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List of works by Jeroen P Roose

A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.

scientific article published on 27 September 2017

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

scientific article

All Tcf HMG box transcription factors interact with Groucho-related co-repressors

scientific article

Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation

scientific article published on 23 July 2019

Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression

scientific article

Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy.

scientific article

Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases

scientific article published on 19 September 2019

Digital signaling and hysteresis characterize ras activation in lymphoid cells

scientific article

High expression of the HMG box factor sox-13 in arterial walls during embryonic development

scientific article published on 15 January 1998

Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesis

scientific article published on 28 September 2020

Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases.

scientific article

One-way membrane trafficking of SOS in receptor-triggered Ras activation

scientific article

Protocol for Comprehensive Synthetic Lethality Screens

scientific article published on 03 June 2020

Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1

scientific article

T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression

scientific article

The Sox-13 gene: structure, promoter characterization, and chromosomal localization

scientific article

The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization

scientific article

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

scientific article

Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes

scientific article

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

scientific article

mTOR and other effector kinase signals that impact T cell function and activity

scientific article published on 01 September 2019

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