems

scientific article

Neurobiological mechanisms underlying cannabis-induced memory impairment

scientific article published on 02 March 2020

New vistas on cannabis use disorder

scientific article

Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw.

scientific article published on 12 February 2004

Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: a neurobehavioral model of autism

scientific article published on 21 February 2011

Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia divinorum, in rodents

scientific article

Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects.

scientific article published in May 2005

Role of endocannabinoids in regulating drug dependence

scientific article published on December 2007

SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance ⬇️

scientific article published on January 8, 2012

Sex-dependent changes in brain CB1R expression and functionality and immune CB2R expression as a consequence of maternal deprivation and adolescent cocaine exposure

scientific article published on 14 May 2013

Sex-dependent vulnerability to cannabis abuse in adolescence.

scientific article

Sexually dimorphic effects of cannabinoid compounds on emotion and cognition.

scientific article

The Endocannabinoid System and Autism Spectrum Disorders: Insights from Animal Models.

scientific article published on 7 September 2017

The Impact of Exposure to Cannabinoids in Adolescence: Insights From Animal Models.

scientific article published on 07 August 2015

The anabolic steroid nandrolone alters cannabinoid self-administration and brain CB1 receptor density and function

scientific article published on 24 November 2016

The endocannabinoid system and psychiatric disorders

scientific article

The endocannabinoid system and schizophrenia: integration of evidence

scientific article published on January 1, 2012

The phytocannabinoid, Δ⁹-tetrahydrocannabivarin, can act through 5-HT₁A receptors to produce antipsychotic effects.

scientific article

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

scientific article

Transcriptomic and proteomic analyses of mouse cerebellum reveals alterations in RasGRF1 expression following in vivo chronic treatment with delta 9-tetrahydrocannabinol.

scientific article

List of works by Daniela Parolaro

A molecular basis of analgesic tolerance to cannabinoids.

AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.

Adolescent THC exposure in female rats leads to cognitive deficits through a mechanism involving chromatin modifications in the prefrontal cortex.

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

Adolescent exposure to cannabis as a risk factor for psychiatric disorders ⬇️

Adult Cellular Neuroadaptations Induced by Adolescent THC Exposure in Female Rats Are Rescued by Enhancing Anandamide Signaling

Alterations of prefrontal cortex GABAergic transmission in the complex psychotic-like phenotype induced by adolescent delta-9-tetrahydrocannabinol exposure in rats

Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines

Assay of GTPγS Binding in Autoradiography.

Bidirectional regulation of mu-opioid and CB1-cannabinoid receptor in rats self-administering heroin or WIN 55,212-2.

Binding of δ9-tetrahydrocannabinol and diazepam to human serum albumin

Cannabidiol as potential anticancer drug

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism.

Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect

Cannabidivarin Treatment Ameliorates Autism-Like Behaviors and Restores Hippocampal Endocannabinoid System and Glia Alterations Induced by Prenatal Valproic Acid Exposure in Rats

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice

Cannabimimetic activity, binding, and degradation of stearoylethanolamide within the mouse central nervous system

Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine

Cannabinoids and opioids share cAMP pathway in rat splenocytes

Cannabinoids as potential new therapy for the treatment of gliomas

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

Cellular mechanisms underlying the anxiolytic effect of low doses of peripheral Delta9-tetrahydrocannabinol in rats

Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine

Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood

Changes in the expression of G protein-coupled receptor kinases and beta-arrestins in mouse brain during cannabinoid tolerance: a role for RAS-ERK cascade.

Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates.

Chronic morphine modulates the contents of the endocannabinoid, 2-arachidonoyl glycerol, in rat brain.

Chronic nandrolone decanoate exposure during adolescence affects emotional behavior and monoaminergic neurotransmission in adulthood

Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat: Part 1: Effects on somatic growth, growth hormone-axis activity and bone mass in the offspring

Chronic treatment with the endocannabinoid anandamide increases cytochrome P450 metabolizing system in the rat.

Comparative analysis of molecular strategies attenuating positional effects in lentiviral vectors carrying multiple genes.

Cortical neuroinflammation contributes to long-term cognitive dysfunctions following adolescent delta-9-tetrahydrocannabinol treatment in female rats

ERK-dependent modulation of cerebellar synaptic plasticity after chronic Delta9-tetrahydrocannabinol exposure.

Endocannabinoids and Mental Disorders

Endocannabinoids and drug dependence

Endocannabinoids in the immune system and cancer.

Estrogenic effect of procymidone through activation of MAPK in MCF-7 breast carcinoma cell line.

Expression and function of the endocannabinoid system in glial cells

Intrauterine position has long-term influence on brain mu-opioid receptor density and behaviour in mice

Involvement of kappa-opioid and endocannabinoid system on Salvinorin A-induced reward

Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia

Is cannabinoid transmission involved in rewarding properties of drugs of abuse?

Lifelong imbalanced LA/ALA intake impairs emotional and cognitive behavior via changes in brain endocannabinoid system

Long-lasting recovery of psychotic-like symptoms in isolation-reared rats after chronic but not acute treatment with the cannabinoid antagonist AM251

Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas

Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats.

MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.

Modulation of extracellular signal-regulated kinases cascade by chronic delta 9-tetrahydrocannabinol treatment

Molecular and cellular basis of cannabinoid and opioid interactions.

Molecular mechanisms involved in the antitumor activity of cannabinoids on gliomas: role for oxidative stress

Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems

Neurobiological mechanisms underlying cannabis-induced memory impairment

New vistas on cannabis use disorder

Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw.

Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: a neurobehavioral model of autism

Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia divinorum, in rodents

Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects.

Role of endocannabinoids in regulating drug dependence

SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance ⬇️

Sex-dependent changes in brain CB1R expression and functionality and immune CB2R expression as a consequence of maternal deprivation and adolescent cocaine exposure

Sex-dependent vulnerability to cannabis abuse in adolescence.

Sexually dimorphic effects of cannabinoid compounds on emotion and cognition.

The Endocannabinoid System and Autism Spectrum Disorders: Insights from Animal Models.

The Impact of Exposure to Cannabinoids in Adolescence: Insights From Animal Models.

The anabolic steroid nandrolone alters cannabinoid self-administration and brain CB1 receptor density and function

The endocannabinoid system and psychiatric disorders

The endocannabinoid system and schizophrenia: integration of evidence

The phytocannabinoid, Δ⁹-tetrahydrocannabivarin, can act through 5-HT₁A receptors to produce antipsychotic effects.

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

Transcriptomic and proteomic analyses of mouse cerebellum reveals alterations in RasGRF1 expression following in vivo chronic treatment with delta 9-tetrahydrocannabinol.