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List of works by Randal J Kaufman

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

scientific article

Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line

scientific article published on December 1981

Amplification of Dihydrofolate Reductase Genes in Methotrexate-resistant Cultured Mouse Cells ⬇️

scientific article published on January 1, 1978

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line ⬇️

scientific article published on November 1, 1978

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes ⬇️

scientific article published on November 1, 1979

Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression

scientific article published on December 2005

Biosynthesis, structure, and folding of the insulin precursor protein

scientific article published on 01 September 2018

Chromosomal and extrachromosomal localization of amplified dihydrofolate reductase genes in cultured mammalian cells.

scientific article

Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells ⬇️

scientific article published on November 1, 1979

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

scientific article

Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma.

scientific article

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

scientific article published on 8 September 2005

Expression of murine ADA cDNA in bacterial and mammalian cells.

scientific article published in January 1986

Gene amplification and drug resistance in cultured murine cells

scientific article published in December 1978

Gene amplification and drug resistance in mammalian cells.

scientific article

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

scientific article

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 mice

scientific article published on 02 April 2019

IRE1α nucleotide sequence cleavage specificity in the unfolded protein response.

scientific article

IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs.

scientific article published on 15 May 2018

Identification of functional murine adenosine deaminase cDNA clones by complementation in Escherichia coli.

scientific article

Initiation of protein synthesis in bacteria at a translational start codon of mamalian cDNA: effects of the preceding nucleotide sequence ⬇️

scientific article published on March 1, 1980

Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines

scientific article published on December 1981

Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

scientific article

Maternal immune activation in mice disrupts proteostasis in the fetal brain

scientific article published on 23 December 2020

Mechanisms, regulation and functions of the unfolded protein response

scientific article published on 26 May 2020

Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca

scientific article published on 09 September 2019

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

scientific article published on 20 May 2019

Novel function of PERK as a mediator of force-induced apoptosis

scientific article published on 11 June 2008

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.

scientific article published on 11 June 2019

Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase ⬇️

scientific article published on October 19, 1978

Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase. 1978

scientific article published on January 1, 1992

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development

scholarly article

Proinsulin misfolding is an early event in the progression to type 2 diabetes.

scientific article published on 11 June 2019

Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

scientific article published on 01 July 2019

Quantitation of dihydrofolate reductase in individual parental and methotrexate-resistant murine cells. Use of a fluorescence activated cell sorter ⬇️

scientific article published on August 25, 1978

Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells

scientific article published on May 1986

Structure and genomic organization of the mouse dihydrofolate reductase gene ⬇️

scientific article published on February 1, 1980

Studies on the Amplification of Dihydrofolate Reductase Genes in Methotrexate-resistant Cultured Mouse Cells ⬇️

scientific article published on January 1, 1979

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

scientific article

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

scientific article published on December 2004

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR

article

eIF2α controls memory consolidation via excitatory and somatostatin neurons

scientific article published on 07 October 2020

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