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List of works by John V Fahy

A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic ⬇️

scientific article published on January 20, 2012

A Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity

scientific article

A Transcriptomic Method to Determine Airway Immune Dysfunction in T2-High and T2-Low Asthma

scientific article published on 01 February 2019

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production

scientific article

A role for neutrophils in asthma?

scientific article published in April 2002

A trial of clarithromycin for the treatment of suboptimally controlled asthma ⬇️

scientific article published on October 1, 2010

ALX receptor ligands define a biochemical endotype for severe asthma

scientific article

ALX receptor ligands define a biochemical endotype for severe asthma

scientific article published on 22 March 2018

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

scientific article

Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma

scientific article

Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma

scientific article

After asthma: redefining airways diseases.

scientific article published on 11 September 2017

Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids

scientific article

Alternative splicing of interleukin-33 and type 2 inflammation in asthma.

scientific article published on 18 July 2016

An Anti-Siglec-8 Antibody Depletes Sputum Eosinophils from Asthmatic Subjects and Inhibits Lung Mast Cells

scientific article published on 15 June 2020

Applying stereology to measure thickness of the basement membrane zone in bronchial biopsy specimens

scientific article published on 01 December 2003

Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program (SARP) III.

scientific article

Asthma Was Talking, But We Weren't Listening. Missed or Ignored Signals That Have Slowed Treatment Progress

scientific article published on March 2016

Asthma and corticosteroids: time for a more precise approach to treatment

scientific article

Asthma outcomes: biomarkers

scientific article

Asthma: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases

scientific article

Autopsy and Imaging Studies of Mucus in Asthma. Lessons Learned about Disease Mechanisms and the Role of Mucus in Airflow Obstruction

scientific article published on 01 November 2018

Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.

scientific article published on 30 August 2017

Baseline sputum eosinophil + neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) cohort

scientific article published on 05 February 2020

Binding of SARS-CoV-2 spike protein to ACE2 is disabled by thiol-based drugs; evidence from <i>in vitro</i> SARS-CoV-2 infection studies

scientific article published on 08 December 2020

COVID-19 Related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids

scientific article published on 29 April 2020

Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity

scientific article published on 13 February 2018

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

scientific article published on 17 September 2012

Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma

scientific article published on 20 April 2016

Clinical significance of the bronchodilator response in children with severe asthma

scientific article published on 19 August 2019

Cluster Analysis of Obesity and Asthma Phenotypes ⬇️

scientific article (publication date: 2012)

Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma

scientific article published on 14 September 2006

Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial

scientific article published on September 2012

Cross-Talk between Epithelial Cells and Type 2 Immune Signaling. The Role of IL-25.

scientific article published on May 2016

Daily versus as-needed corticosteroids for mild persistent asthma

scientific article published in April 2005

Development and initial validation of the Asthma Severity Scoring System (ASSESS)

scientific article published on 08 October 2019

Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial

scientific article

Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma

scientific article

Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.

scientific article

Effects of individual self-management education on clinical, biological, and adherence outcomes in asthma

scientific article published in December 2003

Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction

scientific article

Erratum: COVID-19-related Genes in Sputum Cells in Asthma: Relationship to Demographic Features and Corticosteroids

scientific article published on 01 December 2020

Estimated Ventricular Size, Asthma Severity, and Exacerbations: The Severe Asthma Research Program III Cohort

scientific article published on 12 September 2019

Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency

scientific article published on 01 June 2020

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

scientific article published on 01 May 2019

FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection

scientific article (publication date: April 2016)

Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways

scientific article published on 11 August 2020

Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression

scientific article

IL1RL1 asthma risk variants regulate airway type 2 inflammation

scientific article published on 08 September 2016

Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations

scientific article

Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma.

scientific article published on April 2014

Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control

scientific article published on 25 October 2017

Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma

scientific article published on 09 September 2019

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma.

scientific article published on 24 September 2013

Metabolic consequences of obesity as an "outside in" mechanism of disease severity in asthma.

scientific article published in August 2016

Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level

scientific article published on 19 May 2019

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers

scientific article published on 12 November 2020

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.

scientific article published on 5 February 2018

Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma

scientific article published on 01 June 2019

Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

scientific article published in March 2017

Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma

scientific article published on 01 August 2018

Oxidation increases mucin polymer cross-links to stiffen airway mucus gels

scientific article

P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy

scientific article published on 9 November 2012

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

scientific article published on August 2012

Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

scientific article

Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort

scientific article published on 01 July 2018

Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program

scientific article published on 08 January 2019

Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids

scientific article published on 7 March 2018

Reply to Nannini and Lipworth et al

scientific article published on 20 July 2020

Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate to Severe Asthma

scientific article published on 08 December 2020

Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease

scientific article

Severe asthma during childhood and adolescence: A longitudinal study

scientific article published on 14 October 2019

Significant variability in response to inhaled corticosteroids for persistent asthma

scientific article published in March 2002

Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma

scientific article published on 4 January 2007

Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids

scientific article

Systemic effect comparisons of six inhaled corticosteroid preparations

scientific article

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

scientific article published on 29 May 2009

The H Antigen at Epithelial Surfaces Is Associated with Susceptibility to Asthma Exacerbation ⬇️

scientific article published on August 23, 2010

The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial

scientific article

The Role of Type 2 Inflammation in the Pathogenesis of Asthma Exacerbations

scientific article

The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium.

scientific article published on 18 April 2019

The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations

scientific article published on 17 September 2020

The role of mucus in fatal asthma

scientific article published on 01 July 2003

The use of hydrophobic amino acids in protecting spray dried trehalose formulations against moisture-induced changes

scientific article published on 16 September 2019

Tiotropium bromide step-up therapy for adults with uncontrolled asthma

scientific article

Type 2 immune responses in obese individuals with asthma.

scientific article published in September 2013

Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

scientific article published in October 2004

beta-Adrenergic receptor polymorphisms and response to salmeterol

scientific article published on December 2005

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