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List of works by Richard H Karas

17-beta-estradiol increases cardiac remodeling and mortality in mice with myocardial infarction

scientific article

A novel mechanism for the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced vasorelaxation and increased endothelial nitric oxide synthase expression

scientific article published in July 2002

Abdominal Positioning of the Next-Generation Intra-Aortic Fluid Entrainment Pump (Aortix) Improves Cardiac Output in a Swine Model of Heart Failure

Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta

scientific article published in January 2002

Acute Hemodynamic Effects of Intra-aortic Balloon Counterpulsation Pumps in Advanced Heart Failure

scientific article published on 26 May 2017

Adverse events with concomitant amiodarone and statin therapy

scientific article published in January 2005

Adverse events with concomitant use of simvastatin or atorvastatin and thiazolidinediones

scientific article

Assessment of peripheral vascular endothelial function in the ambulatory setting

scientific article published in February 2007

Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude.

scientific article published on July 2003

Assessment of vascular endothelial function with peripheral arterial tonometry: information at your fingertips?

scientific article published on January 2010

Augmentation Index Derived from Peripheral Arterial Tonometry Correlates with Cardiovascular Risk Factors ⬇️

scientific article published on July 9, 2011

Baseline and on-treatment high-density lipoprotein cholesterol and the risk of cancer in randomized controlled trials of lipid-altering therapy

scientific article published on June 2010

Bidirectional regulation of angiogenesis by phytoestrogens through estrogen receptor-mediated signaling networks

scientific article published on 01 April 2016

Bone Morphogenetic Protein 9 Reduces Cardiac Fibrosis and Improves Cardiac Function in Heart Failure

scientific article published on 27 February 2018

Clinical utility of endothelial function testing: ready for prime time?

scientific article

Comparison of flow-mediated dilatation of the brachial artery in coronary patients with low-density lipoprotein cholesterol levels <80 mg/dl versus patients with levels 80 to 100 mg/dl.

scientific article published in January 2005

Comparison of the frequency of adverse events in patients treated with atorvastatin or simvastatin

scientific article published in April 2003

Conditional knockout of activin like kinase-1 (ALK-1) leads to heart failure without maladaptive remodeling

scientific article published on 17 February 2017

Differential effects of statins (pravastatin or simvastatin) on ventricular ectopic complexes: Galpha(i2), a possible molecular marker for ventricular irritability

scientific article published on 20 February 2010

Differential regulation of the inducible nitric oxide synthase gene by estrogen receptors 1 and 2

scientific article published on 27 August 2008

Effect of Atenolol vs Metoprolol Succinate on Vascular Function in Patients With Hypertension ⬇️

scientific article published on January 1, 2011

Effect of short-term antibiotic treatment on Chlamydia pneumoniae and peripheral endothelial function.

scientific article published on March 2003

Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials

scientific article

Effects of estrogen on cardiac electrophysiology in female mice

scientific article published on March 2002

Effects of extended-release niacin on lipoprotein particle size, distribution, and inflammatory markers in patients with coronary artery disease.

scientific article published on 26 July 2006

Elevated Soluble fms-Like Tyrosine Kinase-1 Levels in Acute Coronary Occlusion ⬇️

scientific article published on November 11, 2010

Elevated augmentation index derived from peripheral arterial tonometry is associated with abnormal ventricular-vascular coupling

scientific article

Endoglin selectively modulates transient receptor potential channel expression in left and right heart failure

scientific article published on 21 August 2016

Endothelial function and soluble endoglin in smokers with heart failure

scientific article published on 28 November 2011

Endothelial progenitor cells delivered into the pericardial space incorporate into areas of ischemic myocardium ⬇️

scientific article published on October 1, 2010

Endothelium-dependent vasodilation is associated with exercise capacity in smokers and non-smokers

scientific article

Estrogen Receptor-α Non-Nuclear Signaling Confers Cardioprotection and Is Essential to cGMP-PDE5 Inhibition Efficacy

