List of works - Claude Libert

A New Venue of TNF Targeting

scientific article published on 2 April 2018

A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice

scientific article published on 08 November 2019

A fully dissociated compound of plant origin for inflammatory gene repression

scientific article

Alpha(1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties

scientific article

Altered desialylated plasma N-glycan profile in patients with non-small cell lung carcinoma

scientific article published on June 8, 2012

An extracellular microRNA can rescue lives in sepsis

scientific article published on 14 November 2019

An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17.

scientific article published on 31 October 2014

Caspase-14 protects against epidermal UVB photodamage and water loss

scientific article

Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation

scientific article

Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro.

scientific article published on 21 June 2014

Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization

scientific article published on 23 December 2019

Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes

scientific article

Controlling complexity: the clinical relevance of mouse complex genetics

scientific article

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

scholarly article by Marcin F Osuchowski et al published October 2018 in Infection

DUSP3 Genetic Deletion Confers M2-like Macrophage-Dependent Tolerance to Septic Shock

scientific article published on 15 April 2015

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways

scientific journal article

Efficient analysis of mouse genome sequences reveal many nonsense variants

scientific article published on 04 May 2016

Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases

scientific article

GILZ in sepsis: "Poor is the pupil who does not surpass his master"

scientific article published on 13 March 2020

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

scientific article

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

scientific article published on 25 June 2018

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1.

scientific article

Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.

scientific article published on 17 July 2015

Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system

scientific article published on 08 May 2020

Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

scientific article published on 09 January 2020

How glucocorticoids control their own strength and the balance between pro- and anti-inflammatory mediators

scientific article

Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy

scientific article

Hypoxia-inducible factors in metabolic reprogramming during sepsis

scientific article published on 23 January 2020

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.

scientific article published on 05 September 2016

In vitro and in vivo protein-bound tyrosine nitration characterized by diagonal chromatography

scientific article

Increased Glucocorticoid Receptor Expression and Activity Mediate the LPS Resistance of SPRET/EI Mice ⬇️

scientific article published on July 27, 2010

Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

scientific article

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome ⬇️

scientific article published on March 1, 2013

Learning lessons in sepsis from the children.

scientific article

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.

scientific article published on 05 October 2009

MARK-AGE biomarkers of ageing

scientific article

MMP-2 and MMP-9 synergize in promoting choroidal neovascularization

scientific article

Matrilysin (matrix metalloproteinase-7): a new promising drug target in cancer and inflammation?

scientific article published on April 2004

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.

scientific article published on 30 May 2013

Matrix metalloproteinase-8: cleavage can be decisive

scientific article published on 3 July 2006

MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation

scientific article published in 2024

Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis

scientific article

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

scholarly article by Marcin F. Osuchowski et al published 14 August 2018 in Infection

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

Modulation of Dendritic Cells by Lipid Grafted Polyelectrolyte Microcapsules

scientific article published on 14 June 2012

Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics

scientific article

N-glycome Profile Levels Relate to Silent Brain Infarcts in a Cohort of Hypertensives

scientific article published on 23 November 2015

N-glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters

scientific article

Nonclassical export pathway: overexpression of NCE102 reduces protein and DNA damage and prolongs lifespan in an SGS1 deficient Saccharomyces cerevisiae

scientific article

Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis

scientific article published on 01 August 2019

Plasma N-Glycome Signature of Down Syndrome

scientific article published on 3 September 2015

Preeclampsia transforms membrane N-glycome in human placenta.

scientific article

Protein modification and maintenance systems as biomarkers of ageing.

scientific article

Proteome-scale Binary Interactomics in Human Cells

scientific article

Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?

scientific article published on 01 August 2018

Role for neutrophils in host immune responses and genetic factors that modulate resistance to Salmonella enterica serovar typhimurium in the inbred mouse strain SPRET/Ei

scientific article

Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds

scientific article

Should we inhibit type I interferons in sepsis?

scientific article published on 25 September 2006

Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability

scientific article

TNFR1 inhibition with a Nanobody protects against EAE development in mice

scientific article

The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrier

scientific article

The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production

scholarly article

Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1.

scientific article published on October 2011

Tumor necrosis factor inhibits glucocorticoid receptor function in mice: a strong signal toward lethal shock

scientific article

Turning a pathogen protein into a therapeutic tool for sepsis

scientific article published on 17 December 2020

Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.

scientific article

Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium

scientific article published on 11 September 2020

mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells

scientific article published on 25 August 2011

List of works by Claude Libert

A New Venue of TNF Targeting

A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice

A fully dissociated compound of plant origin for inflammatory gene repression

Alpha(1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties

Altered desialylated plasma N-glycan profile in patients with non-small cell lung carcinoma

An extracellular microRNA can rescue lives in sepsis

An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17.

Caspase-14 protects against epidermal UVB photodamage and water loss

Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation

Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro.

Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization

Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes

Controlling complexity: the clinical relevance of mouse complex genetics

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

DUSP3 Genetic Deletion Confers M2-like Macrophage-Dependent Tolerance to Septic Shock

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways

Efficient analysis of mouse genome sequences reveal many nonsense variants

Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases

GILZ in sepsis: "Poor is the pupil who does not surpass his master"

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1.

Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.

Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system

Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

How glucocorticoids control their own strength and the balance between pro- and anti-inflammatory mediators

Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy

Hypoxia-inducible factors in metabolic reprogramming during sepsis

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.

In vitro and in vivo protein-bound tyrosine nitration characterized by diagonal chromatography

Increased Glucocorticoid Receptor Expression and Activity Mediate the LPS Resistance of SPRET/EI Mice ⬇️

Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome ⬇️

Learning lessons in sepsis from the children.

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.

MARK-AGE biomarkers of ageing

MMP-2 and MMP-9 synergize in promoting choroidal neovascularization

Matrilysin (matrix metalloproteinase-7): a new promising drug target in cancer and inflammation?

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.

Matrix metalloproteinase-8: cleavage can be decisive

MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation

Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

Modulation of Dendritic Cells by Lipid Grafted Polyelectrolyte Microcapsules

Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics

N-glycome Profile Levels Relate to Silent Brain Infarcts in a Cohort of Hypertensives

N-glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters

Nonclassical export pathway: overexpression of NCE102 reduces protein and DNA damage and prolongs lifespan in an SGS1 deficient Saccharomyces cerevisiae

Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis

Plasma N-Glycome Signature of Down Syndrome

Preeclampsia transforms membrane N-glycome in human placenta.

Protein modification and maintenance systems as biomarkers of ageing.

Proteome-scale Binary Interactomics in Human Cells

Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?

Role for neutrophils in host immune responses and genetic factors that modulate resistance to Salmonella enterica serovar typhimurium in the inbred mouse strain SPRET/Ei

Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds

Should we inhibit type I interferons in sepsis?

Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability

TNFR1 inhibition with a Nanobody protects against EAE development in mice

The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrier

The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production

Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1.

Tumor necrosis factor inhibits glucocorticoid receptor function in mice: a strong signal toward lethal shock

Turning a pathogen protein into a therapeutic tool for sepsis

Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.

Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium

mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells