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List of works by Caroline Demangel

A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

article by Anne-Caroline Chany et al published 30 November 2011 in Chemistry—A European Journal

A novel mycolactone toxin obtained by biosynthetic engineering

scientific article

Apports de la génomique des mycobactéries a la définition de nouvelles stratégies thérapeutiques et vaccinales anti-tuberculeuses

Biologically active human anti-crotoxin scFv isolated from a semi-synthetic phage library ⬇️

scientific article published on June 1, 1997

Buruli ulcer disease: prospects for a vaccine

scientific article published on 07 February 2009

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

scientific article published on January 2009

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

article

CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy

scientific article published on 17 December 2019

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.

scientific article published on April 2004

Combined inflammatory and metabolic defects reflected by reduced serum protein levels in patients with Buruli ulcer disease

scientific article

Differential effects of prior exposure to environmental mycobacteria on vaccination with Mycobacterium bovis BCG or a recombinant BCG strain expressing RD1 antigens

scientific article

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

scientific article

Dysregulation of tryptophan catabolism at the host-skin microbiota interface in Hidradenitis Suppurativa

scientific article published on 24 September 2020

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

scientific article

Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

scientific article published on 11 December 2020

Entrapment of intracytosolic bacteria by septin cage-like structures

scientific article

Immunogenicity of Mycobacterium ulcerans Hsp65 and protective efficacy of a Mycobacterium leprae Hsp65-based DNA vaccine against Buruli ulcer

scientific article published on 24 May 2006

Immunosuppressive signature of cutaneous Mycobacterium ulcerans infection in the peripheral blood of patients with buruli ulcer disease

scientific article published in December 2009

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

scientific journal article

Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

scientific article published on 15 May 2019

Lactate dehydrogenase (LDH) activity of the cultured eukaryotic cells as marker of the number of dead cells in the medium [corrected]

scientific article published on September 1, 1992

Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease.

scientific article

Modular total syntheses of mycolactone A/B and its [2H]-isotopologue

article

Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin

scientific article published on August 2005

Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages

scientific article published on 19 January 2018

Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes

scientific article

Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation

scientific article published on 15 March 2013

Mycolactone diffuses from Mycobacterium ulcerans-infected tissues and targets mononuclear cells in peripheral blood and lymphoid organs

scientific article published in 2008

Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring

scientific article

Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

scientific article

Mycolactone subverts immunity by selectively blocking the Sec61 translocon.

scientific article

Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria

scientific article published on 17 April 2008

Pathogenesis of skin ulcers: lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens

scientific article published on 21 January 2014

Phage-displayed and soluble mouse scFv fragments neutralize rabies virus ⬇️

scientific article published on September 1, 1997

Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer.

scientific article published in June 2012

Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature

scientific article published on 18 June 2018

Recombinant Antibodies against Mycolactone

scientific article published on 17 June 2019

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

scientific article published on 14 April 2003

Sec61 blockade by mycolactone: A central mechanism in Buruli ulcer disease

scientific article published on 14 August 2018

Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

scientific article

Shaping mycolactone for therapeutic use against inflammatory disorders

scientific article published on May 2015

Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system

scientific article published on 02 December 2020

Synthetic Variants of Mycolactone Bind and Activate Wiskott–Aldrich Syndrome Proteins

The Sec61 translocon is a therapeutic vulnerability in multiple myeloma

scientific article published on 11 January 2022

Tuberculosis: from genome to vaccine

scientific article

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