scientific article published on 04 March 2020

Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury

scientific article published in May 2002

Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species

scientific article published on 20 March 2007

Evaluation of peripheral vascular endothelial function with a portable ultrasound device

scientific article published in September 2006

Extended-release niacin reduces LDL particle number without changing total LDL cholesterol in patients with stable CAD ⬇️

scientific article published on December 13, 2008

Extent to which accepted serum lipid goals are achieved in a contemporary general medical population with coronary heart disease risk equivalents

scientific article published on 7 September 2006

Ezetimibe, and the combination of ezetimibe/simvastatin, and risk of cancer: A post-marketing analysis ⬇️

scientific article published on February 11, 2009

First-in-human experience with occlusion of the superior vena cava to reduce cardiac filling pressures in congestive heart failure

scientific article published on 21 May 2019

Gender-based differences in brachial artery flow-mediated vasodilation as an indicator of significant coronary artery disease

scientific article published on 02 September 2005

Hemodynamic effects of left atrial or left ventricular cannulation for acute circulatory support in a bovine model of left heart injury

scientific article published on 01 May 2015

High-density lipoprotein cholesterol and coronary heart disease

scientific article published on March 2004

High-density lipoprotein cholesterol in the cardiovascular equation: does the "good" still count?

scientific article

High-density lipoprotein cholesterol-raising strategies

scientific article

High-density lipoprotein increases the abundance of eNOS protein in human vascular endothelial cells by increasing its half-life

scientific article

Identification of protein kinase G I alpha interacting proteins as potential targets to prevent cardiac remodeling

scientific article published on 29 August 2013

Intermittent Occlusion of the Superior Vena Cava Reduces Cardiac Filling Pressures in Preclinical Models of Heart Failure

scientific article published on 26 November 2019

Left Ventricular Unloading Before Reperfusion Promotes Functional Recovery After Acute Myocardial Infarction

scientific article published on 01 July 2018

MAP kinase mediates growth factor-induced nuclear translocation of estrogen receptor alpha

scientific article

Mechanically unloading the left ventricle before coronary reperfusion reduces left ventricular wall stress and myocardial infarct size

scientific article published on 13 June 2013

Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A

scientific article published on 15 May 2018

Meta-analysis: Statin Therapy Does Not Alter the Association Between Low Levels of High-Density Lipoprotein Cholesterol and Increased Cardiovascular Risk ⬇️

scientific article published on December 21, 2010

Mixed Lineage Kinase 3 (MLK3) Prevents Cardiac Dysfunction and Structural Remodeling with Pressure Overload

article

Modestly overweight women have vascular endothelial dysfunction

scientific article published on 01 May 2009

Molecular and cellular basis of cardiovascular gender differences

scientific article

Mutation of the Protein Kinase I Alpha Leucine Zipper Domain Produces Hypertension and Progressive Left Ventricular Hypertrophy: A Novel Mouse Model of Age-Dependent Hypertensive Heart Disease ⬇️

scientific article published on 08 May 2013

Niacin's role in the statin era.

scientific article published on October 2010

Nonoptimal high-density lipoprotein cholesterol levels are highly prevalent in patients presenting with acute coronary syndromes and well-controlled low-density lipoprotein cholesterol levels ⬇️

scientific article published on April 24, 2010

Peripheral Augmentation Index is Associated With the Ambulatory Arterial Stiffness Index in Patients With Hypertension.

scientific article published on 20 September 2011

Peripheral arterial tonometry for risk stratification in men with coronary artery disease

scientific article

Peripheral augmentation index and vascular inflammation in autosomal dominant polycystic kidney disease ⬇️

scientific article published on February 3, 2011

Peripheral augmentation index as a biomarker of vascular aging: an invasive hemodynamics approach ⬇️

scientific article published on December 3, 2011

Peripheral vascular endothelial function correlates with exercise capacity in cardiac transplant recipients

scientific article

Peripheral vascular endothelial function correlates with exercise capacity in women

scientific article published on 01 September 2005

Peripheral vascular endothelial function in patients with hypertrophic cardiomyopathy.

