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List of works by Rafael Gómez

Amine and ammonium functionalization of chloromethylsilane-ended dendrimers. Antimicrobial activity studies.

scientific article

Amphiphilic carbosilane dendrons as a novel synthetic platform toward micelle formation.

scientific article published on 22 August 2017

Amphiphilic cationic carbosilane-PEG dendrimers: synthesis and applications in gene therapy.

scientific article

An NMR and molecular modeling study of carbosilane-based dendrimers functionalized with phenolic groups or titanium complexes at the periphery

scientific article published on 01 February 2005

Analysis of interaction between dendriplexes and bovine serum albumin

scientific article published on 21 June 2007

Anionic Carbosilane Dendrimers Destabilize the GP120-CD4 Complex Blocking HIV-1 Entry and Cell to Cell Fusion

scientific article published on 23 March 2018

Anionic sulfonated and carboxylated PPI dendrimers with the EDA core: synthesis and characterization of selective metal complexing agents

scientific article published on 01 April 2013

Anti-Human Immunodeficiency Virus Activity of Thiol-Ene Carbosilane Dendrimers and Their Potential Development as a Topical Microbicide

scientific article published on October 2015

Antibacterial Effect of Carbosilane Metallodendrimers in Planktonic Cells of Gram-Positive and Gram-Negative Bacteria and Staphylococcus aureus Biofilm

scientific article published on 23 August 2019

Antibacterial and antifungal properties of dendronized silver and gold nanoparticles with cationic carbosilane dendrons.

scientific article

Anticancer Activity of Dendriplexes against Advanced Prostate Cancer from Protumoral Peptides and Cationic Carbosilane Dendrimers

scientific article published on 05 February 2019

Antioxidant and Antibacterial Properties of Carbosilane Dendrimers Functionalized with Polyphenolic Moieties

scientific article published on 24 July 2020

Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1.

scientific article published on 5 April 2016

Arylimido niobium(V) complexes: mononuclear and dendritic derivatives

scholarly article by José M Benito et al published December 2002 in Journal of Organometallic Chemistry

Bifunctional Chelating Agents Based on Ionic Carbosilane Dendrons with DO3A at the Focal Point and Their Complexation Behavior with Copper(II)

scientific article published on 11 September 2015

Binding properties of water-soluble carbosilane dendrimers.

scientific article published on 30 August 2008

CATIONIC CARBOSILANE DENDRITC SYSTEMS AS PROMISING ANTI-AMYLOID AGENTS IN TYPE 2 DIABETES

scientific article published on 07 April 2020

Carbosilane Dendron-Peptide Nanoconjugates as Antimicrobial Agents

scientific article published on 30 April 2019

Carbosilane dendrimer 2G-NN16 represses Tc17 differentiation in primary T CD8+ lymphocytes.

scientific article published on 16 November 2011

Carbosilane dendrimers NN8 and NN16 form a stable complex with siGAG1

scientific article published on 16 November 2010

Carbosilane dendrimers are a non-viral delivery system for antisense oligonucleotides: characterization of dendriplexes

scientific article

Carbosilane dendrimers as gene delivery agents for the treatment of HIV infection.

scientific article published on 8 April 2014

Carbosilane dendrimers containing peripheral cyclopentadienyl niobium- and tantalum-imido complexes

scholarly article by José M. Benito et al published August 2006 in Journal of Organometallic Chemistry

Carbosilane dendrimers peripherally functionalized with dansyl fluorescence tags and their cellular internalization studies

article published in 2009

Carbosilane dendrimers to transfect human astrocytes with small interfering RNA targeting human immunodeficiency virus

scientific article published on October 2010

Carbosilane metallodendrimers based on copper (II) complexes: Synthesis, EPR characterization and anticancer activity

scientific article published on 27 September 2017

Cationic species derived from the η1-amidosilyl-η5-cyclopentadienyl dimethyl titanium complex. Crystal structure of [Ti{η5-C5H4SiMe2[η1-N(2,6-Me2C6H3)]}{CH2B(C6F5)2}(C6F5)]

scholarly article by Rafael Gómez et al published October 1999 in Journal of Organometallic Chemistry

Changes in gene expression pattern of human primary macrophages induced by carbosilane dendrimer 2G-NN16.

scientific article

Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes.

scientific article

Copper (II) Metallodendrimers Combined with Pro-Apoptotic siRNAs as a Promising Strategy Against Breast Cancer Cells

scientific article published on 02 August 2020

Dendrimer-protein interactions versus dendrimer-based nanomedicine

scientific article

Dendrimers as nonviral vectors in dendritic cell-based immunotherapies against human immunodeficiency virus: steps toward their clinical evaluation.

