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List of works by Christoph Hiemke

"Krokodil":revival of an old drug with new problems

scientific article published on 2 April 2012

"There is no dose-response relationship in psychopharmacotherapy" vs "pharmacotherapy in psychiatry is based on ligand-receptor interaction": a unifying hypothesis and the need for plasma concentration based clinical trials

scientific article published on 04 May 2011

123IIBZM SPECT in patients treated with typical and atypical neuroleptics: relationship to drug plasma levels and extrapyramidal side effects ⬇️

scientific article published on September 29, 1997

A common mechanism of action of the selective serotonin reuptake inhibitors citalopram and fluoxetine: reversal of chronic psychosocial stress-induced increase in CRE/CREB-directed gene transcription in transgenic reporter gene mice

scientific article published in February 2010

A comprehensive review of the clinical utility of and a combined analysis of the clozapine/norclozapine ratio in therapeutic drug monitoring for adult patients

scientific article published on 31 May 2019

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model

scientific article

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model.

scientific article published in August 2004

A systematic review and combined analysis of therapeutic drug monitoring studies for long-acting paliperidone

scientific article published on 04 December 2018

A systematic review and combined analysis of therapeutic drug monitoring studies for long-acting risperidone.

scientific article published on 12 July 2017

A systematic review and combined analysis of therapeutic drug monitoring studies for oral paliperidone

scientific article published on 18 June 2018

AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011 ⬇️

scientific article published on September 27, 2011

Abuse liability of flupirtine revisited: implications of spontaneous reports of adverse drug reactions

scientific article

Abuse of methylphenidate in Germany: data from spontaneous reports of adverse drug reactions

scientific article

Acitretin, an enhancer of alpha-secretase expression, crosses the blood-brain barrier and is not eliminated by P-glycoprotein

scientific article published on February 2012

Actions of sex hormones on the brain

scientific article published on May 1, 1992

Altered brain concentrations of citalopram and escitalopram in P-glycoprotein deficient mice after acute and chronic treatment.

scientific article published on 19 February 2013

Amphiphilic Copolymers Shuttle Drugs Across the Blood-Brain Barrier

scientific article published on 13 January 2016

Antidepressant polypharmacy and the potential of pharmacokinetic interactions: Doxepin but not mirtazapine causes clinically relevant changes in venlafaxine metabolism

scientific article published on 13 November 2017

Antipsychotics for treatment of neuropsychiatric disorders in dementia ⬇️

scientific article published on March 1, 2013

Appropriateness of plasma level determinations for lithium and valproate in routine care of psychiatric inpatients with affective disorders

scientific article published on 01 December 2006

Appropriateness of therapeutic drug monitoring for antidepressants in routine psychiatric inpatient care

scientific article

Aripiprazole in pregnancy and lactation: a case report

scientific article published in April 2010

Assessing drug-drug interactions through therapeutic drug monitoring when administering oral second-generation antipsychotics.

scientific article published on 15 February 2016

Assessment of storage and transport stability of new antidepressant and antipsychotic drugs for a nationwide TDM service.

scientific article

Association between citalopram serum levels and clinical improvement of patients with major depression

scientific article published in June 2011

Association between haemorrhages and treatment with selective and non-selective serotonergic antidepressants: Possible implications of quantitative signal detection

scientific article published on 15 July 2015

Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment.

scientific article published on 14 December 2005

Automated Determination of Clozapine and Major Metabolites in Serum and Urine ⬇️

scientific article published on 01 August 1997

Automated analysis of quetiapine and other antipsychotic drugs in human blood by high performance-liquid chromatography with column-switching and spectrophotometric detection

scientific article

Automated determination of amisulpride by liquid chromatography with column switching and spectrophotometric detection

scientific article

Automated determination of clomipramine and its major metabolites in human and rat serum by high-performance liquid chromatography with on-line column-switching ⬇️

scientific article published on June 12, 1998

Automated determination of ziprasidone by HPLC with column switching and spectrophotometric detection

scientific article published in April 2005

Blood Levels to Optimize Antipsychotic Treatment in Clinical Practice: A Joint Consensus Statement of the American Society of Clinical Psychopharmacology and the Therapeutic Drug Monitoring Task Force of the Arbeitsgemeinschaft für Neuropsychopharma

scientific article published on 19 May 2020

Blood-brain barrier penetration of the enantiomers of venlafaxine and its metabolites in mice lacking P-glycoprotein

scientific article published on 13 May 2010

Body mass index (BMI) but not body weight is associated with changes in the metabolism of risperidone; A pharmacokinetics-based hypothesis.

