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List of works by Walter Mier

(68)Ga-PSMA11-PET/CT in newly diagnosed carcinoma of the prostate: correlation of intraprostatic PSMA uptake with several clinical parameters

scientific article published on 15 June 2017

(99m)Tc complexes with activated ester functions; ligands comprising a 3,4-diamino-benzoate backbone

scientific article published on 01 April 2006

131I-labeled peptides as caspase substrates for apoptosis imaging.

scientific article published in June 2005

68Ga or 18F for Prostate Cancer Imaging?

scientific article

68Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging ⬇️

scientific article published on March 13, 2012

68Ga-PSMA PET/CT and Volumetric Morphology of PET-Positive Lymph Nodes Stratified by Tumor Differentiation of Prostate Cancer.

scientific article published on 21 June 2017

68Ga-labelled recombinant antibody variants for immuno-PET imaging of solid tumours

scientific article

99mTc-pertechnetate uptake in hepatoma cells due to tissue-specific human sodium iodide symporter gene expression

scientific article published on 2 May 2006

A Humanized Anti-CD22-Onconase Antibody-Drug Conjugate Mediates Highly Potent Destruction of Targeted Tumor Cells

scientific article

A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology ⬇️

scientific article published on December 31, 2010

A Polymer/Peptide Complex-Based Sensor Array That Discriminates Bacteria in Urine

scientific article

A Polymer/Peptide Complex-Based Sensor Array That Discriminates Bacteria in Urine

A Slow Maturation Process Renders Hepatitis B Virus Infectious.

scientific article published on 15 June 2016

A dimerized urea-based inhibitor of the prostate-specific membrane antigen for 68Ga-PET imaging of prostate cancer ⬇️

scientific article published on June 6, 2012

A disulfide-constrained miniprotein with striking tumor-binding specificity developed by ribosome display

scientific article published on 20 September 2013

A neuroprotective function for the hematopoietic protein granulocyte-macrophage colony stimulating factor (GM-CSF).

scientific article

A new method for tumor imaging by targeting cancer associated fibroblasts

scientific article published on 6 April 2018

A new prostate carcinoma binding peptide (DUP-1) for tumor imaging and therapy.

scientific article published on January 2005

A novel tool against multiresistant bacterial pathogens - lipopeptide modification of the natural antimicrobial peptide ranalexin for enhanced antimicrobial activity and improved pharmacokinetics.

scientific article

A scavenger peptide prevents methylglyoxal induced pain in mice

scientific article published on 06 December 2016

AAV6. ARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model ⬇️

scientific article published on January 19, 2012

Acid-Mediated Prevention of Aspartimide Formation in Solid Phase Peptide Synthesis ⬇️

scientific article published on October 19, 2012

Advantages in functional imaging of the brain

scientific article

Alkylating benzamides with melanoma cytotoxicity

scientific article published on October 2004

Alkylating benzamides with melanoma cytotoxicity: role of melanin, tyrosinase, intracellular pH and DNA interaction

scientific article published on October 2005

An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo

scientific article

Angiopoietin-2 overexpression in morris hepatoma results in increased tumor perfusion and induction of critical angiogenesis-promoting genes.

scientific article published on September 2006

Angiostatin overexpression in Morris hepatoma results in decreased tumor growth but increased perfusion and vascularization.

scientific article published on March 2006

Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis

scientific article published on May 2016

Biodistribution and pharmacokinetics of the (19)F-labeled radiosensitizer 3-aminobenzamide: assessment by (19)F MR imaging

scientific article published on 26 October 2005

Cancer stratification by molecular imaging

scientific article published on 4 March 2015

Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche

Caspases--their role in apoptosis and other physiological processes as revealed by knock-out studies.

scientific article

Cellular Uptake Quantification of Metalated Peptide and Peptide Nucleic Acid Bioconjugates by Atomic Absorption Spectroscopy

scientific article published on 01 January 2008

Challenges in optimizing a prostate carcinoma binding peptide, identified through the phage display technology.

scientific article

Characterization and development of a peptide (p160) with affinity for neuroblastoma cells.

scientific article published on June 2006

Combination of Phage Display and Molecular Grafting Generates Highly Specific Tumor‐Targeting Miniproteins ⬇️

scientific article published on November 13, 2012

Comparative study of the novel RGD motif-containing ITGαvβ6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.

