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List of works by Fátima Al-Shahrour

A comprehensive database for integrated analysis of omics data in autoimmune diseases

scientific article published on 24 June 2021

A function-centric approach to the biological interpretation of microarray time-series

scientific article published in January 2006

A large scale survey reveals that chromosomal copy-number alterations significantly affect gene modules involved in cancer initiation and progression.

scientific article

A molecular hypothesis to explain direct and inverse co-morbidities between Alzheimer's Disease, Glioblastoma and Lung cancer

scientific article

A user guide for the online exploration and visualization of PCAWG data

scientific article published on 07 July 2020

An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection

scientific article published on 31 January 2022

Analysis of normal-tumour tissue interaction in tumours: prediction of prostate cancer features from the molecular profile of adjacent normal cells

scientific article

BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments.

scientific article

BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments.

scientific article published on July 2006

Babelomics: advanced functional profiling of transcriptomics, proteomics and genomics experiments

scientific article published on 31 May 2008

Beyondcell: targeting cancer therapeutic heterogeneity in single-cell RNA-seq data

scientific article published on 16 December 2021

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.

scientific article

CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC

scientific article published on 04 July 2019

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

scientific article

Clonal dynamics monitoring during clinical evolution in chronic lymphocytic leukaemia

scientific article published in Scientific Reports

Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

scientific article published on 08 April 2019

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

scientific article published on April 2016

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.

scientific article

DBAli tools: mining the protein structure space

scientific article

DREIMT: a drug repositioning database and prioritization tool for immunomodulation

scientific article published on 20 August 2020

Dexamethasone and lenalidomide have distinct functional effects on erythropoiesis

scientific article

Discovering molecular functions significantly related to phenotypes by combining gene expression data and biological information

scientific article

Discovery of new targets to control metastasis in pancreatic cancer by single cell transcriptomics analysis of circulating tumor cells

scientific article published on 04 June 2020

Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera ⬇️

scientific article published on May 24, 2012

Endothelin-1-mediated Drug Resistance in EGFR-mutant NSCLC

scientific article published on 03 August 2020

Evidence for systems-level molecular mechanisms of tumorigenesis

scientific article

Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli

scientific article published in March 2009

Expression and microarrays.

scientific article published in January 2008

FatiGO +: a functional profiling tool for genomic data. Integration of functional annotation, regulatory motifs and interaction data with microarray experiments

scientific article

From genes to functional classes in the study of biological systems

scientific article

Functional profiling and gene expression analysis of chromosomal copy number alterations

scientific article published on 10 April 2007

Functional profiling of microarray experiments using text-mining derived bioentities

scientific article published on 13 September 2007

Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

scientific article

Functional signatures identified in B-cell non-Hodgkin lymphoma profiles.

scientific article published on October 2009

GEPAS, a web-based tool for microarray data analysis and interpretation

scientific article

GEPAS, an experiment-oriented pipeline for the analysis of microarray gene expression data

scientific article

GEPAS: A web-based resource for microarray gene expression data analysis

scientific article

Gene set internal coherence in the context of functional profiling

scientific article

Gene set-based analysis of polymorphisms: finding pathways or biological processes associated to traits in genome-wide association studies

scientific article published on 05 June 2009

Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation

scientific article published on 01 December 2019

Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing

scientific article published on 28 August 2019

ISACGH: a web-based environment for the analysis of Array CGH and gene expression which includes functional profiling.

scientific article published on 27 April 2007

Immunophenotype and Transcriptome Profile of Patients With Multiple Sclerosis Treated With Fingolimod: Setting Up a Model for Prediction of Response in a 2-Year Translational Study

scientific article published on 25 July 2018

In Silico Drug Prescription for Targeting Cancer Patient Heterogeneity and Prediction of Clinical Outcome

scientific article published on 13 September 2019

In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling

scientific article published on 13 June 2013

Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis

scientific article

Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment

scientific article

Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma

scientific article published on 09 July 2019

Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships

scientific article published on 05 June 2020

Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition

scientific article

Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells

scientific article published on 7 July 2011

MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C.

scientific article published on 15 February 2016

Metatax: Metataxonomics with a Compi-Based Pipeline for Precision Medicine

scientific article published on 30 April 2020

Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state

scientific article published on 19 October 2020

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

scientific article published on 06 January 2014

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

scientific article

Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation ⬇️

scientific article published on 7 March 2016

New challenges in gene expression data analysis and the extended GEPAS

scientific article

Next station in microarray data analysis: GEPAS.

scientific article

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells

scientific article

Ontology-driven approaches to analyzing data in functional genomics

scientific article

PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data.

scientific article

Pancreas Cancer Precision Treatment Using Avatar Mice from a Bioinformatics Perspective

scientific article published in September 2017

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics

scientific article published on 25 May 2017

Precision medicine needs pioneering clinical bioinformaticians.

scientific article published on 25 October 2017

PupaSNP Finder: a web tool for finding SNPs with putative effect at transcriptional level.

scientific article published on July 2004

SNOW, a web-based tool for the statistical analysis of protein-protein interaction networks

scientific article published on 19 May 2009

Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

scientific article published on 19 January 2018

Selection upon genome architecture: conservation of functional neighborhoods with changing genes

scientific article

Stromal EGF and igf-I together modulate plasticity of disseminated triple-negative breast tumors.

scientific article published on 20 May 2013

Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.

scientific article published on 31 August 2016

Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor

scientific article

Temporal Molecular and Biological Assessment of an Erlotinib-Resistant Lung Adenocarcinoma Model Reveals Markers of Tumor Progression and Treatment Response ⬇️

scientific article published on September 11, 2012

The AnnoLite and AnnoLyze programs for comparative annotation of protein structures.

scientific article

The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.

scientific article

The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion.

scientific article published on 15 January 2013

The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data

scientific article published on 26 October 2019

Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin.

scientific article published on 13 June 2017

Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer

article

vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer

scientific article published on 01 November 2019

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