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List of works by Steven P. Gygi

A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain.

scientific article

A High-Throughput, Multiplexed Kinase Assay Using a Benchtop Orbitrap Mass Spectrometer To Investigate the Effect of Kinase Inhibitors on Kinase Signaling Pathways ⬇️

scientific article published on July 3, 2012

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

scientific journal article

A Perturbed Ubiquitin Landscape Distinguishes Between Ubiquitin in Trafficking and in Proteolysis ⬇️

scientific article published on March 22, 2011

A Proteomic Strategy for Gaining Insights into Protein Sumoylation in Yeast

scientific article published on 12 November 2004

A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development

scientific article

A Strategy to Combine Sample Multiplexing with Targeted Proteomics Assays for High-Throughput Protein Signature Characterization

scientific article published on 21 December 2016

A Triple Knockout (TKO) Proteomics Standard for Diagnosing Ion Interference in Isobaric Labeling Experiments

scientific article published on 11 July 2016

A Triple Knockout Isobaric-Labeling Quality Control Platform with an Integrated Online Database Search

scientific article published on 27 March 2020

A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway

scientific article

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

scientific article

A comparative proteomic analysis of human and rat embryonic cerebrospinal fluid.

scientific article published on 16 August 2007

A comprehensive proteomic and phosphoproteomic analysis of yeast deletion mutants of 14-3-3 orthologs and associated effects of rapamycin

scientific article published on 17 December 2014

A conserved CCCH-type zinc finger protein regulates mRNA nuclear adenylation and export

scientific article

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

scientific article

A conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast. ⬇️

scientific article published on 9 August 2017

A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2α phosphorylation in obesity

scientific article published on 2 April 2015

A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation

scientific article published on 30 July 2005

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

scientific article

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability

scientific article

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex

scientific article

A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics

scientific article published on 03 May 2021

A large-scale method to measure absolute protein phosphorylation stoichiometries

scientific article published on 3 July 2011

A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides

scientific article published on 15 June 2015

A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans

scientific article

A molecular determinant for the establishment of sister chromatid cohesion

scientific article published in July 2008

A multi-parametric flow cytometric assay to analyze DNA-protein interactions.

scientific article published on 11 November 2012

A multi-scale map of cell structure fusing protein images and interactions

scientific article published on 24 November 2021

A phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast

scientific article

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

scientific article

A protein complex network of Drosophila melanogaster

scientific article published in October 2011

A proteomics approach to understanding protein ubiquitination

scientific article (publication date: August 2003)

A quantitative atlas of mitotic phosphorylation

scientific article

A quantitative proteomic analysis of growth factor-induced compositional changes in lipid rafts of human smooth muscle cells

article

A site-specific, multiplexed kinase activity assay using stable-isotope dilution and high-resolution mass spectrometry

scientific article

A solid phase extraction-based platform for rapid phosphoproteomic analysis

scientific article

A stress-responsive system for mitochondrial protein degradation

scientific article

A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery

scientific article published on 13 October 2003

A tissue-specific atlas of mouse protein phosphorylation and expression

scientific article (publication date: 23 December 2010)

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

scientific article published on 29 January 2012

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

scientific article

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex

scientific article published on 15 September 2010

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

scientific article

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

scientific article

Absence of Diabetes and Pancreatic Exocrine Dysfunction in a Transgenic Model of Carboxyl-Ester Lipase-MODY (Maturity-Onset Diabetes of the Young) ⬇️

scientific article published on April 2, 2013

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

scientific article

Accurate multiplexed proteomics at the MS2 level using the complement reporter ion cluster.

scientific article published on 25 October 2012

Acetylation-dependent regulation of Skp2 function

scientific article

Activated Inositol 1,4,5-Trisphosphate Receptors Are Modified by Homogeneous Lys-48- and Lys-63-linked Ubiquitin Chains, but Only Lys-48-linked Chains Are Required for Degradation ⬇️

scientific article published on November 11, 2010

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

scientific article

Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes

scientific article

Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases

scientific article published on 24 August 2010

Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins

scientific article

Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.

scientific article

Aminoglycoside-driven biosynthesis of selenium-deficient Selenoprotein P.

scientific article

Amyloid-like Self-Assembly of a Cellular Compartment

scientific article published on July 2016

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

scientific article published on 27 September 2007

An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer

scientific article published on December 2016

An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ.

scientific article

An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex

scientific article

An OBSL1-Cul7Fbxw8 Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning ⬇️

scientific article published on May 10, 2011

An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis

scientific article

An asymmetric interface between the regulatory and core particles of the proteasome

scientific article

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons

scientific article published on 26 September 2017

An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets

scientific article

Angiogenin-induced tRNA fragments inhibit translation initiation

scientific article

Assessing enzyme activities using stable isotope labeling and mass spectrometry

scientific article

Assigning spectrum-specific P-values to protein identifications by mass spectrometry

scientific article

Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation

scientific article

Automation of nanoscale microcapillary liquid chromatography-tandem mass spectrometry with a vented column

scientific article

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates

scientific article

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

scientific journal article

BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number

scientific article published on October 2004

Benchmarking the Orbitrap Tribrid Eclipse for Next Generation Multiplexed Proteomics

scientific article published on 06 April 2020

Blood biomarkers in a mouse model of CADASIL.

scientific article

Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions.

scientific article

C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress

scientific article (publication date: September 2012)

CD22 is a functional ligand for SH2 domain-containing protein-tyrosine phosphatase-1 in primary T cells

scientific article

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival ⬇️

scientific article (publication date: 6 February 2004)

Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid

scientific article published on 23 September 2013

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

scholarly article by Elahu G. Sustarsic published in July 2018

Catch-and-release reagents for broadscale quantitative proteomics analyses

scientific article published on 21 February 2007

Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis

scientific journal article

Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex.

scientific article published on 23 January 2014

Cdc28-dependent regulation of the Cdc5/Polo kinase

scientific article

Cdc7-Dbf4 Is a Gene-Specific Regulator of Meiotic Transcription in Yeast ⬇️

scientific article published on November 21, 2011

Cdk1 coordinates cell-surface growth with the cell cycle.

scientific article

Cdk1-dependent regulation of the mitotic inhibitor Wee1.

scientific article

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

scientific article

Cellular spelunking: exploring adipocyte caveolae

scientific article published on 11 May 2007

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

scientific article

Changes in cell morphology are coordinated with cell growth through the TORC1 pathway

scientific article published on 27 June 2013

Chaperone-mediated pathway of proteasome regulatory particle assembly

scientific article

Characterization of Plasmodium falciparum Atypical Kinase PfPK7- Dependent Phosphoproteome

scientific article published on 20 April 2018

Characterization of mouse spleen cells by subtractive proteomics

scientific article published on 21 July 2005

Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation

scientific article

Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis

scientific article

Cold Temperature Induces the Reprogramming of Proteolytic Pathways in Yeast.

scientific article published on 24 November 2015

Combining amine metabolomics and quantitative proteomics of cancer cells using derivatization with isobaric tags

scientific article published on 20 March 2014

Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos

scientific article

Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations

scientific article

Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae

scientific article published in April 2002

Comprehensive Temporal Protein Dynamics during the Diauxic Shift in Saccharomyces cerevisiae

scientific article

Comprehensive proteomic analysis of the human spliceosome

scientific article (publication date: 12 September 2002)

Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin

scientific article

Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation

scientific article published on 10 February 2017

Cooperative interaction between phosphorylation sites on PERIOD maintains circadian period in Drosophila

scientific article (publication date: 2013)

Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes

scientific article published on 7 May 2011

Correction to Characterization and Optimization of Multiplexed Quantitative Analyses Using High-Field Asymmetric-Waveform Ion Mobility Mass Spectrometry

scientific article published on 05 March 2020

Correction: Prokaryotic Ubiquitin-Like Protein (Pup) Proteome of Mycobacterium tuberculosis

scientific article published on 29 July 2010

Correlation profiling for determining kinase-substrate relationships ⬇️

scientific article published on March 21, 2013

Cuz1/Ynl155w, a zinc-dependent ubiquitin-binding protein, protects cells from metalloid-induced proteotoxicity

scientific article

DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation

scientific article published on 17 March 2021

DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells

scientific article

Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database

scientific article

Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice

article published in the Proceedings of the National Academy of Sciences of the United States of America

Defining the consequences of genetic variation on a proteome-wide scale.

scientific article published on 15 June 2016

Defining the human deubiquitinating enzyme interaction landscape

scientific article

Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site

scientific article

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

scientific article

Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

scientific article

Development of a Multiplexed Microcapillary Liquid Chromatography System for High-Throughput Proteome Analysis

article

Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells

scientific article

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

scientific journal article

Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

scientific article published on August 2011

Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia

scientific article published on 01 March 2021

Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging

scientific article

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

scientific article published on 08 June 2009

Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics ⬇️

scientific article published on December 10, 2010

ERRα Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-Elevated Melanomas

scientific article published on 8 June 2017

Effects of MEK inhibitors GSK1120212 and PD0325901 in vivo using 10-plex quantitative proteomics and phosphoproteomics

scientific article published on 18 October 2014

Endocytosis of Ubiquitylation-Deficient EGFR Mutants via Clathrin-Coated Pits is Mediated by Ubiquitylation

scientific article published on 7 August 2015

Erratum: A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides

scientific article published on 01 August 2015

Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite

scholarly article published 2018

Evaluating False Transfer Rates from the Match-between-Runs Algorithm with a Two-Proteome Model

scientific article published on 02 October 2019

Evaluating multiplexed quantitative phosphopeptide analysis on a hybrid quadrupole mass filter/linear ion trap/orbitrap mass spectrometer

scientific article

Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.

scientific article published on 13 September 2011

Evaluation of the utility of neutral-loss-dependent MS3 strategies in large-scale phosphorylation analysis

scientific article published on November 2008

Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients

scientific article published on June 2017

Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.

scientific article

Fat cells directly sense temperature to activate thermogenesis ⬇️

scientific article published on July 23, 2013

Filter-based Protein Digestion (FPD): A Detergent-free and Scaffold-based Strategy for TMT workflows.

scientific article

Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast

scientific article published on 11 July 2008

Follistatin-like 3 (FSTL3) mediated silencing of transforming growth factor β (TGFβ) signaling is essential for testicular aging and regulating testis size

scientific article published on 13 February 2013

Full-Featured, Real-Time Database Searching Platform Enables Fast and Accurate Multiplexed Quantitative Proteomics

scientific article published on 06 April 2020

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

scientific article

GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation

scientific article published on 02 June 2009

Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility

scientific journal article

Gas-phase rearrangements do not affect site localization reliability in phosphoproteomics data sets

scientific article

Generation of multiple reporter ions from a single isobaric reagent increases multiplexing capacity for quantitative proteomics.

scientific article published on 26 August 2015

Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia ⬇️

scientific article published on October 29, 2012

Global Analysis of Protein Expression and Phosphorylation Levels in Nicotine-Treated Pancreatic Stellate Cells

scientific article published on 11 August 2015

Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic development.

scientific article published on 26 August 2013

Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).

scientific article

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

scientific article (publication date: 14 December 2007)

HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms

scientific article published on December 2008

HYpro16: A Two-Proteome Mixture to Assess Interference in Isobaric Tag-Based Sample Multiplexing Experiments

scientific article published on 11 November 2020

Haptoglobin-alpha subunit as potential serum biomarker in ovarian cancer: identification and characterization using proteomic profiling and mass spectrometry.

scientific article

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

scientific article

Heterochromatic Gene Silencing by Activator Interference and a Transcription Elongation Barrier ⬇️

scientific article published on August 12, 2013

High error rates in selenocysteine insertion in mammalian cells treated with the antibiotic doxycycline, chloramphenicol, or geneticin

scientific article published on 15 April 2013

Host resistance to lung infection mediated by major vault protein in epithelial cells

scientific article

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

scientific article

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways

scientific article

Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response to rapamycin in yeast

scientific article published on 27 March 2012

Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease

scientific article

Identification of 14-3-3epsilon substrates from embryonic murine brain

scientific article published in September 2006

Identification of FBXO25-interacting proteins using an integrated proteomics approach

scientific article

Identification of Protein Components ininvivoHuman Acquired Enamel Pellicle Using LC−ESI−MS/MS

scientific article published on 21 April 2007

Identification of a protein mediating respiratory supercomplex stability

scientific article

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

scientific article

Identification of aneuploidy-tolerating mutations

scientific article

Identification of beta-secretase (BACE1) substrates using quantitative proteomics

scientific article

Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding

scientific article

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

scientific article

Improved Monoisotopic Mass Estimation for Deeper Proteome Coverage

scientific article published on 16 November 2020

In situ observation of protein phosphorylation by high-resolution NMR spectroscopy

scientific article

Increasing Throughput in Targeted Proteomics Assays: 54-Plex Quantitation in a Single Mass Spectrometry Run ⬇️

scientific article published on May 23, 2013

Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses

scientific article published on 20 August 2012

Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer

scientific article

Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex

scientific article

Intensity-based protein identification by machine learning from a library of tandem mass spectra.

scientific article

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

scientific article published on 8 June 2018

Intramolecular interactions control Vms1 translocation to damaged mitochondria

scientific article

Isobaric Tag-Based Protein Profiling of a Nicotine-Treated Alpha7 Nicotinic Receptor-Null Human Haploid Cell Line

scientific article published on 16 April 2018

Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins

scientific article published on March 2009

LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency

scientific article published on 19 December 2016

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

scientific article (publication date: 18 April 2013)

Large-scale characterization of HeLa cell nuclear phosphoproteins

scientific article

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain

scientific article published on 23 November 2007

Large-scale phosphorylation analysis of mouse liver

scholarly article

Large-scale proteomic characterization of melanoma expressed proteins reveals nestin and vimentin as biomarkers that can potentially distinguish melanoma subtypes

scientific article published on 16 October 2014

Latency-associated degradation of the MRP1 drug transporter during latent human cytomegalovirus infection

scientific article published on April 2013

Lysine 63-linked polyubiquitination is required for EGF receptor degradation

scientific article published on 09 September 2013

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

scientific article published on November 2007

MEKK2 mediates an alternative β-catenin pathway that promotes bone formation

scientific article published on 16 February 2016

METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction.

scientific article published on July 2015

MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice

scientific article

MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics

scientific article

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

scientific article

Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion ⬇️

scientific article published on May 2015

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

scientific article

Mapping and analysis of phosphorylation sites: a quick guide for cell biologists

scientific article

Mass spectrometric analysis of the editosome and other multiprotein complexes in Trypanosoma brucei.

scientific article published in July 2003

Mechanism of group IVA cytosolic phospholipase A(2) activation by phosphorylation

scientific article published on 28 July 2003

Mechanism-based proteomic screening identifies targets of thioredoxin-like proteins

scientific article

Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis

scientific article

Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival

scientific article

Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis

scientific journal article

Methylation by Set9 modulates FoxO3 stability and transcriptional activity.

scientific article

Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation.

scientific article published on July 2016

Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

scientific article published in May 2002

Modulation of an RNA-binding protein by abscisic-acid-activated protein kinase.

scientific article published on August 2002

Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome.

scientific article

Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins

scientific article

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

scientific article published on 31 May 2017

Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling

scientific article published in April 2017

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

scientific article

Multiplexed Isobaric Tag-Based Profiling of Seven Murine Tissues Following In Vivo Nicotine Treatment Using a Minimalistic Proteomics Strategy.

scientific article

Multiplexed Phosphoproteomic Profiling Using Titanium Dioxide and Immunoaffinity Enrichments Reveals Complementary Phosphorylation Events

scientific article

Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multienzyme catalysis

scientific article

Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains.

scientific article published on 27 October 2015

Mycobacterium tuberculosis prokaryotic ubiquitin-like protein-deconjugating enzyme is an unusual aspartate amidase

scientific article

Network organization of the human autophagy system

scientific article

Network-based inference from complex proteomic mixtures using SNIPE.

scientific article

Neutral Loss Is a Very Common Occurrence in Phosphotyrosine-Containing Peptides Labeled with Isobaric Tags

scientific article

Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability.

scientific article

Nicotine-induced protein expression profiling reveals mutually altered proteins across four human cell lines

scientific article

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

scientific article published in January 2018

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

scientific article (publication date: 3 March 2005)

OR08-3 The Role Of Neuronal Plasticity In The Timing Of Puberty Onset: Insights From A Mkrn3 Deficient Mouse Model.