scientific article published on 19 April 2018

Conjugation of DOTA using isolated phenolic active esters: the labeling and biodistribution of albumin as blood pool marker.

scientific article published on January 2005

Current status in the therapy of liver diseases

scientific article published on 30 April 2014

Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptor

scientific article published on December 2013

DNA Libraries for the Construction of Phage Libraries: Statistical and Structural Requirements and Synthetic Methods ⬇️

scientific article published on February 15, 2011

DOTA-functionalized polylysine: a high number of DOTA chelates positively influences the biodistribution of enzymatic conjugated anti-tumor antibody chCE7agl

scientific article

Design of Internalizing PSMA-specific Glu-ureido-based Radiotherapeuticals

scientific article

Detection of tumour progression in the follow-up of irradiated low-grade astrocytomas: comparison of 3-[123I]iodo-alpha-methyl- L-tyrosine and 99mTc-MIBI SPET.

scientific article published on 20 August 2002

Development and dosimetry of Pb/Pb-labelled PSMA ligands: bringing "the lead" into PSMA-targeted alpha therapy?

article

Development of Quinoline-Based Theranostic Ligands for the Targeting of Fibroblast Activation Protein

scientific article published on 06 April 2018

Diagnostic performance of 68Ga-PSMA-11 (HBED-CC) PET/CT in patients with recurrent prostate cancer: evaluation in 1007 patients

scientific article

Dosimetry estimate and initial clinical experience with Y-PSMA-617

article

Drug Conjugation Affects Pharmacokinetics and Specificity of Kidney-Targeted Peptide Carriers

scientific article published on 12 September 2016

Endoradiotherapy in cancer treatment--basic concepts and future trends

scientific article published on 15 October 2009

Endoradiotherapy with peptides - status and future development

scientific article

Engineering and Functionalization of the Disulfide‐Constrained Miniprotein Min‐23 as a Scaffold for Diagnostic Application ⬇️

scientific article published on December 23, 2011

Enzymes/transporters

scientific article published on January 2008

Erratum to: Diagnostic performance of 68Ga-PSMA-11 (HBED-CC) PET/CT in patients with recurrent prostate cancer: evaluation in 1007 patients.

scientific article

Erratum: Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scholarly article published in Nature Medicine

Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling

scientific article

Fine mapping of pre-S sequence requirements for hepatitis B virus large envelope protein-mediated receptor interaction

scientific article

Fluorescent somatostatin receptor probes for the intraoperative detection of tumor tissue with long-wavelength visible light

scientific article

GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth In Vitro and In Vivo ⬇️

scientific article published on August 31, 2012

Ga-FAPI PET/CT: Biodistribution and Preliminary Dosimetry Estimate of 2 DOTA-Containing FAP-Targeting Agents in Patients with Various Cancers

article

Gallium-68-DOTA-albumin as a PET blood-pool marker: experimental evaluation in vivo

scientific article published in April 2005

Generation of suppressive blood cells for control of allograft rejection

scientific article published in May 2015

Hepatic arterial infusion enhances DOTATOC radiopeptide therapy in patients with neuroendocrine liver metastases

scientific article published on 20 September 2011

Hepatitis B virus hepatotropism is mediated by specific receptor recognition in the liver and not restricted to susceptible hosts ⬇️

scientific article published on May 15, 2013

High treatment efficacy by dual targeting of Burkitt's lymphoma xenografted mice with a (177)Lu-based CD22-specific radioimmunoconjugate and rituximab.

scientific article published on 4 September 2015

Identification and characterization of a peptide with affinity to head and neck cancer

scientific article

Identification and evaluation of a new tumor cell-binding peptide, FROP-1.

scientific article

Identification of Ligands and Translation to Clinical Applications

scientific article published in September 2017

Identification of a Novel ITGαvβ6-Binding Peptide Using Protein Separation and Phage Display

scientific article

Identification of a new prostate-specific cyclic peptide with the bacterial FliTrx system

scientific article

Impact of functional genomics and proteomics on radionuclide imaging

scientific article published on January 2004

Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.

