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List of works by Warren D Shlomchik

A Crucial Role for Host APCs in the Induction of Donor CD4+CD25+ Regulatory T Cell-Mediated Suppression of Experimental Graft-versus-Host Disease ⬇️

scientific article published on October 1, 2010

A repertoire-independent and cell-intrinsic defect in murine GVHD induction by effector memory T cells

scientific article published on 18 July 2011

APCs in the liver and spleen recruit activated allogeneic CD8+ T cells to elicit hepatic graft-versus-host disease

scientific article published in December 2002

An innate response to allogeneic nonself mediated by monocytes

scientific article published in December 2009

Antigen presentation in graft-vs-host disease

scientific article published on December 2003

Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells

scientific article

Biology of graft-versus-host responses: recent insights

scientific article published on January 2013

CD45 ligation expands Tregs by promoting interactions with DCs

scientific article

CD8+ but not CD4+ T cells require cognate interactions with target tissues to mediate GVHD across only minor H antigens, whereas both CD4+ and CD8+ T cells require direct leukemic contact to mediate GVL.

scientific article published on 25 January 2008

Central memory CD8+ T cells induce graft-versus-host disease and mediate graft-versus-leukemia

scientific article published in May 2009

Characterization of a novel gain of function glucocorticoid receptor knock-in mouse

scientific article

Cognate antigen directs CD8+ T cell migration to vascularized transplants

scientific article

Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity

scientific article published on 12 June 2017

Donor APCs are required for maximal GVHD but not for GVL

scientific article published on 01 August 2004

Donor SIRPα polymorphism modulates the innate immune response to allogeneic grafts.

scientific article published on June 2017

Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

scientific article (publication date: 15 March 2002)

Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host disease

scientific article published on 28 November 2007

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

scientific article published on 19 February 2008

Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells

scientific article

Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4+ effector memory T cells ⬇️

scientific article published on August 18, 2011

Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity

scientific article

GVL against murine chronic phase and blast phase CML.

scientific article published in January 2008

Graft-Versus-Host-Disease Recruits Both Monocyte and Pre-Conventional Dendritic Cell-Derived Tissue Antigen Presenting Cells Independent Of CCR2 and CCR6 ⬇️

scholarly article

Graft-infiltrating host dendritic cells play a key role in organ transplant rejection

scientific article

Graft-versus-host disease

scientific article published on May 2007

Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells ⬇️

scientific article published on November 22, 2010

Graft-versus-leukemia (GVL) against mouse blast-crisis chronic myelogenous leukemia (BC-CML) and chronic-phase chronic myelogenous leukemia (CP-CML): shared mechanisms of T cell killing, but programmed death ligands render CP-CML and not BC-CML GVL

scientific article published on July 18, 2011

Graft-versus-leukemia in a retrovirally induced murine CML model: mechanisms of T-cell killing

scientific article published on 24 February 2004

In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease

scientific article published on 01 July 2019

Innate immunity alone is not sufficient for chronic rejection but predisposes healed allografts to T cell-mediated pathology ⬇️

scientific article published on December 24, 2011

Langerhans cells are not required for efficient skin graft rejection

scientific article published on 13 March 2008

Langerhans cells are not required for graft-versus-host disease ⬇️

scientific article published on October 13, 2010

Leukemia-Specific Antigens Alone Are Insufficient for GVL in MHC-Matched Allogeneic Stem Cell Transplantation: An Essential Role for Minor H Antigens. ⬇️

scholarly article

Mechanisms of GVL Against a Murine Blast Crisis CML. ⬇️

scholarly article

Mechanisms of antigen presentation to T cells in murine graft-versus-host disease: cross-presentation and the appearance of cross-presentation ⬇️

scientific article published on September 30, 2011

Memory CD4+ T cells do not induce graft-versus-host disease

scientific article

Memory CD8. + T Cells Specific for Minor Histocompatibility Antigen H60 Can Mediate the Graft-Versus-Leukemia Effect. ⬇️

scholarly article

Memory T cells from minor histocompatibility antigen–vaccinated and virus-immune donors improve GVL and immune reconstitution ⬇️

scientific article published on September 13, 2011

Memory T cells in GVHD and GVL.

scientific article published on January 2008

MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

scientific article

NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells

scientific article published on 14 May 2010

Non-self recognition by monocytes initiates allograft rejection

scientific article

Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts

scientific article

PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-versus-Host Disease

scientific article

Profound Depletion of Host Conventional Dendritic Cells, Plasmacytoid Dendritic Cells, and B Cells Does Not Prevent Graft-versus-Host Disease Induction ⬇️

scientific article published on March 14, 2012

Recipient B cells are not required for graft-versus-host disease induction

scientific article

Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host disease

scientific article published on 18 May 2004

Regulatory T Cells Require Mammalian Target of Rapamycin Signaling To Maintain Both Homeostasis and Alloantigen-Driven Proliferation in Lymphocyte-Replete Mice ⬇️

scientific article published on January 26, 2011

Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.

scientific article published on 22 February 2016

T cell exhaustion and a failure in antigen presentation drive resistance to the graft-versus-leukemia effect

scientific article published on 24 August 2020

Target antigens determine graft-versus-host disease phenotype

scientific article published on 01 November 2004

Tissue-resident memory T cell maintenance during antigen persistence requires both cognate antigen and interleukin-15

scientific article published on 21 April 2023

Transplantation's greatest challenges: advances in chronic graft-versus-host disease

scientific article published on January 2007

Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease

scientific article published on 4 April 2017

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