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List of works by Hilda A Pickett

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

scientific article published on 8 June 2015

Abstract 5209: Efficacious targeting of TERT oncogene rearrangement with BET bromodomain inhibitor and proteasome inhibitor combination therapy

scholarly article

Age Adjusted Telomere Length Decreases Following Treatment for Pediatric Acute Lymphoblastic Leukemia, but Does Not Predict Toxicity ⬇️

scholarly article

Age-Adjusted Telomere Length May Predict Treatment-Related Mortality in Children Undergoing Hematopoietic Stem Cell Transplantation ⬇️

scholarly article

Alternative Lengthening of Telomeres: DNA Repair Pathways Converge.

scientific article

Alternative lengthening of telomeres in normal mammalian somatic cells

scientific article published on January 2013

Alternative lengthening of telomeres: remodeling the telomere architecture

scientific article published on 20 February 2013

Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels

scientific article

Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair

scientific article published on 01 December 2021

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

scientific article published on 10 October 2017

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

scientific article published on 20 November 2019

BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres.

scientific article

Comparative analysis of whole genome sequencing-based telomere length measurement techniques

scientific article

Control of telomere length by a trimming mechanism that involves generation of t-circles

scientific article published on 12 February 2009

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours

scientific article published on 27 September 2017

DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts

scientific article published on 14 August 2019

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity

scientific article published on 01 December 2009

Dyskerin Is Upregulated During Erythroid Differentiation of Human Hematopoietic Progenitor Cells and Hyperactivates Telomerase in Erythroid Precursor Cells ⬇️

scholarly article

Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes

scientific article published on 27 December 2019

Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells

scientific article published on 22 July 2019

Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres.

scientific article published in June 2017

Extreme telomere length dimorphism in the Tasmanian devil and related marsupials suggests parental control of telomere length

scientific article

FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops

scientific article published on 13 December 2019

Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells

scientific article published on 19 November 2013

Functional dissection of breast cancer risk-associated TERT promoter variants

scientific article published on 26 May 2017

Functional polymorphisms in the TERT promoter are associated with risk of serious ovarian and breast cancer

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers

scientific article

Heritable defects in telomere and mitotic function selectively predispose to sarcomas

scientific article published on 20 January 2023

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres

scientific article

Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline

scientific article published on 5 August 2009

Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1.

scientific article

Loss-of-function variants in POT1 predispose to uveal melanoma

scientific article published on 09 September 2020

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.

scientific article published on 13 April 2016

Mechanisms that drive telomere maintenance and recombination in human cancers

scientific article published on 28 February 2020

Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells

scientific article published on 4 February 2002

Molecular mechanisms of activity and derepression of alternative lengthening of telomeres

scientific article

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Normal mammalian cells negatively regulate telomere length by telomere trimming ⬇️

scientific article published on September 8, 2011

NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.

scientific article published on 24 August 2014

Platelet Derived Growth Factor Receptor-Alpha expressing cardiac progenitor cells can be derived from previously cryopreserved human heart samples.

scientific article published on 5 December 2017

Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools

scientific article published on 23 June 2021

RTEL1 contributes to DNA replication and repair and telomere maintenance.

scientific article

Replication stress tolerance and management differs between naïve and primed pluripotent cells

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

scientific article published on 22 November 2009

Structural and functional characterization of the RBBP4-ZNF827 interaction and its role in NuRD recruitment to telomeres

scientific article published on 31 August 2018

Targeted therapy of <i>TERT</i>-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy

scientific article published on 11 December 2020

Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription

scientific article published on 07 January 2009

Telomerase promotes formation of a telomere protective complex in cancer cells

scientific article published on 02 October 2019

Telomerase recruitment requires both TCAB1 and Cajal bodies independently

scientific article

Telomere Length Measurement by Molecular Combing

scientific article published on 16 June 2020

Telomere Loop Dynamics in Chromosome End Protection

scientific article published on 19 July 2018

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes

scientific article

Telomere sequence content can be used to determine ALT activity in tumours

scientific article published on 30 April 2018

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

scientific article published in 2024

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

scientific article published on 28 May 2019

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly

scientific article published on 23 January 2020

The role of telomere trimming in normal telomere length dynamics

scientific article published on April 2012

The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak.

scientific article published on 17 October 2013

Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells.

scientific article

Whole-genome landscape of pancreatic neuroendocrine tumours.

scientific article published on 15 February 2017

Whole-genome landscapes of major melanoma subtypes.

scientific article published on 3 May 2017

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