List of works - R Katherine Alpaugh

A Phase I/II study of suberoylanilide hydroxamic acid (SAHA) in combination with trastuzumab (Herceptin) in patients with advanced metastatic and/or local chest wall recurrent HER2-amplified breast cancer: a trial of the ECOG-ACRIN Cancer Research G

scientific article published on 16 June 2017

A phase I-II study of the histone deacetylase inhibitor vorinostat plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in locally advanced breast cancer

scientific article

A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: a Gynecologic Oncology Group study

scientific article published on 23 August 2012

A phase II trial of the proteasome inhibitor bortezomib in patients with advanced biliary tract cancers

scientific article

An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression.

scientific article published on 20 June 2013

Biodistribution and Radiation Dosimetry of the Integrin Marker 18F-RGD-K5 Determined from Whole-Body PET/CT in Monkeys and Humans ⬇️

scientific article published on April 12, 2012

Biodistribution and radiation dosimetry of the hypoxia marker 18F–HX4 in monkeys and humans determined by using whole-body PET/CT ⬇️

scientific article published on December 1, 2010

Blocking NK cell inhibitory self-recognition promotes antibody-dependent cellular cytotoxicity in a model of anti-lymphoma therapy

scientific article

Circulating Cancer-Associated Macrophage-Like Cells Differentiate Malignant Breast Cancer and Benign Breast Conditions

scientific article published on 17 May 2016

Circulating giant macrophages as a potential biomarker of solid tumors

scientific article

Circulating tumor cell and cell-free RNA capture and expression analysis identify platelet-associated genes in metastatic lung cancer.

scientific article

Circulating tumor cells (CTCs) in breast cancer: a diagnostic tool for prognosis and molecular analysis ⬇️

scientific article published on December 1, 2012

Circulating tumor cells: evolving evidence and future challenges

scientific article

Circulating tumor cells: silent predictors of metastasis.

scientific article published on 14 August 2017

Cytometric characterization of circulating tumor cells captured by microfiltration and their correlation to the CellSearch(®) CTC test

scientific article published on 16 December 2014

Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer

scientific article published on 31 July 2015

EZH2 knockdown suppresses the growth and invasion of human inflammatory breast cancer cells

scientific article published on 27 September 2013

Effective antibody therapy induces host-protective antitumor immunity that is augmented by TLR4 agonist treatment ⬇️

scientific article published on August 13, 2011

Fibroblast activation protein and its relationship to clinical outcome in pancreatic adenocarcinoma

scientific article published in August 2008

Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936.

scientific article published on February 2004

Induction of adaptive Anti-HER2/neu immune responses in a Phase 1B/2 trial of 2B1 bispecific murine monoclonal antibody in metastatic breast cancer (E3194): a trial coordinated by the Eastern Cooperative Oncology Group

scientific article published on 01 May 2007

Isolation and characterization of circulating tumor cells in patients with metastatic colorectal cancer

scientific article

Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence.

scientific article published on 31 January 2017

Mitosis in circulating tumor cells stratifies highly aggressive breast carcinomas

scientific article published on 4 May 2016

Modified skin-window technique in cynomolgus macaques (Macaca fasicularis) for assessing neutrophil extravasation ⬇️

scientific article published on July 1, 2010

Multi-Phenotypic subtyping of circulating tumor cells using sequential fluorescent quenching and restaining

scientific article published on 20 September 2016

Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer.

scientific article

Mutational studies on single circulating tumor cells isolated from the blood of inflammatory breast cancer patients

scientific article

Naptumomab estafenatox: a new immunoconjugate

scientific article published on February 2010

Phase I and pharmacokinetic study of the farnesyltransferase inhibitor R115777 in combination with irinotecan in patients with advanced cancer

scientific article published on 3 February 2004

Phase I dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced non-small-cell lung cancer

scientific article

Phase II and coagulation cascade biomarker study of bevacizumab with or without docetaxel in patients with previously treated metastatic pancreatic adenocarcinoma

scientific article

Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma

scientific article

Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study

scientific article

Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a Gynecologic Oncology Group study.