scientific article published on December 2014

Dendrimers as topical microbicides with activity against HIV

article

Dendrimers in RNAi Delivery

Dendronization of gold nanoparticles decreases their effect on human alpha-1-microglobulin.

scientific article published on 2 November 2017

Dendronized Anionic Gold Nanoparticles: Synthesis, Characterization, and Antiviral Activity

scientific article

Dendronized PLGA nanoparticles with anionic carbosilane dendrons as antiviral agents against HIV infection

article

Dendronized magnetic nanoparticles for HIV-1 capture and rapid diagnostic

scientific article published on 23 May 2019

Development of sulphated and naphthylsulphonated carbosilane dendrimers as topical microbicides to prevent HIV-1 sexual transmission.

scientific article published on May 2013

Development of water-soluble polyanionic carbosilane dendrimers as novel and highly potent topical anti-HIV-2 microbicides.

scientific article

Dinuclear titanium metallocene-type complexes with the bridging (dimethylsilylidene)bis(cyclopentadienyl) ligand. X-ray structures of [{TiCl2(.eta.5-C5Me5)}2{.mu.-.eta.5-.eta.5-(C5H4)2SiMe2}] and of [{TiCl(.eta.5-C5H5)}2(.mu.-O){.mu.-.eta.5-.eta.5-(C

scholarly article by Tomas Cuenca et al published August 1993 in Inorganic Chemistry

Effect of PEGylation on the biological properties of cationic carbosilane dendronized gold nanoparticles

scientific article published on 22 November 2019

Effect of Several HIV Antigens Simultaneously Loaded with G2-NN16 Carbosilane Dendrimer in the Cell Uptake and Functionality of Human Dendritic Cells.

scientific article published in December 2016

Efficacy of HIV antiviral polyanionic carbosilane dendrimer G2-S16 in the presence of semen

scientific article published on 30 May 2016

Efficacy of carbosilane dendrimers with an antiretroviral combination against HIV-1 in the presence of semen-derived enhancer of viral infection

scientific article published on 31 May 2017

Electroanalytical study of five carbosilane dendrimers at the interface between two immiscible electrolyte solutions

scientific article published on 06 January 2021

Enhanced activity of carbosilane dendrimers against HIV when combined with reverse transcriptase inhibitor drugs: searching for more potent microbicides

scientific article

Erratum: Changes in Gene Expression Pattern of Human Primary Macrophages Induced by Carbosilane Dendrimer 2G-NN16

article

Evaluation of pH-dependent amphiphilic carbosilane dendrons in micelle formation, drug loading and HIV-1 infection

scientific article published on 18 November 2020

Evaluation of the activity of new cationic carbosilane dendrimers on trophozoites and cysts of Acanthamoeba polyphaga

scientific article published on 31 October 2014

Exploring the Interactions of Ruthenium (II) Carbosilane Metallodendrimers and Precursors with Model Cell Membranes through a Dual Spin-Label Spin-Probe Technique Using EPR

scientific article published on 27 September 2019

Factors affecting interactions between sulphonate-terminated dendrimers and proteins: A three case study

scientific article published on 11 October 2016

Fluorescein labelled cationic carbosilane dendritic systems for biological studies

article

Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials

scientific article published on 21 September 2017

Functionalization of silica with amine and ammonium alkyl chains, dendrons and dendrimers: Synthesis and antibacterial properties

scientific article published on 20 December 2019

G2-S16 dendrimer as a candidate for a microbicide to prevent HIV-1 infection in women

scientific article published on 4 July 2017

Gene therapy in HIV-infected cells to decrease viral impact by using an alternative delivery method

scientific article published on June 2010

Generation effects on the microstructure and product distribution in ethylene polymerization promoted by dendritic nickel catalysts.

scientific article

Globular carbosilane dendrimers with mannose groups at the periphery: synthesis, characterization and toxicity in dendritic cells

article

Gold nanoparticles stabilized by cationic carbosilane dendrons: synthesis and biological properties

scientific article

HIV-1 antiviral behavior of anionic PPI metallo-dendrimers with EDA core

scientific article published on 18 May 2015

Heterofunctional ruthenium(II) carbosilane dendrons, a new class of dendritic molecules to fight against prostate cancer

scientific article published on 18 August 2020

Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity

scientific article

Hyperbranched polymers versus dendrimers containing a carbosilane framework and terminal ammonium groups as antimicrobial agents.

