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List of works by David M Weinstock

A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas

scientific article

A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia

scientific article published on 17 March 2022

A targeted mutational landscape of angioimmunoblastic T-cell lymphoma.

scientific article

AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells

scientific article published on 07 November 2019

Activity of the PI3K-δ,γ inhibitor duvelisib in a phase I trial and preclinical models of T-cell lymphoma

scientific article

Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia

scientific article published in July 2015

Allocation of scarce resources after a nuclear detonation: setting the context.

scientific article

Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas

scientific article published on 08 August 2018

Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.

scientific article published on 14 March 2017

Assessing surge capacity for radiation victims with marrow toxicity

scientific article

Assessment of CD52 expression in "double-hit" and "double-expressor" lymphomas: Implications for clinical trial eligibility

scientific article published on 18 July 2018

BCL2 suppresses PARP1 function and nonapoptotic cell death.

scientific article

BCR-ABL promotes the frequency of mutagenic single-strand annealing DNA repair

scientific article published on July 2009

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

scientific article

Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas

scientific article published on 29 November 2018

Bruton tyrosine kinase degradation as a therapeutic strategy for cancer

scientific article published on 13 December 2018

Cancer models: The next best thing

scientific article published on 30 August 2017

Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma

scientific article published on 22 April 2020

Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase

scientific article published on 6 July 2017

Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) Science and the CBRNE Science Medical Operations Science Support Expert (CMOSSE)

scientific article published on 01 December 2019

Clinicogenetic risk modeling in ATL.

scientific article

Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

scientific article published on 6 June 2016

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

scientific article published on 20 May 2015

Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice

scientific article published on 21 November 2017

Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.

scientific article published on 13 June 2017

DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance

scientific article published on 01 November 2019

Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2 ⬇️

scientific article published on August 20, 2012

Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles

scientific article published on 20 August 2018

First global consensus for evidence-based management of the hematopoietic syndrome resulting from exposure to ionizing radiation

scientific article published on 10 October 2011

Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas.

scientific article published on 12 June 2017

Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia

scientific article

Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry

scientific article

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition ⬇️

scientific article published on January 23, 2012

Genomic Analyses Identify Recurrent Alterations in Immune Evasion Genes in Diffuse Large B-Cell Lymphoma, Leg Type

scientific article published on 30 May 2018

Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions

scientific article published on 21 January 2020

HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma

scientific article published on 14 October 2016

Health Care System Planning for and Response to a Nuclear Detonation ⬇️

scientific article published on March 1, 2011

Identification of Circulating Serum Multi-MicroRNA Signatures in Human DLBCL Models

scientific article published on 20 November 2019

Inhibition of USP10 induces degradation of oncogenic FLT3.

scientific article

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome–like acute B-cell lymphoblastic leukemia

scientific article published on 17 January 2018

Literature review and global consensus on management of acute radiation syndrome affecting nonhematopoietic organ systems

scientific article published on 10 October 2011

Low-cost transcriptional diagnostic to accurately categorize lymphomas in low- and middle-income countries

scientific article published on 01 May 2021

Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

scientific article published on 30 April 2019

Medical Response to a Nuclear Detonation: Creating a Playbook for State and Local Planners and Responders ⬇️

scientific article published on March 1, 2011

Medical management of radiation victims in the United States

scientific article published on June 2010

Medical planning and response for a nuclear detonation: a practical guide

scientific article

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance

scientific article

Next-Generation cDNA Screening for Oncogene and Resistance Phenotypes ⬇️

scientific article published on November 7, 2012

Next-generation characterization of the Cancer Cell Line Encyclopedia

scientific article published on 08 May 2019

PARP1 is required for chromosomal translocations.

scientific article published on 8 April 2013

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.

scientific article

PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

scientific article published in November 2017

Parp3 promotes long-range end joining in murine cells

article published in the Proceedings of the National Academy of Sciences of the United States of America

Pediatric-type nodal follicular lymphoma: a biologically distinct lymphoma with frequent MAPK pathway mutations

scientific article published on 20 June 2016

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

scientific article

Planning and Response to Radiation Exposures ⬇️

scientific article published on June 15, 2011

Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer.

scientific article published on 6 January 2016

Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair

scientific article published on 19 October 2020

Public health and medical preparedness for a nuclear detonation: the nuclear incident medical enterprise.

scientific article

Radiation Disasters: Role of the BMT Team ⬇️

scientific article published on January 1, 2012

Radiation Injury After a Nuclear Detonation: Medical Consequences and the Need for Scarce Resources Allocation ⬇️

scientific article published on March 1, 2011

Radiation Injury Treatment Network (RITN): Healthcare professionals preparing for a mass casualty radiological or nuclear incident ⬇️

scientific article published on February 28, 2011

Radiologic and nuclear events: contingency planning for hematologists/oncologists

scientific article

Rapid identification of BCR/ABL1-like acute lymphoblastic leukaemia patients using a predictive statistical model based on quantitative real time-polymerase chain reaction: clinical, prognostic and therapeutic implications.

scientific article published on 19 April 2018

Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

scientific article published on 18 November 2020

Repair at Single Targeted DNA Double-Strand Breaks in Pluripotent and Differentiated Human Cells ⬇️

scientific article published on May 25, 2011

Resource allocation after a nuclear detonation incident: unaltered standards of ethical decision making.

scientific article

Response: Radiologic and nuclear events

scientific article published on 01 June 2008

RhoA G17V is sufficient to induce autoimmunity and promotes T-cell lymphomagenesis in mice

scientific article published on 16 May 2018

Scarce resources for nuclear detonation: project overview and challenges

scientific article

Stem cells, multiorgan failure in radiation emergency medical preparedness: a U.S./European Consultation Workshop

scientific article

Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia

scientific article published on 9 November 2016

TFH lymphomas: the times they aza-changin'?

scientific article published on 01 October 2019

TSLP Signaling Network Revealed by SILAC-Based Phosphoproteomics ⬇️

scientific article published on February 16, 2012

Targetable subsets of non-Hodgkin lymphoma in Malawi define therapeutic opportunities

scientific article published on 22 November 2016

Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models.

scientific article published on 22 May 2018

Targeted inhibition of CD47-SIRPα requires Fc-FcγR interactions to maximize activity in T-cell lymphomas

scientific article published on 01 October 2019

Targeting EZH2 for the treatment of hepatosplenic T-cell lymphoma

scientific article published on 01 April 2020

Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia

scientific article

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on April 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on 11 July 2016

Triage and Treatment Tools for Use in a Scarce Resources-Crisis Standards of Care Setting After a Nuclear Detonation ⬇️

scientific article published on March 1, 2011

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

scientific article

Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias

scientific article

Using the Model of Resource and Time-Based Triage (MORTT) to Guide Scarce Resource Allocation in the Aftermath of a Nuclear Detonation ⬇️

scientific article published on March 1, 2011

t(X;14)(p22;q32)/t(Y;14)(p11;q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not ⬇️

scientific article published on September 16, 2010

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