scientific article

Present-day uses of niacin: effects on lipid and non-lipid parameters

scientific article published on August 2007

Prevalence of low high-density lipoprotein cholesterol in patients with documented coronary heart disease or risk equivalent and controlled low-density lipoprotein cholesterol

scientific article published on 27 September 2007

Protein Kinase G Iα Inhibits Pressure Overload–Induced Cardiac Remodeling and Is Required for the Cardioprotective Effect of Sildenafil In Vivo ⬇️

scientific article published on October 25, 2012

Protein kinase G I alpha activates an anti-remodeling signaling pathway in the heart via an interaction with the MAPKKK mixed lineage kinase 3.

scientific article published in August 2011

Pulse wave amplitude is associated with brachial artery diameter: implications for gender differences in microvascular function

scientific article

Racial differences in central hemodynamic burden in men with HIV: preliminary findings

scientific article published on January 2013

Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury.

scientific article published on 20 September 2012

Reduced Endoglin Activity Limits Cardiac Fibrosis and Improves Survival in Heart Failure ⬇️

scientific article published on May 16, 2012

Reduced activin receptor-like kinase 1 activity promotes cardiac fibrosis in heart failure

scientific article published on 18 July 2017

Regulation of estrogen receptor alpha-mediated transcription by a direct interaction with protein phosphatase 2A.

scientific article published on 3 December 2002

Relation between high-density lipoprotein cholesterol and peripheral vasomotor function.

scientific article published in August 2003

Relation of pulse pressure to blood pressure response to exercise in patients with hypertrophic cardiomyopathy

scientific article

Relative safety of gemfibrozil and fenofibrate in the absence of concomitant cerivastatin use.

scientific article published on 26 November 2007

Right Ventricular Dysfunction in Acute Myocardial Infarction Complicated by Cardiogenic Shock: A Hemodynamic Analysis of the Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock (SHOCK) Trial and Registry

scientific article published on 11 October 2017

Risk of adverse events with concomitant use of atorvastatin or simvastatin and glucose-lowering drugs (thiazolidinediones, metformin, sulfonylurea, insulin, and acarbose).

scientific article published in June 2002

Risk of adverse events with fibrates

scientific article published in October 2004

Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system)

scientific article published on 08 December 2006

Smooth muscle cell specific deletion of the PKGIα target RGS2 induces vascular dysfunction and hypertension.

scientific article published in August 2011

Statins, low-density lipoprotein cholesterol, and risk of cancer

scientific article published in September 2008

Tendon rupture associated with simvastatin/ezetimibe therapy

scientific article published on 21 May 2007

The relationship of statins to rhabdomyolysis, malignancy, and hepatic toxicity: evidence from clinical trials

scientific article

The safety of niacin in the US Food and Drug Administration adverse event reporting database

scientific article published on April 2008

The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis

scientific article published on 23 May 2005

Transvalvular Ventricular Unloading Before Reperfusion in Acute Myocardial Infarction

scientific article published on 01 August 2020

Unliganded estrogen receptor alpha regulates vascular cell function and gene expression

scientific article published on 22 November 2016

Unloading the Left Ventricle Before Reperfusion in Patients With Anterior ST-Segment-Elevation Myocardial Infarction

scientific article published on 01 January 2019

Usefulness of Soluble Endoglin as a Noninvasive Measure of Left Ventricular Filling Pressure in Heart Failure ⬇️

scientific article published on December 15, 2010

Vascular endothelial dysfunction is associated with reversible myocardial perfusion defects in the absence of obstructive coronary artery disease.

scientific article published in November 2006

Ventricular assist device therapy normalizes inducible nitric oxide synthase expression and reduces cardiomyocyte apoptosis in the failing human heart

scientific article published in May 2005

p38 mitogen-activated protein kinase activates eNOS in endothelial cells by an estrogen receptor alpha-dependent pathway in response to black tea polyphenols.

scientific article

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