scientific article

Improved Efficiency of Ibuprofen by Cationic Carbosilane Dendritic Conjugates.

scientific article published on 17 August 2016

In vivo delivery of siRNA to the brain by carbosilane dendrimer.

scientific article

Insight into the antitumor activity of carbosilane Cu(ii)-metallodendrimers through their interaction with biological membrane models

scientific article published on 04 July 2019

Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells Cultured in 3D Spheroids

scientific article published on 19 May 2022

Mesoporous Silica Nanoparticles Decorated with Carbosilane Dendrons as New Non-viral Oligonucleotide Delivery Carriers

scientific article published on 11 September 2015

Monocyclopentadienyl-type titanium complexes with the [.eta.5-.eta.5-(C5H4)2SiMe2]2- ligand. X-ray crystal structure of [(TiCl)2(.mu.2-O){.mu.2-.eta.5-.eta.5-(C5H4)2SiMe2}]2(.mu.2-O)2. The first example of a nonplanar titanium oxide ["Ti4O4"] core

scholarly article by Santiago Ciruelos et al published March 1993 in Organometallics

Monocyclopentadienyl-type titanium complexes with the [.eta.5-.eta.5-(C5H4)2SiMe2]2-ligand. X-ray crystal structure of [(TiCl)2(.mu.2-O){.mu.2-.eta.5-.eta.5-(C5H4)2SiMe2}]2(.mu.2-O)2. The first example of a nonpolar titanium oxide ["Ti4O4"] core. [Er

scholarly article by Santiago Ciruelox et al published August 1993 in Organometallics

Mononuclear and Dendritic Nickel(II) Complexes ContainingN,N‘-Iminopyridine Chelating Ligands: Generation Effects on the Catalytic Oligomerization and Polymerization of Ethylene†

Nanosystems as Vehicles for the Delivery of Antimicrobial Peptides (AMPs)

scientific article published on 02 September 2019

Nanotech-derived topical microbicides for HIV prevention: the road to clinical development

scientific article

Nanotechnology as a New Therapeutic Approach to Prevent the HIV-Infection of Treg Cells

scientific article published on 19 January 2016

Neutral and Cationic Aluminum and Titanium Complexes Incorporating Sterically Demanding Organosilicon Ligands

scholarly article by Virginia Amo et al published May 2005 in Organometallics

New anionic carbosilane dendrons functionalized with a DO3A ligand at the focal point for the prevention of HIV-1 infection.

scientific article published on 18 August 2017

Novel non-viral gene delivery systems composed of carbosilane dendron functionalized nanoparticles prepared from nano-emulsions as non-viral carriers for antisense oligonucleotides

scientific article

PEGylated AgNP covered with cationic carbosilane dendrons to enhance antibacterial and inhibition of biofilm properties

scientific article published on 05 August 2019

Phenotype and functional analysis of human monocytes-derived dendritic cells loaded with a carbosilane dendrimer.

scientific article

Polyanionic N-donor ligands as chelating agents in transition metal complexes: synthesis, structural characterization and antiviral properties against HIV

article

Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: Recent trends and developments in HIV treatment/therapy.

scientific article published on 31 March 2015

Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture

scientific article published on 22 August 2016

Polycationic carbosilane dendrimer decreases angiogenesis and tumor-associated macrophages in tumor-bearing mice

scholarly article in RSC Advances, vol. 5 no. 126, 2015

Prevention of vaginal and rectal herpes simplex virus type 2 transmission in mice: mechanism of antiviral action.

scientific article published on 19 May 2016

Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16.

scientific article

Proof of concept of a "greener" protein purification/enrichment method based on carboxylate-terminated carbosilane dendrimer-protein interactions

scientific article published on 9 September 2016

Role of cationic carbosilane dendrons and metallic core of functionalized gold nanoparticles in their interaction with human serum albumin

scientific article published on 08 July 2018

Ruthenium dendrimers against acute promyelocytic leukemia: in vitro studies on HL-60 cells

scientific article published on 09 July 2019

Ruthenium dendrimers as carriers for anticancer siRNA.

scientific article published on 12 January 2018

Silver Nanoparticles Surface-Modified with Carbosilane Dendrons as Carriers of Anticancer siRNA ⬇️

scientific article published on 30 June 2020

Silyl and siloxanediyl cyclopentadienyl titanium and zirconium complexes: synthesis and reactivity. X-ray molecular structure of [Zr{η5-C5H4SiMe2(μ-OH)} (μ-Cl)Cl2]2

scholarly article by Santiago Ciruelos et al published January 1998 in Polyhedron