scientific article

Brain and plasma pharmacokinetics of aripiprazole in patients with schizophrenia: an [18F]fallypride PET study

scientific article

Buprenorphine-cannabis interaction in patients undergoing opioid maintenance therapy

scientific article published on 06 January 2020

Cerebrospinal fluid tau protein levels and 18F-fluorodeoxyglucose positron emission tomography in the differential diagnosis of Alzheimer's disease

scientific article published on 15 September 2010

Chronic lithium salt treatment reduces CRE/CREB-directed gene transcription and reverses its upregulation by chronic psychosocial stress in transgenic reporter gene mice

scientific article published on 28 November 2007

Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus.

scientific article

Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment

scientific article published on 13 December 2006

Citalopram counteracts depressive-like symptoms evoked by chronic social stress in rats

scientific article published in February 2006

Clinical improvement in a case of frontotemporal dementia under aripiprazole treatment corresponds to partial recovery of disturbed frontal glucose metabolism

scientific article

Clinical relevance of TDM of SSRIs

scientific article published on 01 October 2006

Clinical response in a risperidone-medicated naturalistic sample: patients' characteristics and dose-dependent pharmacokinetic patterns

scientific article

Clinical utility of drug measurement and pharmacokinetics: therapeutic drug monitoring in psychiatry

scientific article published on 15 January 2008

Cognitive Behavioral Therapy Versus Sertraline in Patients With Depression and Poorly Controlled Diabetes: The Diabetes and Depression (DAD) Study: A Randomized Controlled Multicenter Trial

scientific article

Column switching and high-performance liquid chromatography in the analysis of amitriptyline, nortriptyline and hydroxylated metabolites in human plasma or serum

scientific article published on July 24, 1992

Concentration-Effect Relationships of Psychoactive Drugs and the Problem to Calculate Therapeutic Reference Ranges

scientific article published on 01 April 2019

Consensus Guideline Based Therapeutic Drug Monitoring (TDM) in Psychiatry and Neurology

scientific article published on 01 January 2016

Consensus guideline for therapeutic drug monitoring in psychiatry (2004): Bibliometric analysis of citations for the period 2004-2011.

scientific article published on 23 September 2015

Correction to: Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations

scientific article published on 12 September 2020

Cytochrome P450-mediated inhibition of venlafaxine metabolism by trimipramine

scientific article published on 01 September 2019

Cytochrome P450-mediated interaction between perazine and risperidone: implications for antipsychotic polypharmacy.

scientific article published on 4 February 2017

Desomorphine goes "crocodile".

scientific article

Detection of TOAD-64 in adult rat brain as revealed by two-dimensional protein gel electrophoresis followed by MALDI mass spectrometry possible modulatory effect of chronic haloperidol treatment

scientific journal article

Determination of citalopram and escitalopram together with their active main metabolites desmethyl(es-)citalopram in human serum by column-switching high performance liquid chromatography (HPLC) and spectrophotometric detection

scientific article published on 16 November 2006

Determination of clozapine and its major metabolites in human serum using automated solid-phase extraction and subsequent isocratic high-performance liquid chromatography with ultraviolet detection

scientific article published on 01 December 1992

Determination of naltrexone and 6beta-naltrexol in human blood: comparison of high-performance liquid chromatography with spectrophotometric and tandem-mass-spectrometric detection.

scientific article published on 28 November 2009

Development of Obsessive-Compulsive Symptoms Following Abrupt Discontinuation of Venlafaxine

scientific article published on 12 February 2020

Differences in Duloxetine Dosing Strategies in Smoking and Nonsmoking Patients: Therapeutic Drug Monitoring Uncovers the Impact on Drug Metabolism

scientific article published on 04 September 2018

Differential effects of escitalopram on attention: a placebo-controlled, double-blind cross-over study

scientific article published on 16 September 2009

Distribution pattern of mirtazapine and normirtazapine in blood and CSF.

scientific article published on 23 August 2014

Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Mental Well-Being in Schizophrenia: Results From the Randomized NeSSy Trial

scientific article published on 01 November 2019

Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas

scientific article published on 15 April 2010

Dose-Related Concentrations of Neuroactive/Psychoactive Drugs Expected in Blood of Children and Adolescents

scientific article published on 01 April 2020

Drug safety and adverse drug reaction reporting behavior related to outpatient opioid replacement therapy: Results from a survey among physicians

scientific article

Drug-Induced Liver Injury Associated With Antidepressive Psychopharmacotherapy: An Explorative Assessment Based on Quantitative Signal Detection Using Different MedDRA Terms

scientific article published on 16 October 2015

Duloxetine enters the brain - But why is it not found in the cerebrospinal fluid

scientific article published on 25 September 2015

Early reactions of brain-derived neurotrophic factor in plasma (pBDNF) and outcome to acute antidepressant treatment in patients with Major Depression

scientific article published on 22 July 2011

Effect of chronic citalopram on serotonin-related and stress-regulated genes in the dorsal raphe nucleus of the rat.

scientific article published on 19 December 2006

Effect of smoking on risperidone pharmacokinetics - A multifactorial approach to better predict the influence on drug metabolism.

scientific article published on 16 December 2016

Effects of Pulsed High-Frequency Electromagnetic Fields on the Neuroendocrine System ⬇️

scientific article published on February 1, 1998

Effects of antipsychotic treatment on cognition in healthy subjects

scientific article published on 31 October 2012

Effects of antipsychotic treatment on psychopathology and motor symptoms. A placebo-controlled study in healthy volunteers

scientific article published on 04 June 2011

Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stress

scientific article

Effects of fluoxetine on behavioral deficits evoked by chronic social stress in rats

scientific article published in September 2006

Effects of short-term exposure to catecholestrogens on catecholamine turnover in the preoptic-hypothalamic brain of ovariectomized rats ⬇️

scientific article published on May 27, 1982

Effects of the Proton Pump Inhibitors Omeprazole and Pantoprazole on the Cytochrome P450-Mediated Metabolism of Venlafaxine

scientific article published on 2 September 2017

Effects on enantiomeric drug disposition and open-field behavior after chronic treatment with venlafaxine in the P-glycoprotein knockout mice model

scientific article

Elevated Clozapine Concentrations in Clozapine-Treated Patients with Hypersalivation

scientific article published on 01 October 2020

Elevated quetiapine serum concentrations in a patient treated concomitantly with doxepin, lorazepam, and pantoprazole

scientific article published in October 2004

Elevated risperidone serum concentrations during acute inflammation, two cases

scientific article published on 7 October 2015

Enhancement of human cortico-motoneuronal excitability by the selective norepinephrine reuptake inhibitor reboxetine.

scientific article published in September 2002

Evaluation of P-glycoprotein (abcb1a/b) modulation of [(18)F]fallypride in MicroPET imaging studies

scientific article

Evaluation of naltrexone for dissociative symptoms in borderline personality disorder

scientific article published in January 2012

Evidence that 3α-hydroxy-5α-pregnan-20-one is a physiologically relevant modulator of gaba-ergic neurotransmission ⬇️

scientific article published on January 1, 1991

First-Episode Psychosis Possibly due to Roxithromycin-Related Inhibition of Metabolization of Tetrahydrocannabinol

scientific article published in June 2017

Flupentixol: relevance of stereoselective therapeutic drug monitoring

scientific article

Fluvoxamine augmentation of olanzapine in chronic schizophrenia: pharmacokinetic interactions and clinical effects

scientific article published in October 2002

Free-choice ethanol consumption under the influence of GABAergic drugs in rats

scientific article published in April 2002

French summaries of product characteristics: content in relation to therapeutic monitoring of psychotropic drugs

scientific article published on 22 February 2010

HPMA Based Amphiphilic Copolymers Mediate Central Nervous Effects of Domperidone

scientific article published on 5 April 2011

Haloperidol and risperidone have specific effects on altered pain sensitivity in the ketamine model of schizophrenia

scientific article published on 23 September 2008

Hamilton depression rating subscales to predict antidepressant treatment outcome in the early course of treatment.

scientific article published on 24 December 2014

High mirtazapine plasma levels in infant after breast feeding: case report and review of the literature.

scientific article

High striatal occupancy of D2-like dopamine receptors by amisulpride in the brain of patients with schizophrenia

scientific article

High venlafaxine serum levels after prior fluoxetine medication

scientific article published in April 2012

Hormonal influences on cardiovascular norepinephrine transporter responses in healthy women

scientific article published on 7 February 2008

How does the benzamide antipsychotic amisulpride get into the brain?--An in vitro approach comparing amisulpride with clozapine

scientific article

Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds--implications for pharmacokinetics of selected substrates

scientific article

Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting

scientific article

In vitro P-glycoprotein efflux inhibition by atypical antipsychotics is in vivo nicely reflected by pharmacodynamic but less by pharmacokinetic changes

scientific article

Increased CSF APPs-α levels in patients with Alzheimer disease treated with acitretin

scientific article

Induction of Drug Transporters Alters Disposition of Risperidone - A Study in Mice

scientific article published on 2 June 2010

Inflammation and psychotropic drugs: the relationship between C-reactive protein and antipsychotic drug levels

scientific article published on 3 June 2015

Inhibition of dextromethorphan metabolism by moclobemide ⬇️

scientific article published on January 1, 1998

Inhibitory potencies of trimipramine and its main metabolites at human monoamine and organic cation transporters

scientific article published on 12 April 2011

Interaction of modafinil and clomipramine as comedication in a narcoleptic patient

scientific article published on March 1, 1998

Interactions and monitoring of antipsychotic drugs

scientific article published on January 2012

Lack of Smoking Effects on Pharmacokinetics of Oral Paliperidone-analysis of a Naturalistic Therapeutic Drug Monitoring Sample

scientific article published on 06 August 2020

Lamotrigine in pregnancy - therapeutic drug monitoring in maternal blood, amniotic fluid, and cord blood

scientific article published in September 2015

Large variability of aripiprazole and dehydroaripiprazole serum concentrations in adolescent patients with schizophrenia

scientific article published in August 2008

Low concentration of ziprasidone in human milk: a case report

scientific article published on 10 February 2009

Low novelty seeking and high self directedness scores in alcohol-dependent patients without comorbid psychiatric disorders homozygous for the A10 allele of the dopamine transporter gene

scientific article published in March 2010

Making the Case for 'Power Abuse Disorder' as a Nosologic Entity

scientific article

Measurement of duloxetine in blood using high-performance liquid chromatography with spectrophotometric detection and column switching

scientific article published in December 2007

Measuring citalopram in blood and cerebrospinal fluid: revealing a distribution pattern that differs from other antidepressants

scientific article published on 01 May 2016

Melperone but not bisoprolol or metoprolol is a clinically relevant inhibitor of CYP2D6: evidence from a therapeutic drug monitoring survey

scientific article published on 5 May 2015

Metamizole but not Ibuprofen reduces the plasma concentration of sertraline - Implications for the concurrent treatment of pain and depression/anxiety disorders

scientific article published on 11 July 2020

Methylphenidate challenge test in adults with attention deficit/hyperactivity disorder (ADHD): Clinical effects and their predictors

scientific article published on 12 August 2020

Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of carbamazepine and its main metabolites ⬇️

scientific article published on 01 August 1998

Molecular cloning of rat G-protein-coupled receptor kinase 6 (GRK6) from brain tissue, and its mRNA expression in different brain regions and peripheral tissues ⬇️

scientific article published on October 3, 1997

Monitoring Serum Concentrations of Clomipramine and Metabolites: Fluorescence Polarization Immunoassay Versus High Performance Liquid Chromatography ⬇️

scientific article published on 01 July 1997

New dopamine D2 receptor polymorphisms in rats and association with apomorphine-induced stereotypies

scientific article published in February 2002

No effect of six weeks of treatment with escitalopram on mood in healthy volunteers--irrespective of genotype for the promoter of the serotonin transporter

scientific article published on 29 October 2008

Nocturnal hormone profiles in patients with schizophrenia treated with olanzapine

scientific article published on 26 September 2005

Non-adherence to psychotropic medication assessed by plasma level in newly admitted psychiatric patients: Prevalence before acute admission

scientific article published on 22 January 2019

Nonlinear Pharmacokinetics of Fluvoxamine and Gender Differences ⬇️

scientific article published on August 1, 1998

Olanzapine: Pharmacology, Pharmacokinetics and Therapeutic Drug Monitoring ⬇️

scientific article published on December 1, 2001

Over-expression of two different forms of the alpha-secretase ADAM10 affects learning and memory in mice

scientific article published on 2 October 2006

P-glycoprotein influence on the brain uptake of a 5-HT(2A) ligand: [(18)F]MH.MZ

scientific article published on 08 February 2011

PT705. Therapeutic Drug Monitoring (TDM) in maternal serum, amniotic fluid and umbilical cord blood during pregnancy and delivery.

scientific article published on 27 May 2016

Peripheral blood and neuropsychological markers for the onset of action of antidepressant drugs in patients with Major Depressive Disorder

scientific article

Personalised medicine in psychiatry? Yes, but how?

scientific article published in December 2014

Pharmacodynamic Drug-Drug interactions of QT-prolonging drugs in hospitalized psychiatric patients

scientific article published on 08 January 2021

Pharmacodynamic Effects of Aripiprazole and Ziprasidone with Respect to P-Glycoprotein Substrate Properties ⬇️

scientific article published on June 4, 2013

Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice

scientific article published on 21 November 2007

Pharmacokinetic Drug-Drug Interactions of Mood Stabilizers and Risperidone in Patients Under Combined Treatment

scientific article

Pharmacokinetic considerations in antipsychotic augmentation strategies: How to combine risperidone with low-potency antipsychotics

scientific article published on 13 March 2017

Pharmacokinetic correlates of venlafaxine: associated adverse reactions

scientific article published on 28 March 2019

Pharmacokinetic interactions between clozapine and sertraline in smokers and non-smokers

scientific article published on 19 April 2020

Pharmacokinetic patterns of risperidone-associated adverse drug reactions

scientific article published on 4 July 2016

Pharmacokinetics of acute and sub-chronic aripiprazole in P-glycoprotein deficient mice

scientific article published on 3 July 2010

Pharmacokinetics of risperidone in different application forms - Comparing long-acting injectable and oral formulations

scientific article

Pharmacokinetics of venlafaxine in treatment responders and non-responders: a retrospective analysis of a large naturalistic database

scientific article published on 09 April 2019

Pharmacological validation of a chronic social stress model of depression in rats: effects of reboxetine, haloperidol and diazepam

scientific article published in May 2008

Phenotyping and genotyping of drug metabolism to guide pharmacotherapy in psychiatry

scientific article published on February 2013

Plasma levels and cerebrospinal fluid penetration by duloxetine in a patient with a non-fatal overdose during a suicide attempt

scientific article published on 6 August 2009

Population pharmacokinetic analysis of mirtazapine

scientific article

Potential cost-effectiveness of therapeutic drug monitoring for depressed patients treated with citalopram

scientific article published in June 2013

Potentially inappropriate medication in older psychiatric patients

scientific article published on 08 October 2020

Preferential uptake of norepinephrine into dopaminergic terminals of a synaptosomal preparation from rat cerebral cortex ⬇️

scientific article published on May 28, 1984

Pregabalin abuse and dependence in Germany: results from a database query

scientific article

Prevalence and sort of pharmacokinetic drug-drug interactions in hospitalized psychiatric patients

scientific article published on 09 June 2020

Psychopharmacotherapy in patients with cardiovascular diseases ⬇️

scientific article published on 01 November 2012

QTc Time Correlates with Amitriptyline and Venlafaxine Serum Levels in Elderly Psychiatric Inpatients

scientific article published on 21 February 2018

Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride.

scientific article

Quetiapine and norquetiapine serum concentrations and clinical effects in depressed patients under augmentation therapy with quetiapine

scientific article published in August 2013

Randomized controlled study of early medication change for non-improvers to antidepressant therapy in major depression--The EMC trial

scientific article

Rapid and reliable genotyping procedure for detection of alleles with mutations, deletion, or/and duplication of the CYP2D6 gene.

scientific article published on 22 April 2009

Rationale and design of the randomised clinical trial comparing early medication change (EMC) strategy with treatment as usual (TAU) in patients with major depressive disorder--the EMC trial

scientific article

Recommendations for therapeutic monitoring of antidepressants

scientific article published on March 13, 2013

Reduced clearance of venlafaxine in a combined treatment with quetiapine

scientific article published on 25 April 2018

Relation between leukocyte counts and cortisol secretion in CML patients undergoing combined TNF alpha/IFN alpha therapy

scientific article published on September 1, 1992

Risperidone-induced extrapyramidal side effects: is the need for anticholinergics the consequence of high plasma concentrations?

scientific article

Rotarod impairment: catalepsy-like screening test for antipsychotic side effects

scientific article published in January 2009

Safety of Psychotropic Medications in People With COVID-19: Evidence Review and Practical Recommendations

scientific article published on 01 October 2020

Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations

scientific article published on 15 July 2020

Schizophrenic patients who smoke have a faster finger tapping rate than non-smokers

scientific article published in April 2002

Serotonergic modulation of response inhibition and re-engagement? Results of a study in healthy human volunteers.

scientific article published on August 2010

Serotonin syndrome as a result of fluoxetine in a patient with tramadol abuse: plasma level-correlated symptomatology

scientific article published in August 2002

Serum concentrations of hydroxybupropion for dose optimization of depressed patients treated with bupropion

scientific article published in August 2014

Serum concentrations of paliperidone versus risperidone and clinical effects

scientific article published in April 2010

Serum levels of aripiprazole and dehydroaripiprazole, clinical response and side effects

scientific article published on 01 January 2008

Severe adverse drug events under combination of nortriptyline and melperone due to pharmacokinetic interaction

scientific article

Severe tremor after cotrimoxazole-induced elevation of venlafaxine serum concentrations in a patient with major depressive disorder

scientific article published in June 2013

Sex and body weight are major determinants of venlafaxine pharmacokinetics

scientific article published on 01 November 2018

Side effects related to potentially inappropriate medications in elderly psychiatric patients under everyday pharmacotherapy

scientific article published on 23 December 2014

Stimulation of immediate early gene expression by desipramine in rat brain ⬇️

scientific article published on September 1, 1997

Strain Differences in Open-Field and Elevated Plus-Maze Behavior of Rats Without and With Pretest Handling ⬇️

scientific article published on April 1, 1998

Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone).

scientific article published on December 2008

Study protocol of the Diabetes and Depression Study (DAD): a multi-center randomized controlled trial to compare the efficacy of a diabetes-specific cognitive behavioral group therapy versus sertraline in patients with major depression and poorly co

scientific article

Sub-acute effects of interferon-alpha 2 on adrenocorticotrophic hormone, cortisol, growth hormone and prolactin in humans

scientific article published on October 1, 1992

TDM in psychiatry and neurology: A comprehensive summary of the consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology, update 2017; a tool for clinicians<sup/>.

scientific article published in March 2018

The "DGPPN-Cohort": A national collaboration initiative by the German Association for Psychiatry and Psychotherapy (DGPPN) for establishing a large-scale cohort of psychiatric patients

scientific article published on 3 April 2013

The AGNP-TDM Expert Group Consensus Guidelines: focus on therapeutic monitoring of antidepressants.

scientific article

The Acid Sphingomyelinase Sequence Variant p.A487V Is Not Associated With Decreased Levels of Enzymatic Activity

scientific article published on 26 May 2012

The Effect of Age, Sex, Smoking and Co-Medication on Serum Levels of Venlafaxine and O-Desmethylvenlafaxine under Naturalistic Conditions ⬇️

scientific article published on March 16, 2012

The Effects of Co-prescription of Pantoprazole on the Clozapine Metabolism

scientific article published on 15 October 2019

The N-demethylation of the doxepin isomers is mainly catalyzed by the polymorphic CYP2C19.

scientific article published in July 2002

The Serotonin Transporter Promoter Polymorphism (5-HTTLPR) Affects the Relation between Antidepressant Serum Concentrations and Effectiveness in Major Depression ⬇️

scientific article published on November 15, 2011

The TPH intron 7 A218C polymorphism and TCI dimension scores in alcohol-dependent patients: hints to nonspecific psychopathology.

scientific article

The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders

scientific article published in February 2002

The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: a pilot study

scientific article published on 20 August 2010

The neuroendocrinological profile of roxindole, a dopamine autoreceptor agonist, in schizophrenic patients ⬇️

scientific article published on 01 February 1995

The striatal and extrastriatal D2/D3 receptor-binding profile of clozapine in patients with schizophrenia

scientific article published in May 2006

The use of ziprasidone in clinical practice: analysis of pharmacokinetic and pharmacodynamic aspects from data of a drug monitoring survey

scientific article

The value of drug and metabolite concentration in blood as a biomarker of psychopharmacological therapy

scientific article published on October 2013

Therapeutic Drug Monitoring in Psychiatry ⬇️

scientific article published on September 27, 2011

Therapeutic Drug Monitoring of Long-Acting Injectable Antipsychotic Drugs

scientific article published on 04 November 2020

Therapeutic Drug Monitoring of Naltrexone and 6β-Naltrexol During Anti-craving Treatment in Alcohol Dependence: Reference Ranges

scientific article published on 01 January 2019

Therapeutic drug monitoring for antidepressant drug treatment

scientific article published on January 2012

Therapeutic drug monitoring for drugs used in the treatment of substance-related disorders: literature review using a therapeutic drug monitoring appropriateness rating scale

scientific article published on October 2011

Therapeutic drug monitoring for optimizing amisulpride therapy in patients with schizophrenia

scientific article published in December 2005

Therapeutic drug monitoring for patients with Alzheimer dementia to improve treatment with donepezil

scientific article published in June 2015

Therapeutic drug monitoring in neuropsychopharmacology: does it hold its promises?

scientific article published on March 2008

Therapeutic drug monitoring of the antidepressant mirtazapine and its N-demethylated metabolite in human serum.

scientific article published in February 2004

Therapeutic drug monitoring-based clozapine dosing recommendations

scientific article published on 01 February 2007

Therapeutic monitoring of aripiprazole by HPLC with column-switching and spectrophotometric detection

scientific article published in September 2005

Therapeutic monitoring of new antipsychotic drugs

scientific article published in April 2004

Tiagabine, a gamma-amino-butyric acid transporter inhibitor impairs spatial learning of rats in the Morris water-maze

scientific journal article

Time course of the effects of steroid hormone deprivation elicited by ovariectomy or ovariectomy plus adrenalectomy on the affinity and density of GABA binding sites in distinct rat brain areas ⬇️

scientific article published on 01 January 1995

Tolerability of High-Dose Venlafaxine After Switch From Escitalopram in Nonresponding Patients With Major Depressive Disorder

scientific article published on 16 November 2020

Toxic clozapine serum levels during inflammatory reactions.

scientific article published in August 2009

Tyrosine hydroxylase Val-81-Met polymorphism associated with early-onset alcoholism

scientific article

Update Opipramol

scientific article published on 20 March 2017

Venlafaxine and O-desmethylvenlafaxine concentrations in plasma and cerebrospinal fluid

scientific article published in January 2015

WITHDRAWN: Association analysis between the early change of serum brain-derived neurotrophic factor (sBDNF) and final change of depression severity during antidepressant treatment: A pilot study

retracted scientific article published on 13 December 2010

What the clinician still has to be reminded of

scientific article published on 01 October 2004

Why do antidepressant therapies have such a poor success rate?

scientific article published on 28 March 2016

[Different number of contraindications between summaries of product characteristics (SmPC) of drugs with the same active ingredients - an analysis of data from SmPCs of neuropsychiatric drugs]

scientific article published on 24 May 2019

[Drug-drug-interactions in psychiatry]

scientific article published on 23 January 2013

[Erratum to: Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP]

scientific article published on 01 September 2019

[Important to atypical antipsychotics: pharmacokinetics, interaction potential and therapeutic drug monitoring]

scientific article published on 01 January 2002

[Individualized treatment with tricyclic antidepressives. The pharmacogenetics of depression]

scientific article published on 01 January 2008

[Pharmacogenetics, therapeutic drug monitoring and non compliance]

scientific article published on 01 June 2010

[Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP]

scientific article published on 01 May 2019

[Therapeutic drug monitoring of new antidepressives and antipsychotics]

scientific article published on 01 May 2003

[Use of summaries of product characteristics (SmPC) among family doctors and pharmacists in the context of the aut-idem regulation: Results of an exploratory cross-sectional survey]

scientific article published on 19 May 2020

hs-CRP Predicts Improvement in Depression in Patients With Type 1 Diabetes and Major Depression Undergoing Depression Treatment: Results From the Diabetes and Depression (DAD) Study

scientific article published on 3 August 2016

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