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List of works by Wolfgang A Linke

A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues

scientific article published on 28 April 2020

A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart

scientific article published on 08 February 2019

A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance

scientific article published on 01 August 2018

Actin-titin interaction in cardiac myofibrils: probing a physiological role

scientific article published on August 1, 1997

Alteration of the Beta-Adrenergic Signaling Pathway in Human Heart Failure

scientific article published on October 1, 2012

Alterations in Titin Properties and Myocardial Fibrosis Correlate With Clinical Phenotypes in Hemodynamic Subgroups of Severe Aortic Stenosis

scientific article published on 25 June 2018

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

Basis of passive tension and stiffness in isolated rabbit myofibrils

scientific article published on 01 July 1997

Cardioprotection and lifespan extension by the natural polyamine spermidine.

scientific article

Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness

scientific article published on January 1, 2003

Graded titin cleavage progressively reduces tension and uncovers the source of A-band stability in contracting muscle

scientific article published on 24 December 2020

HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

scientific article

Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin

scientific article published on 08 September 2020

Myocardial Structure and Function Differ in Systolic and Diastolic Heart Failure

scientific article published on 17 April 2006

Nature of PEVK-titin elasticity in skeletal muscle

scientific article published on July 7, 1998

Overexpression of human BAG3<sup>P209L</sup> in mice causes restrictive cardiomyopathy

scientific article published on 11 June 2021

Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling

scientific article published on 25 March 2009

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.

scientific article published on 17 January 2018

Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx)

scientific article published on 14 September 2020

S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding

scientific article

Sildenafil and B-Type Natriuretic Peptide Acutely Phosphorylate Titin and Improve Diastolic Distensibility In Vivo

scientific article published on December 5, 2011

Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning

scientific article

Striational autoantibodies in myasthenia gravis patients recognize I-band titin epitopes

scientific article published on 01 January 1998

The Giant Protein Titin: A Regulatory Node That Integrates Myocyte Signaling Pathways

scientific article published on January 21, 2011

The Translational Landscape of the Human Heart

scientific article published on 30 May 2019

Titin-truncating variants affect heart function in disease cohorts and the general population.

scientific article

Troponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients

scientific article published on 14 January 2020