scientific article

Optimization and use of peptide mass measurement accuracy in shotgun proteomics

scientific article published on 23 April 2006

Optimized Workflow for Multiplexed Phosphorylation Analysis of TMT-Labeled Peptides Using High-Field Asymmetric Waveform Ion Mobility Spectrometry

scientific article published on 18 December 2019

Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL

scientific article

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.

scientific article published on September 2016

PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes.

scientific article

PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity.

scientific article

PP2ARts1 is a master regulator of pathways that control cell size

scientific article published on February 2014

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

scientific article published on 20 June 2016

Parallel Notched Gas-Phase Enrichment for Improved Proteome Identification and Quantification with Fast Spectral Acquisition Rates

scientific article published on 17 February 2020

Phosphoproteome Analysis of Fission Yeast

article

Phosphoproteome analysis of Drosophila melanogaster embryos

scientific article published on 8 March 2008

Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

scientific article

Phosphoproteomic analysis of the developing mouse brain

scientific article

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase

scientific article

Phosphorylation controls autoinhibition of cytoplasmic linker protein-170

scientific article

Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration

scientific article published in November 2005

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes

scientific article published on 29 March 2018

Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage.

scientific article

Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun N-terminal kinase promotes stress-dependent P-body assembly.

scientific article

Photochromic agents as tools for protein structure study: lapachenole is a photoaffinity ligand of cytochrome P450 3A4.

scientific article

Photoreactive stapled BH3 peptides to dissect the BCL-2 family interactome.

scientific article

Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony

scientific article (publication date: 17 February 2017)

Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.

scientific article

Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks

scientific article published on 13 June 2016

Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells

scientific article (publication date: 26 October 2010)

Profiling of UV-induced ATM/ATR signaling pathways.

scholarly article

Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected]

scientific journal article

Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells

scientific article

Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase

scientific article

Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain

scientific journal article

Proteasomal control of cytokinin synthesis protects Mycobacterium tuberculosis against nitric oxide

scientific journal article

Protein profiling with cleavable isotope-coded affinity tag (cICAT) reagents: the yeast salinity stress response

scientific article published on 23 September 2003

Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags

scientific article

Proteome-Wide Protein Expression Profiling Across Five Pancreatic Cell Lines

scientific article

Proteome-wide quantitative multiplexed profiling of protein expression: carbon-source dependency in Saccharomyces cerevisiae

scientific article

Proteome-wide systems analysis of a cellulosic biofuel-producing microbe

scientific article

Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response.

scientific article

Proteomic Profiling of ClpXP Substrates after DNA Damage Reveals Extensive Instability within SOS Regulon

article

Proteomic Profiling of Paclitaxel Treated Cells Identifies a Novel Mechanism of Drug Resistance Mediated by PDCD4.

scientific article

Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling

scientific article

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

scientific article

Proteomic insights into ubiquitin and ubiquitin-like proteins.

scientific article

Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements

scientific article

Proteomics identifies multipotent and low oncogenic risk stem cells of the spleen

scientific article

Proteomics of Primary Cilia by Proximity Labeling

scientific article published on 11 November 2015

Proteomics of phosphorylation and protein dynamics during fertilization and meiotic exit in the Xenopus egg.

scientific article published on 28 November 2017

Purification and architecture of the ubiquitous Wave complex

scholarly article

Purification of active TFIID from Saccharomyces cerevisiae. Extensive promoter contacts and co-activator function

scientific article

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

scientific article

Quantitative Proteome Responses to Oncolytic Reovirus in GM-CSF- and M-CSF-Differentiated Bone Marrow-Derived Cells

scientific article published on 17 January 2020

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

scientific article published on 3 June 2015

Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages

scientific article

Quantitative analysis of Y-Chromosome gene expression across 36 human tissues

scientific article published on 27 May 2020

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

article

Quantitative cancer proteomics: stable isotope labeling with amino acids in cell culture (SILAC) as a tool for prostate cancer research

scientific article

Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation ⬇️

scientific article published on April 6, 2013

Quantitative mass spectrometry-based multiplexing compares the abundance of 5000 S. cerevisiae proteins across 10 carbon sources

scientific article published on 15 July 2016

Quantitative multiplexed proteomics of Taenia solium cysts obtained from the skeletal muscle and central nervous system of pigs

scientific article published on 25 September 2017

Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells

scientific article

Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors.

