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List of works by Yibin Kang

A Five-Species Jungle Game

scientific article

A biomimetic 3D model of hypoxia-driven cancer progression

scientific article published on 22 August 2019

A bridge between melanoma cell states

scientific article published on 01 August 2020

A multigenic program mediating breast cancer metastasis to bone

scientific article (publication date: June 2003)

A new Lnc in metastasis: long noncoding RNA mediates the prometastatic functions of TGF-β.

scientific article published on May 2014

A novel mouse model for non-invasive single marker tracking of mammary stem cells in vivo reveals stem cell dynamics throughout pregnancy

scientific article

A one-two punch of miR-126/126* against metastasis

scientific article published in March 2013

A quantitative atlas of histone modification signatures from human cancer cells

scientific article published on 05 July 2013

A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells.

scientific article

ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

scientific article published on 16 July 2009

ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP

scientific article published on 17 September 2020

Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma

scientific article

Acute infection induces a metastatic niche: a double menace for cancer patients

scientific article published on 6 August 2013

An open letter to the FDA and other regulatory agencies: Preclinical drug development must consider the impact on metastasis

scientific article

Analysis of cancer stem cell metastasis in xenograft animal models

scientific article published in January 2009

Aspiration promotes cooperation in the prisoner's dilemma game with the imitation rule

scientific article published on 18 July 2016

Author Correction: Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability

scientific article published in Nature Communications

Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

scientific article published on 30 October 2014

Beyond tumorigenesis: cancer stem cells in metastasis

scientific article

Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate.

scientific article published on 7 August 2017

Bone marrow stroma-derived miRNAs as regulators, biomarkers and therapeutic targets of bone metastasis

scientific article

Bone metastases detection by circulating biomarkers: OPG and RANK-L.

scientific article published on 13 April 2011

Bone metastasis and the metastatic niche

scientific article

Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis

scientific article published on 15 April 2019

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

scientific article

CD44 splice isoform switching determines breast cancer stem cell state

scientific article published on 28 January 2019

Cell fusion as a hidden force in tumor progression

scientific article

Cell fusion hypothesis of the cancer stem cell

scientific article published on January 2011

Cell lineage determinants as regulators of breast cancer metastasis

scientific article published on 19 November 2016

Cellular Plasticity in Bone Metastasis

scientific article published on 15 October 2020

Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone

scientific article published on 31 August 2009

Comparative functional characterization of the feline foamy virus transactivator reveals its species specificity

scientific article published in January 2004

Complex interplay between tumor microenvironment and cancer therapy

scientific article published on 10 August 2018

Context-dependent EMT programs in cancer metastasis

scientific article published on 11 April 2019

Corrigendum: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

scientific article published on 01 December 2016

Cradle of evil: osteogenic niche for early bone metastasis

scientific article published on 01 February 2015

Current preclinical models for the advancement of translational bladder cancer research

scientific article published on 26 December 2012

Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa

scientific article published on 14 September 2020

DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis

scientific article published on 03 March 2014

Detection of a common chimeric transcript between human chromosomes 7 and 16.

scientific article

Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2

scientific article published on 17 September 2020

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

scientific article

Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis

scientific article

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

scientific article

Distinctive properties of metastasis-initiating cells

scientific article

Dll1<sup>+</sup> quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway

scientific article published on 18 January 2021

Dysregulation of developmental pathways in bone metastasis

scientific article published on 12 July 2010

E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1

scientific article published on 20 August 2020

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

scientific article (publication date: 12 July 2002)

EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors by osteoblasts: implications for osteolytic bone metastases

scientific article published on 17 July 2007

Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variants

scholarly article

Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2

scientific article (publication date: 21 October 2012)

Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling

scientific article published on July 2012

Emerging therapeutic targets in metastatic progression: A focus on breast cancer

scientific article published on 18 March 2016

Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo

scientific article

Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis

scientific article published on 01 May 2019

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells

scientific article

Epithelial-mesenchymal transitions: twist in development and metastasis

scientific article published in August 2004

Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development

scientific article published on 22 September 2020

Ets2 anchors the prometastatic function of mutant p53 in osteosarcoma

scientific article published in September 2017

Extracellular vesicle and particle biomarkers define multiple human cancers

journal article published in 2020

Fixation probabilities in evolutionary games with the Moran and Fermi processes

scientific article published on 11 September 2014

Fixation times in evolutionary games with the Moran and Fermi processes

scientific article published on 25 September 2015

Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes

scientific article

From breast to the brain: unraveling the puzzle of metastasis organotropism

scientific article

From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer

scientific article

Functional genomic analysis of cancer metastasis: biologic insights and clinical implications

scientific article

Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis

scientific article

Global secretome analysis identifies novel mediators of bone metastasis.

scientific article

Glucose-6-phosphate dehydrogenase is not essential for K-Ras-driven tumor growth or metastasis

scientific article published on 13 July 2020

Guidelines and definitions for research on epithelial-mesenchymal transition

scientific article published on 16 April 2020

Hypoxia and hypoxia-inducible factors: master regulators of metastasis

scientific article published on 20 October 2010

Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability

scientific article published in Nature Communications

Identification of Nidogen 1 as a lung metastasis protein through secretome analysis

scientific article

Identification of staphylococcal nuclease domain-containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions

scientific article

Identifying site-specific metastasis genes and functions.

scientific article published on January 2005

Imaging TGFβ Signaling in Mouse Models of Cancer Metastasis

scientific article published in January 2016

Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis

scientific article published on 13 July 2009

In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer.

scientific article

Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line

scientific article published on 05 July 2013

Lipid Metabolism Fuels Cancer's Spread

scientific article published in February 2017

Lnc-ing ROR1-HER3 and Hippo signalling in metastasis

scientific article published in January 2017

Long Noncoding RNA GMAN, Up-regulated in Gastric Cancer Tissues, Is Associated With Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS

scientific article published on 13 November 2018

Loss of the polycomb protein Mel-18 enhances the epithelial–mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer ⬇️

scientific article published on March 11, 2013

MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer

scientific article

MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors

scientific article

Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model

scientific article

Metadherin as a link between metastasis and chemoresistance

scientific article published on 20 July 2009

Metalloproteinases and osteoblast EGFR signaling in osteolytic bone metastasis of breast cancer

scientific article

Metastatic niche functions and therapeutic opportunities

scientific article published on 26 July 2018

MiR-215 modulates gastric cancer cell proliferation by targeting RB1.

scientific article published on 24 August 2013

MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells

scientific article published on 22 March 2011

MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells.

scientific article published on 7 September 2017

MicroRNA-711 is a prognostic factor for poor overall survival and has an oncogenic role in breast cancer

scientific article published on 9 February 2016

MicroRNAs as regulators of bone homeostasis and bone metastasis

scientific article

MicroRNAs as regulators of tumor-associated stromal cells

scientific article

Mouse genomic screen reveals novel host regulator of metastasis

scientific article published on 16 February 2017

Multilayer control of the EMT master regulators ⬇️

scientific article published on April 22, 2013

New tricks against an old foe: molecular dissection of metastasis tissue tropism in breast cancer

scientific article published on January 2006

Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis

scientific article

Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche

scientific article published on 17 May 2018

Notch signaling: mediator and therapeutic target of bone metastasis ⬇️

scientific article published on January 10, 2012

OR30-4 Parathyroid Hormone-related Peptide Antagonist and Inverse Agonist Reduce Breast Cancer Metastasis to Bone and Bone Loss.

scientific article published on 30 April 2019

Optimization of duplex stability and terminal asymmetry for shRNA design

scientific article

Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement

scientific article

Organotropism of breast cancer metastasis

scientific article published on September 2007

PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis

scientific article

Pharmacological disruption of the MTDH–SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer

scientific article

Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

scientific article

Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer

scientific article published on January 2013

Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas

scientific article published on 31 December 2015

Pre-metastatic niches: organ-specific homes for metastases.

