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List of works by Gencheng Han

Active tolerance induction and prevention of autoimmune diabetes by immunogene therapy using recombinant adenoassociated virus expressing glutamic acid decarboxylase 65 peptide GAD(500-585).

scientific article

Alterations of T helper lymphocyte subpopulations in sepsis, severe sepsis, and septic shock: a prospective observational study

scientific article published on June 2015

An epithelial-to-mesenchymal transition-inducing potential of granulocyte macrophage colony-stimulating factor in colon cancer.

scientific article published on 15 August 2017

B cells regulate thymic CD8+T cell differentiation in lupus-prone mice.

scientific article published on 5 July 2017

BAFF maintains T-cell survival by inducing OPN expression in B cells

scientific article published on 28 September 2013

Blockade of B-cell activating factor with TACI-IgG effectively reduced Th1 and Th17 cells but not memory T cells in experimental allergic encephalomyelitis mice

scientific article

Blockade of complement activation product C5a activity using specific antibody attenuates intestinal damage in trinitrobenzene sulfonic acid induced model of colitis ⬇️

scientific article published on November 22, 2010

C5a regulates IL-12+ DC migration to induce pathogenic Th1 and Th17 cells in sepsis

scientific article

CD19 regulates ADAM28-mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells.

scientific article published on 14 July 2017

CD8+ regulatory T cells are responsible for GAD-IgG gene-transferred tolerance induction in NOD mice

scientific article published on 20 June 2008

Characterization of IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in experimental autoimmune uveitis

scientific article published on September 2007

Complement C5a regulates IL-17 by affecting the crosstalk between DC and gammadelta T cells in CLP-induced sepsis

scientific article published in April 2010

Critical role for thymic CD19+CD5+CD1dhiIL-10+ regulatory B cells in immune homeostasis

scientific article

Dysregulated Tim-3 expression and its correlation with imbalanced CD4 helper T cell function in ulcerative colitis.

scientific article

Enhanced Expression of T-Cell Immunoglobulin and Mucin Domain Protein 3 in Endothelial Cells Facilitates Intracellular Killing of Rickettsia heilongjiangensis

scientific article published on 23 September 2015

Foxd3 suppresses interleukin-10 expression in B cells

scientific article published on 20 December 2016

Functional identification of the stable transfection C5aR cell line Molt-4.

scientific article published on December 2007

GM-CSF facilitates the development of inflammation-associated colorectal carcinoma

scientific article

Glutamic acid decarboxylase-derived epitopes with specific domains expand CD4(+)CD25(+) regulatory T cells

scientific article

IL-15-secreting γδT cells induce memory T cells in experimental allergic encephalomyelitis (EAE) mice

scientific article published on 18 May 2015

IL-17A signaling in colonic epithelial cells inhibits pro-inflammatory cytokine production by enhancing the activity of ERK and PI3K.

scientific article

Identification of conformational core epitope Lys⁶⁸ in C5a based on the 3-D modeling complex C5a and its functional antibody F20

scientific article published on 06 May 2011

Identify the key amino acid of BAFF binding with TACI.

scientific article published on 14 June 2013

Induction of active tolerance and involvement of CD1d-restricted natural killer T cells in anti-CD3 F(ab')2 treatment-reversed new-onset diabetes in nonobese diabetic mice

scientific article published on 18 March 2008

Interleukin-17-producing gammadelta+ T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-beta

scientific article published on 4 August 2009

Involvement of T cell Ig Mucin-3 (Tim-3) in the negative regulation of inflammatory bowel disease

scientific article published on 13 November 2009

MAE4, an eLtaS monoclonal antibody, blocks Staphylococcus aureus virulence

scientific article

Metabotropic glutamate receptor 3 is involved in B-cell-related tumor apoptosis

scientific article published on 15 July 2016

Minimally activated CD8 autoreactive T cells specific for IRBP express a high level of Foxp3 and are functionally suppressive

scientific article published on May 2007

Monoclonal antibody against human Tim-3 enhances antiviral immune response

scientific article published on 04 January 2019

Mouse gammadelta T cells are capable of expressing MHC class II molecules, and of functioning as antigen-presenting cells

scientific article published on October 2008

Natural killer cells modulate overt autoimmunity to homeostasis in nonobese diabetic mice after anti-CD3 F(ab')2 antibody treatment through secreting transforming growth factor-beta

scientific article published on 30 July 2009

Negative regulation of Nod-like receptor protein 3 inflammasome activation by T cell Ig mucin-3 protects against peritonitis.

scientific article

Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice

scientific article

Prognostic Value of Procalcitonin in Adult Patients with Sepsis: A Systematic Review and Meta-Analysis

scientific article published on 15 June 2015

Prolonging survival of corneal transplantation by selective sphingosine-1-phosphate receptor 1 agonist

scientific article

Protective role of tumor necrosis factor (TNF) receptors in chronic intestinal inflammation: TNFR1 ablation boosts systemic inflammatory response

scientific article published on 29 July 2013

Reactivation of uveitogenic T cells by retinal astrocytes derived from experimental autoimmune uveitis-prone B10RIII mice

scientific article published on January 2008

Regulation of IL-8 production by complement-activated product, C5a, in vitro and in vivo during sepsis

scientific article published on 29 June 2010

Spliceosome protein Eftud2 promotes colitis-associated tumorigenesis by modulating inflammatory response of macrophage

scientific article published on 05 July 2019

Suppressor role of rat CD8+CD45RClow T cells in experimental autoimmune uveitis (EAU)

scientific article published on 28 December 2006

T cell Ig mucin-3 promotes homeostasis of sepsis by negatively regulating the TLR response.

scientific article published on 30 January 2013

T cell immunoglobulin and mucin domain protein 3 inhibits glycolysis in RAW 264.7 macrophages through Hexokinase 2

scientific article published on 08 October 2020

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity ⬇️

scientific article published on December 10, 2010

Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2.

scientific article published on 16 February 2017

Tim-3 promotes intestinal homeostasis in DSS colitis by inhibiting M1 polarization of macrophages

scientific article

Tim-3 promotes tumor-promoting M2 macrophage polarization by binding to STAT1 and suppressing the STAT1-miR-155 signaling axis.

scientific article

Tim-3: an activation marker and activation limiter of innate immune cells

scientific article published on 10 December 2013

Tumor-derived GM-CSF promotes inflammatory colon carcinogenesis via stimulating epithelial release of VEGF.

scientific article published on 23 December 2013

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