Search filters

List of works by Richard A Engh

Biofocussed chemoprospecting: An efficient approach for drug discovery.

scientific article

Cis/Trans Isomerization in Secondary Amides: Reaction Paths, Nitrogen Inversion, and Relevance to Peptidic Systems.

scientific article published on 15 August 2017

Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization

scientific article published on 25 September 2018

Differential Sensitivity of ERBB2 Kinase Domain Mutations towards Lapatinib

scientific article published on October 28, 2011

Inhibitor binding to mutants of protein kinase A with GGGxxG and GxGxxA glycine-rich loop motifs

scientific article published on 15 November 2020

Lysine 156promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA

scientific article published on August 15, 1997

New enzyme lineages by subdomain shuffling

scientific article published on August 18, 1998

Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

scientific article published on 23 August 2018

Quail cystatin: Isolation and characterisation of a new member of the cystatin family and its hypothetical interaction with cathepsin B

scientific article published on August 4, 1997

Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

scientific article published on December 15, 1997

Structure of malonic acid‐based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data

scientific article published on June 1, 1998

The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro

scientific article published on October 25, 2010

Two SnRK2-Interacting Calcium Sensor Isoforms Negatively Regulate SnRK2 Activity by Different Mechanisms

scientific article published on 07 November 2019

VX680 Binding in Aurora A: π−π Interactions Involving the Conserved Aromatic Amino Acid of the Flexible Glycine-Rich Loop

scientific article published on 09 February 2011

p38α MAP Kinase Dimers with Swapped Activation Segments and a Novel Catalytic Loop Conformation

scientific article published on June 15, 2011