List of works - Wayne F. Anderson

Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation

scientific article

Acetylation of the response regulator RcsB controls transcription from a small RNA promoter

scientific article published on 12 July 2013

Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL Domains

scientific article

Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases

scientific article

Structural and Molecular Mechanism for Autoprocessing of MARTX Toxin of Vibrio cholerae at Multiple Sites

scientific article

An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 β-Glycosidase fromThermotoga maritima

article

Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus

scientific article (publication date: March 2017)

Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction

scientific article

Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae

scientific article

The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites

scientific article

Targeting human central nervous system protein kinases: An isoform selective p38αMAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models.

scientific article

Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments

scientific article

Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity

scientific journal article

Complexes of RecA with LexA and RecX differentiate between active and inactive RecA nucleoprotein filaments

scientific article

Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis

scientific article published in September 2004

Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein from Enterococcus faecalis and Crystal Structure of the Activator-Substrate Complex

scientific article

Role of the membrane localization domain of the Pseudomonas aeruginosa effector protein ExoU in cytotoxicity

scientific article

Structure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcU

scientific article

NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: structural insight into specificity for phospho-beta-D-glucosides

scientific article

Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition

scientific article

Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes

scientific article

Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.

scientific article

The diversity of allosteric controls at the gateway to aromatic amino acid biosynthesis

scientific article published on 08 March 2013

Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa

scientific article

Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain

scientific article

Insights into the Mechanism of Type I Dehydroquinate Dehydratases from Structures of Reaction Intermediates

scientific article

Automated crystallographic system for high-throughput protein structure determination

scientific article

Crystal structure of anapoform ofShigella flexneriArsH protein with an NADPH-dependent FMN reductase activity

scientific article

Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain

scientific article

The 2.2 Å resolution crystal structure ofBacillus cereusNif3-family protein YqfO reveals a conserved dimetal-binding motif and a regulatory domain

scientific article

A Novel Phosphatidylinositol 4,5-Bisphosphate Binding Domain Mediates Plasma Membrane Localization of ExoU and Other Patatin-like Phospholipases

scientific article published on December 10, 2014

Structure-Based Mutational Studies of Substrate Inhibition of Betaine Aldehyde Dehydrogenase BetB from Staphylococcus aureus

scientific article

Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

scientific article

Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation

scientific article

Large Scale Structural Rearrangement of a Serine Hydrolase from Francisella tularensis Facilitates Catalysis

scientific article

The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling

article

A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure

scientific journal article

YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology

scientific article published on 01 December 2004

A Conserved Surface Loop in Type I Dehydroquinate Dehydratases Positions an Active Site Arginine and Functions in Substrate Binding

scientific article

Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis

scientific article published on July 2016

An acetylatable lysine controls CRP function in E. coli.

scientific article

Adherence to Bürgi–Dunitz stereochemical principles requires significant structural rearrangements in Schiff-base formation: insights from transaldolase complexes

scientific article

Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance

scientific article

Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP.

scientific article published on 13 January 2014

The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions

scientific article

Mechanisms of Allosteric Activation and Inhibition of the Deoxyribonucleoside Triphosphate Triphosphohydrolase from Enterococcus faecalis

scientific article

Crystal structure of YfiR, an unusual TetR/CamR-type putative transcriptional regulator from Bacillus subtilis

scientific article published on 01 October 2006

Crystal structure of Bacillus subtilis YdaF protein: a putative ribosomal N-acetyltransferase.

scientific article published on December 2004

Discovery of selective inhibitors of the Clostridium difficile dehydroquinate dehydratase

scientific article

Structure to function of an α-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis.

scientific article published on 7 November 2016

List of works by Wayne F. Anderson

Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation

Acetylation of the response regulator RcsB controls transcription from a small RNA promoter

Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL Domains

Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases

Structural and Molecular Mechanism for Autoprocessing of MARTX Toxin of Vibrio cholerae at Multiple Sites

An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 β-Glycosidase fromThermotoga maritima

Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus

Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction

Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae

The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites

Targeting human central nervous system protein kinases: An isoform selective p38αMAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models.

Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments

Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity

Complexes of RecA with LexA and RecX differentiate between active and inactive RecA nucleoprotein filaments

Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis

Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein from Enterococcus faecalis and Crystal Structure of the Activator-Substrate Complex

Role of the membrane localization domain of the Pseudomonas aeruginosa effector protein ExoU in cytotoxicity

Structure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcU

NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: structural insight into specificity for phospho-beta-D-glucosides

Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition

Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes

Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.

The diversity of allosteric controls at the gateway to aromatic amino acid biosynthesis

Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa

Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain

Insights into the Mechanism of Type I Dehydroquinate Dehydratases from Structures of Reaction Intermediates

Automated crystallographic system for high-throughput protein structure determination

Crystal structure of anapoform ofShigella flexneriArsH protein with an NADPH-dependent FMN reductase activity

Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain

The 2.2 Å resolution crystal structure ofBacillus cereusNif3-family protein YqfO reveals a conserved dimetal-binding motif and a regulatory domain

A Novel Phosphatidylinositol 4,5-Bisphosphate Binding Domain Mediates Plasma Membrane Localization of ExoU and Other Patatin-like Phospholipases

Structure-Based Mutational Studies of Substrate Inhibition of Betaine Aldehyde Dehydrogenase BetB from Staphylococcus aureus

Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation

Large Scale Structural Rearrangement of a Serine Hydrolase from Francisella tularensis Facilitates Catalysis

The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling

A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure

YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology

A Conserved Surface Loop in Type I Dehydroquinate Dehydratases Positions an Active Site Arginine and Functions in Substrate Binding

Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis

An acetylatable lysine controls CRP function in E. coli.

Adherence to Bürgi–Dunitz stereochemical principles requires significant structural rearrangements in Schiff-base formation: insights from transaldolase complexes

Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance

Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP.

The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions

Mechanisms of Allosteric Activation and Inhibition of the Deoxyribonucleoside Triphosphate Triphosphohydrolase from Enterococcus faecalis

Crystal structure of YfiR, an unusual TetR/CamR-type putative transcriptional regulator from Bacillus subtilis

Crystal structure of Bacillus subtilis YdaF protein: a putative ribosomal N-acetyltransferase.

Discovery of selective inhibitors of the Clostridium difficile dehydroquinate dehydratase

Structure to function of an α-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis.