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List of works by Ann W Morgan

Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action ⬇️

scientific article

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF B signalling pathways

article

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response

scientific article published on April 2015

Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for and CD39

article

Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis

article

Cardiovascular risk and rheumatoid arthritis--the next step: differentiating true soluble biomarkers of cardiovascular risk from surrogate measures of inflammation ⬇️

scientific article published on July 13, 2011

Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis

scientific article published on May 2015

Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

scientific article published on February 2015

Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort

scientific article

Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis

scientific article published on 28 February 2012

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study S

scientific article published on 7 October 2012

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

scientific article

Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels. ⬇️

scientific article published on 25 August 2016

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis ⬇️

scientific article published on 27 January 2016

Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease

scientific article published on 20 August 2009

Does the shared epitope genotype influence either the susceptibility to or the phenotype of corneal melting? ⬇️

scientific article published on August 1, 2001

Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study

scientific article published on 03 December 2020

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment

scientific article published on 17 May 2013

Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris

scientific article

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

scientific article

Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients

scientific article

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

scientific article

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci

scientific article

High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort ⬇️

scientific article published on 31 May 2016

Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort

scientific article

Impact of psychological factors on subjective disease activity assessments in patients with severe rheumatoid arthritis

scientific article

In situ macromolecular crystallography using microbeams

scientific article published on 17 April 2012

Informed conditioning on clinical covariates increases power in case-control association studies

scientific article published on 8 November 2012

Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples

scientific article

Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci

scientific article published on 09 September 2009

Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients

scientific article published in April 2009

Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment

scientific article

Latent class trajectory modelling of 2-components-DAS28 identifies multiple rheumatoid arthritis phenotypes of response to biologic disease modifying anti-rheumatic drugs

scientific article published on 31 May 2020

Outrunning free radicals in room-temperature macromolecular crystallography

scientific article published on 15 June 2012

Pharmacogenetics of TNF inhibitor response in rheumatoid arthritis utilizing the two-component disease activity score

scientific article published on 30 October 2020

Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response

scientific article published in May 2010

Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort ⬇️

scientific article published on 16 May 2016

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

scientific article published on 22 April 2008

Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort

scientific article

Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study

scientific article published on 18 March 2015

Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy

scientific article published on July 2010

Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

scientific article published on 14 September 2008

Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach

scientific article published on 9 December 2013

The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort ⬇️

scientific article

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