scientific article

Improving the Imaging Contrast of 68Ga-PSMA-11 by Targeted Linker Design: Charged Spacer Moieties Enhance the Pharmacokinetic Properties.

scientific article published on 8 August 2017

In vitro anticancer studies of alpha- and beta-D-glucopyranose betulin anomers

scientific article

Influence of chelate conjugation on a newly identified tumor-targeting peptide

scientific article

Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling.

scientific article published on 24 October 2015

Integration of CT urography improves diagnostic confidence of 68Ga-PSMA-11 PET/CT in prostate cancer patients

scientific article published on 20 December 2017

Intra-individual comparison of Tc-99m-MDP bone scan and the PSMA-ligand Tc-99m-MIP-1427 in patients with osseous metastasized prostate cancer

scientific article published on 25 January 2018

Is nano too big?

scientific article published on January 2014

Liver Imaging with a Novel Hepatitis B Surface Protein Derived SPECT-Tracer ⬇️

scientific article published on May 3, 2013

MIA (melanoma inhibitory activity) promoter mediated tissue-specific suicide gene therapy of malignant melanoma

scientific article published on June 2004

Mechanistic and high-throughput approaches for the design of molecular imaging probes and targeted therapeutics

Melanoma uptake of (99m)Tc complexes containing the N-(2-diethylaminoethyl)benzamide structural element

scientific article published in December 2002

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scientific article

Miniproteins as Phage Display-Scaffolds for Clinical Applications ⬇️

scientific article published on March 14, 2011

Multicyclic Peptides as Scaffolds for the Development of Tumor Targeting Agents

scientific article

Multimodal imaging for early functional response assessment of (90)Y-/ (177)Lu-DOTATOC peptide receptor targeted radiotherapy with DW-MRI and (68)Ga-DOTATOC-PET/CT.

scientific article published in August 2014

Multivalent cyclic RGD ligands: influence of linker lengths on receptor binding ⬇️

scientific article published on July 24, 2010

Myeloablative radioimmunotherapy in conditioning prior to haematological stem cell transplantation: closing the gap between benefit and toxicity?

scientific article published on 08 January 2009

Myristoylated PreS1-domain of the hepatitis B virus L-protein mediates specific binding to differentiated hepatocytes

scientific article

Optimization of a novel peptide ligand targeting human carbonic anhydrase IX

scientific article

Oral delivery of vancomycin by tetraether lipid liposomes.

scientific article published on 14 July 2017

PEGylation enables the specific tumor accumulation of a peptide identified by phage display

scientific article

PET and SPECT for detection of tumor progression in irradiated low-grade astrocytoma: a receiver-operating-characteristic analysis.

scientific article published in April 2004

PSMA-Targeted Radionuclide Therapy of Metastatic Castration-Resistant Prostate Cancer with 177Lu-Labeled PSMA-617.

scientific article published on 16 March 2016

Peptide-PNA conjugates: targeted transport of antisense therapeutics into tumors

scientific article published in April 2003

Peptide-based targeting of the platelet-derived growth factor receptor beta

scientific article

Pharmacokinetic Properties of Peptidic Radiopharmaceuticals: Reduced Uptake of (EH)3-Conjugates in Important Organs ⬇️

scientific article published on June 26, 2013

Pharmacological properties of hydrophilic and lipophilic derivatives of octreotate

scientific article published on January 2004

Phenomenon of Endothelial Antibody Capture: Principles and Potential for Locoregional Targeting of Hepatic Tumors

scientific article published on 21 September 2018

Polyamine-substituted gadolinium chelates: a new class of intracellular contrast agents for magnetic resonance imaging of tumors

scientific article published on January 2007

Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer.

scientific article published on 16 April 2015

Preclinical evaluation of a diabody-based (177)Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy in a non-Hodgkin lymphoma mouse model

scientific article published on 11 August 2016

Preclinical evaluation of the breast cancer cell-binding peptide, p160.

scientific article published on September 2005

Premature drug release of polymeric micelles and its effects on tumor targeting ⬇️

scientific article published on February 4, 2013

Pretreatment evaluation of carcinomas of the hypopharynx and larynx with 18F-fluorodeoxyglucose, 123I-alpha-methyl-L-tyrosine and 99mTc-hexakis-2-methoxyisobutylisonitrile.

scientific article

Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.

scientific article published on 24 February 2008

Radiation dosimetry and first therapy results with a (124)I/ (131)I-labeled small molecule (MIP-1095) targeting PSMA for prostate cancer therapy

scientific article published on 28 February 2014

Radioiodinated dechloro-4-iodofenofibrate: a hydrophobic model drug for molecular imaging studies.

scientific article

Radioiodine therapy of hepatoma using targeted transfer of the human sodium/iodide symporter gene.

scientific article published on May 2006

Radiolabeled peptides and proteins in cancer therapy

scientific article

Radiolabeling strategies for tumor-targeting proteinaceous drugs

scientific article published on 18 February 2014

Radionuclides in drug development

scientific article

Radiopharmaceutical therapy of patients with metastasized melanoma with the melanin-binding benzamide 131I-BA52.

scientific article

Rational design of CPP-based drug delivery systems: considerations from pharmacokinetics

scientific article

Renal Targeting: Peptide-Based Drug Delivery to Proximal Tubule Cells

scientific article published on 21 March 2016

Repeated Lu-177-PSMA-617 radioligand therapy using treatment activities up to 9.3 GBq.

scientific article published on 10 August 2017

Repeated PSMA-targeting radioligand therapy of metastatic prostate cancer with 131I-MIP-1095.

scientific article

Scintigraphic imaging of gene expression and gene transfer

scientific article

Screening of a novel peptide targeting the proteoglycan-like region of human carbonic anhydrase IX.

scientific article published on November 2013

Selective targeting of liver cancer with the endothelial marker CD146.

scientific article published in September 2014

Semi-automatic 3D-volumetry of liver metastases from neuroendocrine tumors to improve combination therapy with 177Lu-DOTATOC and 90Y-DOTATOC.

scientific article published on 22 March 2016

Solid-phase synthesis of the lipopeptide Myr-HBVpreS/2-78, a hepatitis B virus entry inhibitor.

scientific article published on 7 July 2010

Strategies for the treatment of HBV/HDV

scientific article published on 21 June 2018

Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals

scientific article

Synthesis and NMR characterization of hydroxyurea and mesylglycol glycoconjugates as drug candidates for targeted cancer chemotherapy

scientific article published in February 2005

Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography.

scientific article

Synthesis and evaluation of intercalating somatostatin receptor binding peptide conjugates for endoradiotherapy.

scientific article

Synthesis of Peptide Radiopharmaceuticals for the Therapy and Diagnosis of Tumor Diseases ⬇️

scientific article published on March 14, 2013

Targeting prostate cancer: Prostate-specific membrane antigen based diagnosis and therapy

scientific article published on 17 May 2018

Tetrafluorophenolate of HBED-CC: a versatile conjugation agent for 68Ga-labeled small recombinant antibodies

scientific article published on 29 May 2008

The Clinical Impact of Additional Late PET/CT Imaging with 68Ga-PSMA-11 (HBED-CC) in the Diagnosis of Prostate Cancer

scientific article published on 6 January 2017

The LepR-mediated leptin transport across brain barriers controls food reward

scientific article published on 7 December 2017

The Pharmacokinetics of Cell-Penetrating Peptides ⬇️

scientific article published on October 7, 2010

The Theranostic PSMA Ligand PSMA-617 in the Diagnosis of Prostate Cancer by PET/CT: Biodistribution in Humans, Radiation Dosimetry, and First Evaluation of Tumor Lesions.

scientific article published on 20 August 2015

The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis

scientific article

Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis

scientific article

Tracer uptake in mediastinal and paraaortal thoracic lymph nodes as a potential pitfall in image interpretation of PSMA ligand PET/CT

scientific article published on 01 March 2018

Troponin I overexpression inhibits tumor growth, perfusion, and vascularization of morris hepatoma.

scientific article published on September 2006

Tumor-specific gene expression using regulatory elements of the glucose transporter isoform 1 gene

scientific article published on January 2004

Ultra-sensitive and selective quantification of endothelin-1 in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry

scientific article published on 29 April 2017

[¹⁷⁷Lu]Lutetium-labelled PSMA ligand-induced remission in a patient with metastatic prostate cancer.

scientific article published on 9 January 2015

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