scientific article

Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.

scientific article

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

scientific article

Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.

scientific article

Quantitative temporal viromics: an approach to investigate host-pathogen interaction

scientific article

REMOVED: Identification of a unique molecular and functional microglia signature in health and disease

article

RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks

scientific article

RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing

scientific article published on 01 May 2007

RNAi-mediated targeting of heterochromatin by the RITS complex

scientific article

Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport

scientific article

Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coli

scientific article

Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex

scientific article

Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins ⬇️

scientific article published on October 17, 2011

Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine

scientific article published on 9 October 2015

Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation

scientific article published on November 2009

Regulation of microtubule-based transport by MAP4

scientific article

Regulation of monoubiquitinated PCNA by DUB autocleavage

scientific journal article

Regulation of neuronal cell death by MST1-FOXO1 signaling

scientific article

Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries

scientific article published on 04 January 2021

Reply to "Phosphorylation sites of higher stoichiometry are more conserved"

Ribosome binding of a single copy of the SecY complex: implications for protein translocation

scientific article

Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction ⬇️

scientific article published on September 10, 2010

Rixosomal RNA degradation contributes to silencing of Polycomb target genes

scientific article published on 30 March 2022

Role for perinuclear chromosome tethering in maintenance of genome stability.

scientific article

Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes

scientific journal article

Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity

scientific article

S. pombe LSD1 Homologs Regulate Heterochromatin Propagation and Euchromatic Gene Transcription

article

S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains

scientific article published on 23 April 2009

SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway.

scientific article

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

scientific article

SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.

scientific article

SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma

scientific article

SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration

scientific article

SILVER helps assign peptides to tandem mass spectra using intensity-based scoring.

scientific article

SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase.

scientific article published in June 2012

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase

scientific journal article

SKAR is a specific target of S6 kinase 1 in cell growth control

scientific article

SR proteins function in coupling RNAP II transcription to pre-mRNA splicing.

scientific article

SUMO regulates the assembly and function of a cytoplasmic intermediate filament protein in C. elegans

scientific article

SUMOylation of Psmd1 controls Adrm1 interaction with the proteasome

scientific article

SUMOylation of pancreatic glucokinase regulates its cellular stability and activity

scientific article published on 7 January 2013

Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome

scientific article (publication date: 21 June 2011)

Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts

scientific article published on 15 August 2013

Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay

scientific article published on 13 April 2020

Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis

scientific article published on 20 October 2011

Selenoprotein S is involved in maintenance and transport of multiprotein complexes

scientific article published on September 2014

Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry

scientific article (publication date: 14 May 2004)

Sensitive multiplexed analysis of kinase activities and activity-based kinase identification

scientific article

Serpin 2a is induced in activated macrophages and conjugates to a ubiquitin homolog

scientific article published on March 2002

Signaling networks assembled by oncogenic EGFR and c-Met

scholarly article

Single Copies of Sec61 and TRAP Associate with a Nontranslating Mammalian Ribosome

scientific article

Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae

scientific article published on 15 September 2008

Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation

scientific article published on June 2002

Strain-Specific Peptide (SSP) Interference Reference Sample: A Genetically Encoded Quality Control for Isobaric Tagging Strategies

scientific article published on 18 March 2021

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

scientific article

Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).

scientific article published on 13 February 2017

Structural Defects in the Regulatory Particle-Core Particle Interface of the Proteasome Induce a Novel Proteasome Stress Response ⬇️

scientific article published on August 30, 2011

Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity

scientific article

Super Heavy TMTpro Labeling Reagent: An Alternative and Higher-Charge-State-Amenable Stable-Isotope-Labeled TMTpro Variant

scientific article published in 2021

Survey of activated FLT3 signaling in leukemia

scientific article

Systematic and quantitative assessment of the ubiquitin-modified proteome

scientific article

TAK1 is an essential regulator of BMP signalling in cartilage

scientific journal article

TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex

scientific article

TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples

scientific article published on 16 March 2020

Target-decoy search strategy for mass spectrometry-based proteomics

scientific article

Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

scientific article

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.

