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List of works by Leo C James

1-15 of 15 results

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Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

scientific article published in April 2004
IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis

article
Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.

scientific article
Complement C4 Prevents Viral Infection through Capsid Inactivation

scientific article published on 26 March 2019
Beta-edge interactions in a pentadecameric human antibody V kappa domain

scientific article
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

scientific article published on 29 August 2019
Intracellular neutralisation of rotavirus by VP6-specific IgG

scientific article published on 04 August 2020
Intracellular antibody immunity and its applications

scientific article published on 06 August 2020
RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination

scientific article published on 22 February 2021
Target-induced clustering activates Trim-Away of pathogens and proteins

scientific article published on 25 February 2021
Rare missense variants in the human cytosolic antibody receptor preserve antiviral function

scientific article published on 15 October 2019
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models

A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly

scientific article published on 01 February 2021
Aggregate-selective removal of pathological tau by clustering-activated degraders

scientific article published on 30 August 2024
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

scientific article published on 01 December 2020

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