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List of works by Dianne Cox

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.

scientific article

A Rab11-containing rapidly recycling compartment in macrophages that promotes phagocytosis

scientific article

A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages

scientific article published on November 2005

A mix-and-measure assay for determining the activation status of endogenous Cdc42 in cytokine-stimulated macrophage cell lysates

scientific article

A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging

scientific article

A novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism

scientific article

A regulatory role for Src homology 2 domain-containing inositol 5'-phosphatase (SHIP) in phagocytosis mediated by Fc gamma receptors and complement receptor 3 (alpha(M)beta(2); CD11b/CD18)

scientific article

A requirement for ARF6 in Fcgamma receptor-mediated phagocytosis in macrophages

scientific article published on August 1998

A requirement for phosphatidylinositol 3-kinase in pseudopod extension

scientific article published on January 1999

An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction

scientific article

Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway.

scientific article

Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP.

scientific article published on 09 September 2009

Characterization of Genetically Encoded FRET Biosensors for Rho-Family GTPases.

scientific article published in January 2018

Chemotactic responses by macrophages to a directional source of a cytokine delivered by a micropipette

scientific article published in January 2014

Contribution of CXCL12 secretion to invasion of breast cancer cells.

scientific article

Exosomes and nanotubes: Control of immune cell communication

scientific article published on 15 December 2015

Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction

scientific article published on 24 February 2004

Generation of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeleton

scientific article

Genetic deletion of ABP-120 alters the three-dimensional organization of actin filaments in Dictyostelium pseudopods

scientific article

High-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors

scientific article published on 13 February 2009

Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro

scientific article

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration

scientific article

Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop

scientific article published on June 2005

Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.

scientific article

Myosin X is a downstream effector of PI(3)K during phagocytosis

scientific journal article

N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis

scientific article

Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes

scientific article published on 17 September 2010

Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.

scientific article

Phagocytic signaling strategies: Fc(gamma)receptor-mediated phagocytosis as a model system

scientific article

Phagocytosis inhibits F-actin-enriched membrane protrusions stimulated by fractalkine (CX3CL1) and colony-stimulating factor 1.

scientific article

Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion

scientific article

Rac1 and Cdc42 are required for phagocytosis, but not NF-kappaB-dependent gene expression, in macrophages challenged with Pseudomonas aeruginosa

article

Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants

scientific article published on May 1996

Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages

scientific article published on 6 October 2009

Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis

scientific article published on 26 February 2011

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

scientific article

Short-chain fatty acids inhibit invasive human colon cancer by modulating uPA, TIMP-1, TIMP-2, mutant p53, Bcl-2, Bax, p21 and PCNA protein expression in an in vitro cell culture model.

scientific article

Signaling networks regulating leukocyte podosome dynamics and function

scientific article published on 20 February 2011

Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine).

scientific article published on September 2005

Syk regulates multiple signaling pathways leading to CX3CL1 chemotaxis in macrophages

scientific article

Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly

scientific article published on July 1996

Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences.

scientific article

T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse

scientific article

Targeted disruption of the ABP-120 gene leads to cells with altered motility

scientific article published on February 1992

The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12.

scientific article

The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis

scientific article published on 17 August 2017

The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusions

scientific article

The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42.

scientific article published on 26 June 2009

The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association

scientific article

The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts

scientific article

The non-redundant role of N-WASP in podosome-mediated matrix degradation in macrophages

scientific article published on 21 August 2010

Tunneling nanotubes, a novel mode of tumor cell-macrophage communication in tumor cell invasion

scientific article published on 11 February 2019

Two-dimensional motility of a macrophage cell line on microcontact-printed fibronectin

scientific article published on September 2014

Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function

scientific article published on 30 January 2014

Using Fluorescence Resonance Energy Transfer-Based Biosensors to Probe Rho GTPase Activation During Phagocytosis

scientific article published in January 2017

Visualization of actin polymerization in invasive structures of macrophages and carcinoma cells using photoconvertible β-actin-Dendra2 fusion proteins

scientific article

Western analysis of intracellular interleukin-8 in human mononuclear leukocytes

scientific article published on January 2014

Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis

scientific article published on August 2013