scientific article published on 12 July 2011

Precision Microfilters as an all in one System for Multiplex Analysis of Circulating Tumor Cells

scientific article published on 11 January 2016

Presence of anaplastic lymphoma kinase in inflammatory breast cancer

scientific article published on October 2013

Prognostic Significance of MUC-1 in Circulating Tumor Cells in Patients With Metastatic Pancreatic Adenocarcinoma

scientific article published on 10 March 2016

Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model

scientific article published in August 2002

Regulation of antibody-dependent cellular cytotoxicity by IgG intrinsic and apparent affinity for target antigen

scientific article published on September 2007

Response of an ERBB2-mutated inflammatory breast carcinoma to human epidermal growth factor receptor 2-targeted therapy

scientific article published on 10 February 2014

TP53 mutations detected in circulating tumor cells present in the blood of metastatic triple negative breast cancer patients

scientific article

List of works by R Katherine Alpaugh

A Phase I/II study of suberoylanilide hydroxamic acid (SAHA) in combination with trastuzumab (Herceptin) in patients with advanced metastatic and/or local chest wall recurrent HER2-amplified breast cancer: a trial of the ECOG-ACRIN Cancer Research G

A phase I-II study of the histone deacetylase inhibitor vorinostat plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in locally advanced breast cancer

A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: a Gynecologic Oncology Group study

A phase II trial of the proteasome inhibitor bortezomib in patients with advanced biliary tract cancers

An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression.

Biodistribution and Radiation Dosimetry of the Integrin Marker 18F-RGD-K5 Determined from Whole-Body PET/CT in Monkeys and Humans ⬇️

Biodistribution and radiation dosimetry of the hypoxia marker 18F–HX4 in monkeys and humans determined by using whole-body PET/CT ⬇️

Blocking NK cell inhibitory self-recognition promotes antibody-dependent cellular cytotoxicity in a model of anti-lymphoma therapy

Circulating Cancer-Associated Macrophage-Like Cells Differentiate Malignant Breast Cancer and Benign Breast Conditions

Circulating giant macrophages as a potential biomarker of solid tumors

Circulating tumor cell and cell-free RNA capture and expression analysis identify platelet-associated genes in metastatic lung cancer.

Circulating tumor cells (CTCs) in breast cancer: a diagnostic tool for prognosis and molecular analysis ⬇️

Circulating tumor cells: evolving evidence and future challenges

Circulating tumor cells: silent predictors of metastasis.

Cytometric characterization of circulating tumor cells captured by microfiltration and their correlation to the CellSearch(®) CTC test

Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer

EZH2 knockdown suppresses the growth and invasion of human inflammatory breast cancer cells

Effective antibody therapy induces host-protective antitumor immunity that is augmented by TLR4 agonist treatment ⬇️

Fibroblast activation protein and its relationship to clinical outcome in pancreatic adenocarcinoma

Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936.

Induction of adaptive Anti-HER2/neu immune responses in a Phase 1B/2 trial of 2B1 bispecific murine monoclonal antibody in metastatic breast cancer (E3194): a trial coordinated by the Eastern Cooperative Oncology Group

Isolation and characterization of circulating tumor cells in patients with metastatic colorectal cancer

Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence.

Mitosis in circulating tumor cells stratifies highly aggressive breast carcinomas

Modified skin-window technique in cynomolgus macaques (Macaca fasicularis) for assessing neutrophil extravasation ⬇️

Multi-Phenotypic subtyping of circulating tumor cells using sequential fluorescent quenching and restaining

Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer.

Mutational studies on single circulating tumor cells isolated from the blood of inflammatory breast cancer patients

Naptumomab estafenatox: a new immunoconjugate

Phase I and pharmacokinetic study of the farnesyltransferase inhibitor R115777 in combination with irinotecan in patients with advanced cancer

Phase I dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced non-small-cell lung cancer

Phase II and coagulation cascade biomarker study of bevacizumab with or without docetaxel in patients with previously treated metastatic pancreatic adenocarcinoma

Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma

Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study

Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a Gynecologic Oncology Group study.

Precision Microfilters as an all in one System for Multiplex Analysis of Circulating Tumor Cells

Presence of anaplastic lymphoma kinase in inflammatory breast cancer

Prognostic Significance of MUC-1 in Circulating Tumor Cells in Patients With Metastatic Pancreatic Adenocarcinoma

Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model

Regulation of antibody-dependent cellular cytotoxicity by IgG intrinsic and apparent affinity for target antigen

Response of an ERBB2-mutated inflammatory breast carcinoma to human epidermal growth factor receptor 2-targeted therapy

TP53 mutations detected in circulating tumor cells present in the blood of metastatic triple negative breast cancer patients