Study of cationic carbosilane dendrimers as potential activating stimuli in macrophages

scholarly article in RSC Advances, vol. 3 no. 45, 2013

Study of non-covalent interactions on dendriplex formation: Influence of hydrophobic, electrostatic and hydrogen bonds interactions.

scientific article published on 8 December 2017

Sulfonate-ended carbosilane dendrimers with a flexible scaffold cause inactivation of HIV-1 virions and gp120 shedding.

scientific article

Synergistic activity of carbosilane dendrimers in combination with maraviroc against HIV in vitro.

scientific article published on August 2013

Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide

scientific article published on 14 October 2013

Synthesis and Characterization of FITC Labelled Ruthenium Dendrimer as a Prospective Anticancer Drug

scientific article published on 25 August 2019

Synthesis and Reactivity of [(Amidosilyl)cyclopentadienyl]titanium and -zirconium Complexes. X-ray Molecular Structure of [Zr{η5:η1-C5H4SiMe2(μ-O)}Cl2{H2N(CHMe)Ph}]2†

scholarly article by Santiago Ciruelos et al published January 1996 in Organometallics

Synthesis and anticancer activity of carbosilane metallodendrimers based on arene ruthenium(ii) complexes

scientific article

Synthesis and characterization of ansa-dimethylsilylbiscyclopentadienyl titanium(II) complexes. Crystal structure of [Ti{Me2Si(C5H4)2}{CN(2,6-Me2C6H3)}2]

scholarly article by Tomás Cuenca et al published July 1993 in Journal of Organometallic Chemistry

Synthesis and fluorescent properties of cationic carbosilane dendrimers containing eugenol linkers for their use in biomedical applications

article

Synthesis and reactivity of new silyl substituted monocyclopentadienyl zirconium complexes. X-ray molecular structure of [Zrη5-C5H4 (SiMe2CH2Ph)(CH2Ph)3]

scholarly article by Gemma Ciruelo et al published December 1997 in Journal of Organometallic Chemistry

Synthesis and1H NMR studies of paramagnetic nickel(ii) complexes containing bis(pyrazolyl)methane ligands with dendritic substituents

scientific article published on 18 July 2006

Synthesis of Aryloxo Cyclopentadienyl Group 4 Metal-Containing Dendrimers

Synthesis of anionic carbosilane dendrimers via “click chemistry” and their antiviral properties against HIV

article

Synthesis of carbosilane dendrons and dendrimers derived from 1,3,5-trihydroxybenzene

article

Synthesis of cationic carbosilane dendrimers via click chemistry and their use as effective carriers for DNA transfection into cancerous cells.

scientific article

Synthesis of new anionic carbosilane dendrimers via thiol-ene chemistry and their antiviral behaviour

scientific article published on 14 April 2014

Synthesis of polymetallic Group 4 complexes bridged by benzenediolate and triolate ligands. X-ray crystal structure of [{Ti(C5Me5)Cl2}2{μ-1,4-O(2,3-C6H2Me2)O}]

Synthesis, characterization and antibacterial behavior of water-soluble carbosilane dendrons containing ferrocene at the focal point.

scientific article

Synthesis, structure and molecular modelling of anionic carbosilane dendrimers.

scientific article

The inhibition of Th17 immune response in vitro and in vivo by the carbosilane dendrimer 2G-NN16

article

Transition-Metal Complexes Based on a Sulfonate-Containing N-Donor Ligand and Their Use as HIV Antiviral Agents

article

Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission

scientific article published on January 2015

Tris(pyrazolyl)methane Ligands: Syntheses and Structures of Monometallic and Metallodendritic Complexes

Ultrastructural Study of Acanthamoeba polyphaga Trophozoites and Cysts Treated In Vitro with Cationic Carbosilane Dendrimers

scientific article published on 18 June 2020

Use of carbosilane dendrimer to switch macrophage polarization for the acquisition of antitumor functions

scientific article published on 01 March 2015

Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins.

scientific article published on 14 May 2007

Water-soluble carbosilane dendrimers: synthesis biocompatibility and complexation with oligonucleotides; evaluation for medical applications

scientific article published on 01 January 2007

Water-stable ammonium-terminated carbosilane dendrimers as efficient antibacterial agents.

scientific article published on 27 August 2009

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