scientific article

Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation

scientific article

Temporal Proteomic Profiling of SH-SY5Y Differentiation with Retinoic Acid Using FAIMS and Real-Time Searching

scientific article published on 15 October 2020

Tetracyclines promote survival and fitness in mitochondrial disease models

scientific article published in 2021

The Absolute Quantification Strategy: Application to Phosphorylation Profiling of Human Separase Serine 1126

The BioPlex Network: A Systematic Exploration of the Human Interactome

scientific article

The C-terminal tail of tetraspanin protein CD9 contributes to its function and molecular organization ⬇️

scientific article published on July 19, 2011

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

scientific journal article

The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle

scientific article

The Hippo signaling pathway interactome

scientific article

The Membrane Stress Response Buffers Lethal Effects of Lipid Disequilibrium by Reprogramming the Protein Homeostasis Network ⬇️

scientific article published on September 20, 2012

The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator

scientific article published on 28 March 2016

The Nuclear Proteome of a Vertebrate

scientific article

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

scientific article

The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8.

scientific article published on November 2008

The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry

scientific article published on January 2008

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

scientific journal article

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1

scientific journal article

The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications

scientific article

The absolute quantification strategy: application to phosphorylation profiling of human separase serine 1126.

scientific article

The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

scientific article

The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia

scientific article

The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis

scientific article

The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.

scientific article published on 8 November 2012

The effects of mass accuracy, data acquisition speed, and search algorithm choice on peptide identification rates in phosphoproteomics

scientific article

The effects of nonignorable missing data on label-free mass spectrometry proteomics experiments

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

scientific article published on 20 August 2007

The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8

scientific article

The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation

scientific article

The histone demethylase LSD1/KDM1A promotes the DNA damage response

scientific article

The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking

scientific article published on 4 March 2008

The impact of microRNAs on protein output

scientific article

The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses

scientific article published on 18 September 2008

The influence of signals from chilled roots on the proteome of shoot tissues in rice seedlings

scientific article published on 6 June 2013

The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

scientific article

The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides

scientific article

The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival

scientific article published on 7 June 2017

The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2

scientific article

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

scientific article

The septins function in G1 pathways that influence the pattern of cell growth in budding yeast.

scientific article

The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects

scientific article published on 27 November 2017

The tumor suppressor CYLD regulates entry into mitosis

scientific article

The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling

scientific article published on October 2005

The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition

scientific article

The ubiquitin-proteasome system regulates membrane fusion of yeast vacuoles

scientific article

Thiol-based direct threat sensing by the stress-activated protein kinase Hog1

scientific article published on 26 November 2019

Thrap3 docks on phosphoserine 273 of PPARγ and controls diabetic gene programming

scientific article

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex

scientific article

Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC.

scientific article

Transcription factor networks in Drosophila melanogaster

scientific article

Transcriptional and proteomic profiles of group B Streptococcus type V reveal potential adherence proteins associated with high-level invasion

scientific article published on 8 January 2007

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.

scientific article published on January 2010

Trim32 reduces PI3K-Akt-FoxO signaling in muscle atrophy by promoting plakoglobin-PI3K dissociation

scientific article published on 24 February 2014

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

scientific article

Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

scientific article

Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast

UAF1 is a subunit of multiple deubiquitinating enzyme complexes

scientific article

UBE2O remodels the proteome during terminal erythroid differentiation.

scientific article

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction

scientific article

UHRF1 is a sensor for DNA interstrand crosslinks and recruits FANCD2 to initiate the Fanconi anemia pathway.

scientific article

USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites

scientific article published on 13 April 2016

Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities.

scientific article

Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis

scientific article

Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

scientific article

Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription

scientific article published on 22 June 2017

Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation

scientific article

WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex

scientific journal article

Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics

scientific article

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? ⬇️

scientific article published on January 11, 2013

Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.

scientific article published in April 2012

eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference.

scientific article published on 28 May 2015

iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis

scientific article

mTMT: An Alternative, Nonisobaric, Tandem Mass Tag Allowing for Precursor-Based Quantification

scientific article published on 20 September 2019

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

scientific article

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy

scientific article

p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling

scientific article published on 30 March 2009

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