scientific article published on 17 March 2017

Pro-metastasis function of TGFbeta mediated by the Smad pathway

scientific article

Probing the Fifty Shades of EMT in Metastasis

scientific article published on February 2016

Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis

scientific article published on 19 June 2013

RAI2: Linking Retinoic Acid Signaling with Metastasis Suppression

scientific article published on May 2015

Rabconnectin-3 is a functional regulator of mammalian Notch signaling

scientific article

Racial profiling harms science

scientific article published on 01 March 2019

Regulation of cancer metastasis by cell-free miRNAs

scientific article

Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway

scientific article

Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway

scientific article published on 01 October 2016

Role Reversal: A Pro-metastatic Function of E-Cadherin

scientific article published on 01 November 2019

Role of RANK, RANKL, OPG, and CXCR4 Tissue Markers in Predicting Bone Metastases in Breast Cancer Patients

scientific article published on 20 July 2011

Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy

scientific article published on 6 April 2017

Short-term and long-term clinical outcomes of uncommon types of invasive breast cancers

scientific article

Signaling pathways in breast cancer metastasis - novel insights from functional genomics

scientific article published on 14 March 2011

Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

scientific article

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

scientific article

Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis

scientific article published on 29 November 2021

SnapShot: Bone Metastasis

scientific article published on 01 October 2012

Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities

scientific article published on 01 December 2020

Structural insights into the tumor-promoting function of the MTDH-SND1 complex.

scientific article

TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer ⬇️

scientific article published on June 18, 2012

Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.

scientific article

Targeting the transforming growth factor-beta signalling pathway in metastatic cancer

scientific article published on 20 March 2010

Targeting tumor-stromal interactions in bone metastasis

scientific article

The Biology of Bone Metastasis

scientific article

The Bony Side of Endothelial Cells in Prostate Cancer

scientific article published in June 2017

The CD44s splice isoform is a central mediator for invadopodia activity

scientific article published on 11 February 2016

The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer

scientific article published on 12 December 2017

The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor

scientific article

The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis

scientific article

The endoplasmic reticulum acts as a platform for ubiquitylated components of nuclear factor κB signaling

scientific article published on 3 September 2013

The importance of developing therapies targeting the biological spectrum of metastatic disease

scientific article published on 17 May 2019

The metastasis-promoting roles of tumor-associated immune cells

scientific article published on 21 March 2013

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

scientific article

The microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasis-suppressive gene prosaposin

scientific article

The multifaceted role of MTDH/AEG-1 in cancer progression

scientific article published on September 2009

The pro-metastatic role of bone marrow-derived cells: a focus on MSCs and regulatory T cells

scientific article

Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy

scientific article published in December 2017

Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis

scientific article published on 25 November 2020

Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling

scientific article published on 03 January 2019

Transcriptional control of cancer metastasis

scientific article

Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis

scientific article

Transplantable mouse tumor models of breast cancer metastasis

scientific article

Trefoil Factor-1 upregulation in estrogen-receptor positive breast cancer correlates with an increased risk of bone metastasis

scientific article published on 26 November 2020

Tumor cell dissemination: emerging biological insights from animal models and cancer patients

scientific article published on May 2013

Tumor metastasis: moving new biological insights into the clinic

scientific article

Tumor-Stroma Interactions in Bone Metastasis: Molecular Mechanisms and Therapeutic Implications

scientific article published on 05 April 2017

Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

scientific article

Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis

scientific article published on October 2013

Tumour exosome integrins determine organotropic metastasis.

scientific article published on 28 October 2015

Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis

scientific article published on 22 August 2017

Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex

scientific article published on 30 January 2014

Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation

scientific article

Unravelling the complexity of metastasis - molecular understanding and targeted therapies

scientific article published on 23 September 2011

Upholding a role for EMT in breast cancer metastasis.

scientific article

Upholding a role for EMT in pancreatic cancer metastasis

scientific article published in July 2017

VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors

scientific article published on December 2011

Welcoming Treat: Astrocyte-Derived Exosomes Induce PTEN Suppression to Foster Brain Metastasis

scientific article published in November 2015

pSTAT3+ Reactive Astrocytes Promote Brain Metastasis

scientific article published on 17 July 2018

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

scientific article

β-Spectrin regulates the hippo signaling pathway and modulates the basal actin network

scientific article

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