List of works - Franz Bracher

7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes

scientific article

A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine

scientific article published on 24 February 2020

Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines - a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline

scientific article published on 11 January 2018

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

scientific article

Characterization of two new degradation products of atorvastatin calcium formed upon treatment with strong acids

scientific article published on 02 September 2019

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol

scientific article published on 26 June 2019

Determination of multi pesticide residues in leaf and needle samples using a modified QuEChERS approach and gas chromatography-tandem mass spectrometry

scientific article published on 05 February 2021

Discovery of a selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerases 14.

scientific article published on 9 October 2017

Functionalization of 4-bromobenzo[c][2,7]naphthyridine via regioselective direct ring metalation. A novel approach to analogues of pyridoacridine alkaloids

scientific article published on 26 September 2019

How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine

scientific article published on 16 December 2020

Inhibition of Phytosterol Biosynthesis by Azasterols

scientific article published on 02 March 2020

Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution

scientific article published on 23 September 2019

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

scientific article published on 14 January 2022

Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells

scientific article published on 21 March 2022

Pharmacokinetic Enhancers (Boosters)-Escort for Drugs against Degrading Enzymes and Beyond

scientific article published on 27 September 2018

Racemic total synthesis and evaluation of the biological activities of the isoquinoline-benzylisoquinoline alkaloid muraricine

scientific article published on 25 May 2020

Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

scientific article

Sterol Composition of Clinically Relevant Mucorales and Changes Resulting from Posaconazole Treatment

scientific article published on 19 May 2018

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

scientific article published on 01 February 2019

The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors

scientific article published on 13 August 2019

List of works by Franz Bracher

7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes

A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine

Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines - a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

Characterization of two new degradation products of atorvastatin calcium formed upon treatment with strong acids

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol

Determination of multi pesticide residues in leaf and needle samples using a modified QuEChERS approach and gas chromatography-tandem mass spectrometry

Discovery of a selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerases 14.

Functionalization of 4-bromobenzo[c][2,7]naphthyridine via regioselective direct ring metalation. A novel approach to analogues of pyridoacridine alkaloids

How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine

Inhibition of Phytosterol Biosynthesis by Azasterols

Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells

Pharmacokinetic Enhancers (Boosters)-Escort for Drugs against Degrading Enzymes and Beyond

Racemic total synthesis and evaluation of the biological activities of the isoquinoline-benzylisoquinoline alkaloid muraricine

Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

Sterol Composition of Clinically Relevant Mucorales and Changes Resulting from Posaconazole Treatment

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors