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List of works by Bernard Pirotte

2,2-Dimethyl-3,4-dihydro-2H-1,4-benzoxazines as isosteres of 2,2-dimethylchromans acting as inhibitors of insulin release and vascular smooth muscle relaxants

A new potential cyclooxygenase-2 inhibitor, pyridinic analogue of nimesulide

scientific article

Advances in the field of COX-2 inhibition

BM-573 inhibits the development of early atherosclerotic lesions in Apo E deficient mice by blocking TP receptors and thromboxane synthase

scientific article published on 21 March 2011

Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig.

scientific article published on 23 March 2005

Design, synthesis, and SAR study of a series of N-alkyl-N'-[2-(aryloxy)-5-nitrobenzenesulfonyl]ureas and -cyanoguanidine as selective antagonists of the TPalpha and TPbeta isoforms of the human thromboxane A2 receptor.

scientific article

Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors

scientific article published in December 2004

Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds

scientific article published on 08 June 2018

Evaluation of original dual thromboxane A2 modulators as antiangiogenic agents

scientific journal article

First and second generations of COX-2 selective inhibitors

scientific article published in August 2004

From the design to the clinical application of thromboxane modulators

scientific article

Fully Automated Synthesis and Evaluation of [18 F]BPAM121: Potential of an AMPA Receptor Positive Allosteric Modulator as PET Radiotracer

scientific article published on 22 February 2019

GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11

scientific article published on 21 September 2020

In vitro and in vivo pharmacological characterization of BM-613 [N-n-pentyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea], a novel dual thromboxane synthase inhibitor and thromboxane receptor antagonist.

scientific article published on 30 December 2004

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

scientific article published on 04 November 2020

Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs?

scientific article published on 24 December 2008

Modulation of the arachidonic cascade with omega3 fatty acids or analogues: potential therapeutic benefits

scientific article published in August 2004

N-(3-Phenoxy-4-pyridinio)methanesulfonamidate

scientific article published on 23 January 2002

New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators

scientific article published on May 2004

New developments on thromboxane and prostacyclin modulators part II: prostacyclin modulators

scientific article published on May 2004

New developments on thromboxane modulators.

scientific article published in August 2004

Pharmacological characterization of N-tert-butyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a novel thromboxane, etc.

scientific article (publication date: May 2004)

Polyhydroxybenzoic acid derivatives as potential new antimalarial agents

scientific article published in 2021

Progress in the field of GPIIb/IIIa antagonists

scientific article published in April 2004

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung

scientific article published on 22 December 2020

Recent development in the field of dual COX / 5-LOX inhibitors

scientific article published in August 2004

Spectral and crystallographic study of pyridinic analogues of nimesulide: determination of the active form of methanesulfonamides as COX-2 selective inhibitors

scientific article published in November 2002

Structure-based pharmacophore of COX-2 selective inhibitors and identification of original lead compounds from 3D database searching method

scientific article published on 09 October 2006

Synthesis and pharmacological evaluation of 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as novel thromboxane A₂ receptor antagonists.

scientific article published on 23 April 2013

Synthesis and pharmacological evaluation of novel nitrobenzenic thromboxane modulators as antiplatelet agents acting on both the alpha and beta isoforms of the human thromboxane receptor

scientific article published on 01 June 2006

Therapeutic applications of prostaglandins and thromboxane A2 inhibitors in abdominal aortic aneurysms

scientific article published on 27 December 2017

Therapeutic potential of thromboxane inhibitors in asthma

scientific article

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